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A chemical peel is a treatment used to improve and smooth the texture of the
skin Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different ...
. The skin on the face is most commonly treated, but peels can also be performed on the body. Chemical peels are intended to remove the outermost layers of the skin. To accomplish this task, the chosen peel solution induces a controlled injury to the skin, which causes the skin to peel. This process leads to smoother skin can improve fine lines, acne scars, and pigment. Medium depth peels must be performed by a medical provider (MD, NP, RN, or AP Esthetician in certain states). There are several types of chemical peels.Chemical Peels , The Ageing Skin
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''α''-hydroxy acid peels

Alpha hydroxy acid Alpha hydroxy carboxylic acids, or α-hydroxy carboxylic acids (AHAs), are a group of carboxylic acids featuring a hydroxy group located ''one'' carbon atom away from the acid group. This structural aspect distinguishes them from beta hydroxy aci ...
s (AHAs) are naturally occurring
carboxylic acid In organic chemistry, a carboxylic acid is an organic acid that contains a carboxyl group () attached to an Substituent, R-group. The general formula of a carboxylic acid is often written as or , sometimes as with R referring to an organyl ...
s such as
glycolic acid Glycolic acid (or hydroxyacetic acid; chemical formula ) is a colorless, odorless and hygroscopic crystal, crystalline solid, highly solubility, soluble in water. It is used in various skin care, skin-care products. Glycolic acid is widespread in ...
, a natural constituent of sugar cane juice, and
lactic acid Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as wel ...
, found in sour milk and tomato juice as well as being produced endogenously during normal
metabolism Metabolism (, from ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cellular processes; the co ...
and
exercise Exercise or workout is physical activity that enhances or maintains fitness and overall health. It is performed for various reasons, including weight loss or maintenance, to aid growth and improve strength, develop muscles and the cardio ...
. This is the mildest of the peel formulas and produces light peels for treatment of fine wrinkles, areas of dryness, uneven pigmentation and acne. Alpha hydroxy acids can also be mixed with facial washes, serums or creams in lesser concentrations as part of a daily skin-care regimen to improve the skin's texture. There are five usual fruit acids:
citric acid Citric acid is an organic compound with the formula . It is a Transparency and translucency, colorless Weak acid, weak organic acid. It occurs naturally in Citrus, citrus fruits. In biochemistry, it is an intermediate in the citric acid cycle, ...
,
glycolic acid Glycolic acid (or hydroxyacetic acid; chemical formula ) is a colorless, odorless and hygroscopic crystal, crystalline solid, highly solubility, soluble in water. It is used in various skin care, skin-care products. Glycolic acid is widespread in ...
,
lactic acid Lactic acid is an organic acid. It has the molecular formula C3H6O3. It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as wel ...
,
malic acid Malic acid is an organic compound with the molecular formula . It is a dicarboxylic acid that is made by all living organisms, contributes to the sour taste of fruits, and is used as a food additive. Malic acid has two stereoisomeric forms ( ...
and
tartaric acid Tartaric acid is a white, crystalline organic acid that occurs naturally in many fruits, most notably in grapes but also in tamarinds, bananas, avocados, and citrus. Its salt (chemistry), salt, potassium bitartrate, commonly known as cream of ta ...
. Many other alpha hydroxy acids exist and are used. AHA peels are not indicated for treating wrinkles. AHA peels may cause stinging, skin redness, mild skin irritation, and dryness. Higher pH levels and lower percentages of hydroxy acids are commonly used as home peels. These will not work as quickly as an in-office procedure, but can be economical for many people.


β hydroxy acid peels

Salicylic acid Salicylic acid is an organic compound with the formula HOC6H4COOH. A colorless (or white), bitter-tasting solid, it is a precursor to and a active metabolite, metabolite of acetylsalicylic acid (aspirin). It is a plant hormone, and has been lis ...
is a beta hydroxy acid. It is antibacterial (mostly bacteriostatic, except in high concentrations when it is more frequently bactericidal) and anti-inflammatory which helps treat acne.. Salicylic acid also has the ability to reduce the spots and bumps associated with acne. It is becoming common for
beta hydroxy acid A beta hydroxy carboxylic acid or β-hydroxy carboxylic acid (BHA) is a carboxylic acid containing a hydroxy functional group separated by ''two'' carbon atoms. They are related to alpha hydroxy acids, in which the two functional groups are sep ...
(BHA) peels to be used instead of the stronger alpha hydroxy acid (AHA) peels due to BHA's being oil soluble. Studies show that BHA peels control sebum excretion, acne as well as remove dead skin cells to a certain extent better than AHAs due to AHAs only working on the surface of the skin.


Retinoic acid peel

Retinoic acid Retinoic acid (simplified nomenclature for all-''trans''-retinoic acid) is a metabolite of vitamin A1 (all-''trans''-retinol) that is required for embryonic development, male fertility, regulation of bone growth and immune function. All-''trans ...
is a
retinoid The retinoids are a class of chemical compounds that are natural derivatives of vitamin A or are chemically related to it. Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms of cancer ...
. This type of facial peel is also performed in the office of a plastic surgeon, oral and maxillofacial surgeon, or a provider in a medical spa setting. This is a deeper peel than the beta hydroxy acid peel and is used to treat scars, wrinkles, and pigment. It is usually performed in conjunction with a Jessner; which is performed right before, in order to open up the skin, so the retinoic acid can penetrate deeper into the skin. The client leaves with the chemical peel solution on their face. The peeling process takes place on the third day. More dramatic changes to the skin require multiple peels over time.


Phenol-croton oil peel

A
phenol Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile and can catch fire. The molecule consists of a phenyl group () ...
-
croton oil Croton oil (''Crotonis oleum'') is an oil prepared from the seeds of '' Croton tiglium'', a tree belonging to the order Euphorbiales and family Euphorbiaceae, and native or cultivated in India and the Malay Archipelago. Small doses taken interna ...
is a type of chemical peel. The term "phenol-croton oil peel" has replaced the vague term "phenol peel" in medical literature. It was originally used on a clandestine basis by early Hollywood stars in the 1920s and was incorporated into mainstream practice in the 1960s by Thomas Baker and Howard Gordon. The active ingredient is
croton oil Croton oil (''Crotonis oleum'') is an oil prepared from the seeds of '' Croton tiglium'', a tree belonging to the order Euphorbiales and family Euphorbiaceae, and native or cultivated in India and the Malay Archipelago. Small doses taken interna ...
, which causes an intense caustic exfoliating reaction in the skin.


History

Resurfacing and restoring skin with chemical peel was introduced in the second half of the 19th century by the Austrian dermatologist
Ferdinand Ritter von Hebra Ferdinand Karl Franz Schwarzmann, Ritter von Hebra (7 September 1816 – 5 August 1880) was an Austrian physician and dermatologist known as the founder of the New Vienna School of Dermatology, an important group of physicians who established ...
(1816–1880), founder of the Vienna School of Dermatology. He used exfoliative agents, like phenol, croton oil, nitric acid in various caustic combinations for treating freckles and skin irregularities.


Complications

The deeper the peel, the more complications that can arise. Professional strength chemical peels are typically administered by certified dermatologists or licensed estheticians. Professional peels and lower-concentration DIY home peel kits can pose health risks, including injury and scarring of the skin. Possible complications include photosensitivity, prolonged
erythema Erythema (, ) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology inc ...
, pigmentary changes,
milia A milium (: milia), also called a milk spot or an oil seed, is a clog of the eccrine sweat gland. It is a keratin-filled cyst that may appear just under the epidermis or on the roof of the mouth.Freedberg, et al. (2003). ''Fitzpatrick's Dermatolo ...
, skin atrophy, and textural changes. Many individuals report professional chemical peels leave a minor yellowish tinge on their skin due to the retinol elements in the peel. This is expected to last 2–3 hours maximum. Varying mild to moderate redness after the procedure is expected.


Anesthesia

Light chemical peels like AHA and BHA are usually done in medical offices or Med Spas. There is minimal
discomfort Comfort is a state of physical or psychological ease, often characterized by the absence of hardship. Individuals experiencing a lack of comfort are typically described as uncomfortable or in discomfort. A degree of psychological comfort can b ...
so usually no
anesthetic An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia ⁠— ⁠in other words, to result in a temporary loss of sensation or awareness. They may be divided into t ...
is given because the patient feels only a slight stinging when the
solution Solution may refer to: * Solution (chemistry), a mixture where one substance is dissolved in another * Solution (equation), in mathematics ** Numerical solution, in numerical analysis, approximate solutions within specified error bounds * Solu ...
is applied. Medium peels such as
trichloroacetic acid Trichloroacetic acid (TCA; TCAA; also known as trichloroethanoic acid) is an analogue of acetic acid in which the three hydrogen atoms of the methyl group have all been replaced by chlorine atoms. Salts and esters of trichloroacetic acid are cal ...
(TCA) are also performed in the doctor's office or in an
ambulatory surgery center Outpatient surgery, also known as ambulatory surgery, day surgery, day case surgery, or same-day surgery, is surgery that does not require an overnight hospital stay.The International Association for Ambulatory Surgery (IAAS) would not consider al ...
as an outpatient procedure and can cause more discomfort. Frequently, the combination of a
tranquilizer A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are central nervous system (CNS) depressants and interact with brain activity, causing its deceleration. Various kinds of sedatives c ...
such as
diazepam Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is used to treat a range of conditions, including anxiety disorder, anxiety, seizures, alcohol withdrawal syndr ...
and an oral analgesic is administered. TCA peels often do not require anesthesia even if the solution itself has - at the contrary of phenol - no numbing effect on the skin. The
patient A patient is any recipient of health care services that are performed by Health professional, healthcare professionals. The patient is most often Disease, ill or Major trauma, injured and in need of therapy, treatment by a physician, nurse, op ...
usually feels a warm or burning sensation.Halaas YP: Medium depth peels. Facial Plas Surg Clin North Am 2004 Aug; 12(3):297-303
Phenol Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula . It is a white crystalline solid that is volatile and can catch fire. The molecule consists of a phenyl group () ...
used to be a deep chemical peel. Early phenol peel solutions were very painful and most practitioners would perform it under either
general anesthesia General anaesthesia (UK) or general anesthesia (US) is medically induced loss of consciousness that renders a patient unarousable even by painful stimuli. It is achieved through medications, which can be injected or inhaled, often with an analgesi ...
, administered by an anesthesiologist or nurse anesthetist. Today it is more correctly referred to as a
croton oil Croton oil (''Crotonis oleum'') is an oil prepared from the seeds of '' Croton tiglium'', a tree belonging to the order Euphorbiales and family Euphorbiaceae, and native or cultivated in India and the Malay Archipelago. Small doses taken interna ...
peel, since that has proven to be the active ingredient responsible for most of its effects. Recent formulations allow more variation in the depth of treatment, and allow its use under
sedation Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure. Examples of drugs which can be used for sedation include isoflurane, diethyl ether, ...
either orally or intravenously, usually in conjunction with local anesthetic injections.


See also

*
List of cutaneous conditions Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the Human body, body and composed of Human skin, skin, hair, Nail (anatomy), nails, and related muscle and glands. The major function o ...


References

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External links


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