João Rodrigues may refer to:
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João Rodrigues Tçuzu (1561–1633), Portuguese Jesuit missionary in Japan and China
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Juan Rodriguez (trader) (1500s–1600s), also known as Juan Rodriguez or Jan Rodrigues, first known non-indigenous resident of Manhattan
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João Barbosa Rodrigues (1842–1909), Brazilian botanist
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João Pedro Rodrigues (born 1966), Portuguese film director
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João Rodrigues (sailor) (born 1971), Portuguese Olympic sailor
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João Rodrigues (cyclist) (born 1994), Portuguese road racing cyclist
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Joao Rodríguez (footballer) (born 1996), Colombian footballer who plays for Central Córdoba
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João Rodrigues (musician), Portuguese drummer and member of the band
Napa
{{hndis, Rodrigues, João