Jesuit's Bark
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Jesuit's bark, also known as cinchona bark, Peruvian bark or China bark, is a former remedy for
malaria Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomitin ...
, as the bark contains
quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg ...
, used to treat the disease. The
bark Bark may refer to: Common meanings * Bark (botany), an outer layer of a woody plant such as a tree or stick * Bark (sound), a vocalization of some animals (which is commonly the dog) Arts and entertainment * ''Bark'' (Jefferson Airplane album), ...
of several species of the genus ''
Cinchona ''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the Tropical Andes, tropical Andean forests of western South America. A few species are ...
'', family
Rubiaceae Rubiaceae () is a family (biology), family of flowering plants, commonly known as the coffee, madder, or bedstraw family. It consists of terrestrial trees, shrubs, lianas, or herbs that are recognizable by simple, opposite leaves with Petiole ( ...
indigenous to the western
Andes The Andes ( ), Andes Mountains or Andean Mountain Range (; ) are the List of longest mountain chains on Earth, longest continental mountain range in the world, forming a continuous highland along the western edge of South America. The range ...
of South America, was introduced to
Jesuit The Society of Jesus (; abbreviation: S.J. or SJ), also known as the Jesuit Order or the Jesuits ( ; ), is a religious order (Catholic), religious order of clerics regular of pontifical right for men in the Catholic Church headquartered in Rom ...
missionaries during the 17th century as a traditional treatment for malaria by indigenous people in Peru.


History

The postcolonial history of cinchona bark dates back more than 350 years. Circa 1650, the physician Sebastiano Bado declared that this bark had proved more precious to mankind than all the gold and silver that the Spaniards had obtained from South America. In the 18th century, the Italian professor of medicine
Bernardino Ramazzini Bernardino Ramazzini (; 4 October 1633 – 5 November 1714) was an Italian physician. Ramazzini, along with Francesco Torti, was an early proponent of the use of cinchona bark (from which quinine is derived) in the treatment of malaria. His most ...
said that the introduction of Peruvian bark would be of the same importance to medicine that the discovery of
gunpowder Gunpowder, also commonly known as black powder to distinguish it from modern smokeless powder, is the earliest known chemical explosive. It consists of a mixture of sulfur, charcoal (which is mostly carbon), and potassium nitrate, potassium ni ...
was to the art of war, an opinion endorsed by contemporary writers on the
history of medicine The history of medicine is both a study of medicine throughout history as well as a multidisciplinary field of study that seeks to explore and understand medical practices, both past and present, throughout human societies. The history of med ...
. The value of Jesuit's bark, and the controversy surrounding it, were both recognized by
Benjamin Franklin Benjamin Franklin (April 17, 1790) was an American polymath: a writer, scientist, inventor, statesman, diplomat, printer, publisher and Political philosophy, political philosopher.#britannica, Encyclopædia Britannica, Wood, 2021 Among the m ...
, who wittily commented upon it in his ''
Poor Richard's Almanack ''Poor Richard's Almanack'' (sometimes ''Almanac'') was a yearly almanac published by Benjamin Franklin, who adopted the pseudonym of "Poor Richard" or "Richard Saunders" for this purpose. The publication appeared continually from 1732 to 1758. ...
'' for October 1749, telling the story of Robert Talbot's use of it to cure the French Dauphin. Hugh Algernon Weddell observed, "Few subjects in natural history have excited general interest in a higher degree than cinchona; none perhaps have hitherto merited the attention of a greater number of distinguished men". Dissension, however, was rife at the time, mainly due to its source of discovery, the Jesuits.
Alexander von Humboldt Friedrich Wilhelm Heinrich Alexander von Humboldt (14 September 1769 – 6 May 1859) was a German polymath, geographer, natural history, naturalist, List of explorers, explorer, and proponent of Romanticism, Romantic philosophy and Romanticism ...
said, "It almost goes without saying that among Protestant physicians hatred of the Jesuits and religious intolerance lie at the bottom of the long conflict over the good or harm effected by Peruvian Bark". The Spanish Jesuit missionaries in Peru were taught the healing power of the bark by natives, between 1620 and 1630, when a Jesuit at Loxa was indebted to its use for his cure from an attack of malaria (''Loxa Bark''). It was used at the recommendation of the Jesuits in 1630, when the Countess of Chinchon (Cinchon; the derivative is Cinchona, the appellation selected by
Carl Linnaeus Carl Linnaeus (23 May 1707 – 10 January 1778), also known after ennoblement in 1761 as Carl von Linné,#Blunt, Blunt (2004), p. 171. was a Swedish biologist and physician who formalised binomial nomenclature, the modern system of naming o ...
in 1742;
Clements Markham Sir Clements Robert Markham (20 July 1830 – 30 January 1916) was an English geographer, explorer and writer. He was secretary of the Royal Geographical Society (RGS) between 1863 and 1888, and later served as the Society's president fo ...
preferred "Chinchona",Conrad Wesselhoeft (July 1916) "The discovery of the cinchona bark," ''The New England Medical Gazette'', 51 : 349–361; see especiall
pp. 357–358.
/ref> ), wife of the new
viceroy A viceroy () is an official who reigns over a polity in the name of and as the representative of the monarch of the territory. The term derives from the Latin prefix ''vice-'', meaning "in the place of" and the Anglo-Norman ''roy'' (Old Frenc ...
, who had just arrived from Europe, was taken ill with malaria at
Lima Lima ( ; ), founded in 1535 as the Ciudad de los Reyes (, Spanish for "City of Biblical Magi, Kings"), is the capital and largest city of Peru. It is located in the valleys of the Chillón River, Chillón, Rímac River, Rímac and Lurín Rive ...
. The countess was saved from death, and in thanksgiving caused large quantities of the bark to be collected. This she distributed to malaria sufferers, partly in person and partly through the Jesuits of St. Paul's College at Lima (''pulvis comitissæ''). She returned to Europe in 1640 and was the first to bring the bark there to spread its use through Spain and the rest of the continent, as stated by Markham. The Jesuit Barnabé de Cobo, in his capacity as procurator of the Peruvian province of his order, is credited with first bringing the bark from Lima to Spain, and afterwards to
Rome Rome (Italian language, Italian and , ) is the capital city and most populated (municipality) of Italy. It is also the administrative centre of the Lazio Regions of Italy, region and of the Metropolitan City of Rome. A special named with 2, ...
and other parts of Italy, in 1632. In the meanwhile its merits must have been ascertained both in Lima and in various parts of Europe, as Count Chinchon and his physician Juan de Vega brought it back with them in 1640. Count Chinchon, however, troubled himself little about the use or sale of the bark. A greater distribution resulted from the large quantity brought over by the Jesuit
Bartolomé Tafur Bartolomé may refer to: People * Bartolomé Abdala (born 1964), Argentine politician * Bartolomé Bermejo (c.1440–c.1501), Spanish painter * Bartolomé de las Casas (1484–1566), Spanish priest * Bartolomé Castagnola (born 1970), Argentine pol ...
, who, like Cobo, came to Spain in 1643 while procurator of the Peruvian province of his order, proceeded through France (there is an alleged cure of the young
Louis XIV LouisXIV (Louis-Dieudonné; 5 September 16381 September 1715), also known as Louis the Great () or the Sun King (), was King of France from 1643 until his death in 1715. His verified reign of 72 years and 110 days is the List of longest-reign ...
, when still dauphin, effected by Father Tafur by means of Peruvian bark), and thence to Italy as far as Rome. Jesuit theologian John de Lugo learned about the cinchona from Tafur in 1643, and became an outspoken advocate for it throughout Europe, earning him the nickname . The pope's physician, Gabriel da Fonseca, analyzed the bark at de Lugo's request, reported on it favorably, and supported its distribution among the sick in Rome. Among those who came to support the drug through de Lugo's influence was Pietro Paolo Pucciarini, a lay brother and
apothecary ''Apothecary'' () is an Early Modern English, archaic English term for a medicine, medical professional who formulates and dispenses ''materia medica'' (medicine) to physicians, surgeons and patients. The modern terms ''pharmacist'' and, in Brit ...
in the Jesuit College at Rome. Pucciarini was instrumental in the drug's distribution, and published the '' Schedula Romana'' giving directions for its use as early as 1651. In his friend Honoré Fabri, a French Jesuit, who stayed for a time in Rome, de Lugo won a determined defender of the bark against the first anticinchona pamphlet written by the Brussels doctor
Jean-Jacques Chifflet Jean-Jacques Chifflet (Chiflet) (Besançon, 1588–1660) was a physician, jurist, antiquarian and archaeologist originally from the County of Burgundy (now in France). Life He visited Paris and Montpellier, and travelled in Italy and Germany. ...
. Under the pseudonym of Antimus Conygius, Fabri wrote in 1655 the first paper on cinchona published in Italy, as well as the first of the long list of brochures defending its use and the only independent article on this bark which has been issued by a Jesuit. The two Genoese, Girolamo Bardi, a priest, and Sebastiano Baldo, a physician, who were among the pioneer advocates of the plant, were intimate with the cardinal, and Baldo prefixed to his principal work a letter from de Lugo, dated 1659, on cinchona, which shows that the cardinal even when seventy-seven years old was still active in its behalf. Circumstances created a suitable opportunity for disseminating the bark from Rome throughout Europe by means of the Jesuits. In 1646, 1650, and 1652 the delegates to the eighth, ninth, and tenth general councils of the order (three from each province) returned to their homes, taking it with them, and at the same time there is evidence of its use in the Jesuit colleges at
Genoa Genoa ( ; ; ) is a city in and the capital of the Italian region of Liguria, and the sixth-largest city in Italy. As of 2025, 563,947 people live within the city's administrative limits. While its metropolitan city has 818,651 inhabitan ...
,
Lyon Lyon (Franco-Provençal: ''Liyon'') is a city in France. It is located at the confluence of the rivers Rhône and Saône, to the northwest of the French Alps, southeast of Paris, north of Marseille, southwest of Geneva, Switzerland, north ...
,
Leuven Leuven (, , ), also called Louvain (, , ), is the capital and largest City status in Belgium, city of the Provinces of Belgium, province of Flemish Brabant in the Flemish Region of Belgium. It is located about east of Brussels. The municipalit ...
, Ratisbon, etc. The remedy – connected with the name of Jesuit – very soon reached England. The English weekly '' Mercurius Politicus'' in 1658 contained in four numbers the announcement that: "The excellent powder known by the name of 'Jesuit's powder' may be obtained from several London chemists". It remains to recall the fact that even in the 17th and 18th centuries the bark kept in the Jesuit pharmacies or in their colleges was considered particularly efficacious because they were better able to provide a genuine unadulterated supply. Further, that in those two centuries Jesuit missionaries took the remedy to the malaria regions of foreign countries, even reaching the courts of
Peking Beijing, previously romanized as Peking, is the capital city of China. With more than 22 million residents, it is the world's most populous national capital city as well as China's second largest city by urban area after Shanghai. It is l ...
, China and
Kyoto Kyoto ( or ; Japanese language, Japanese: , ''Kyōto'' ), officially , is the capital city of Kyoto Prefecture in the Kansai region of Japan's largest and most populous island of Honshu. , the city had a population of 1.46 million, making it t ...
, Japan, where they cured the emperor by its means; that in Peru during the 18th century they urged American collectors to lay out new plantations; and in the 19th century they were the first to plant cinchona outside of South America.


See also

*
History of malaria The history of malaria extends from its prehistoric origin as a zoonotic disease in the primates of Africa through to the 21st century. A widespread and potentially lethal human infectious disease, at its peak malaria infested every continent e ...
*
Luis Jerónimo de Cabrera, 4th Count of Chinchón Luis Jerónimo Fernández de Cabrera Bobadilla Cerda y Mendoza, 4th Count of Chinchón, also known as Luis Xerónimo Fernandes de Cabrera Bobadilla y Mendoza, (1589 in Madrid – October 28, 1647 in Madrid) was a Spanish nobleman, Comendador ...
* Schedula Romana * Therapeutice Specialis * Juan de Lugo


References


Further reading

* * *


External links

* {{catholic, wstitle=Jesuit's bark Medicinal plants Quinine Antimalarial agents Natural history of Peru