James Wayne may refer to:
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James M. Wayne (1790–1867), U.S. Supreme Court justice and U.S. representative
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SS James M. Wayne, a Liberty ship
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James Wayne (R&B musician) (1920–1978), American rhythm and blues musician who also recorded as James Waynes and "Wild Willie" Wayne
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Jimmy Wayne
Jimmy Wayne Barber (born October 23, 1972) is an American country music singer and songwriter. He released his self-titled Jimmy Wayne (album), debut album in 2003 on the DreamWorks Records label. Four singles were released from it, including " ...
(born 1972), American country musician
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''Jimmy Wayne'' (album)
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Jim Wayne, member of the Kentucky House of Representatives
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