Ivan Wallin
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Ivan Emanuel Wallin (22 January 1883 – 6 March 1969) was an American biologist who made the first experimental works on
endosymbiotic theory Symbiogenesis (endosymbiotic theory, or serial endosymbiotic theory,) is the leading evolutionary theory of the origin of eukaryotic cells from prokaryotic organisms. The theory holds that mitochondria, plastids such as chloroplasts, and possibl ...
. Nicknamed the "Mitochondria Man", he claimed that
mitochondria A mitochondrion (; ) is an organelle found in the Cell (biology), cells of most Eukaryotes, such as animals, plants and Fungus, fungi. Mitochondria have a double lipid bilayer, membrane structure and use aerobic respiration to generate adenosi ...
, which are cell organelles, were once independent
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
, as supported by his comparative studies and culture of isolated mitochondria. From 1922, he published a series of papers titled "On the nature of mitochondria" in the '' American Journal of Anatomy'' which became the experimental foundations of his claims. He was the first person to specifically postulate that eukaryotic organelles originated from bacteria, and that
symbiosis Symbiosis (from Greek , , "living together", from , , "together", and , bíōsis, "living") is any type of a close and long-term biological interaction between two different biological organisms, be it mutualistic, commensalistic, or parasit ...
is a major force in creation of new species. Wallin was Professor of Anatomy at the
University of Colorado Medical School The University of Colorado School of Medicine is the medical school of the University of Colorado system. It is located at the Anschutz Medical Campus in Aurora, Colorado, one of the four University of Colorado campuses, six miles east of downtown ...
. He was noted for his eccentric life in academia, such as his preference for exclusively practical demonstration rather than lecturing, his frequent parties for students and an annual Christmas
glögg Glögg, gløgg or glögi ( da, gløgg, no, gløgg, sv, glögg, is, glögg, fo, gløgg, fi, glögi, et, glögi) is a spiced, usually Alcoholic drink, alcoholic, mulled wine or Alcoholic spirit, spirit. It is a traditional Nordic drink dur ...
party.


Biography

Wallin was born to Swedish immigrant parents, Claes Henrik Wallin and Emma Augusta Maria (Johansdotter), in a small farming community at Stanton,
Ohio Ohio () is a state in the Midwestern region of the United States. Of the fifty U.S. states, it is the 34th-largest by area, and with a population of nearly 11.8 million, is the seventh-most populous and tenth-most densely populated. The sta ...
. He was educated at Augustana College at Illinois and
Princeton University Princeton University is a private university, private research university in Princeton, New Jersey. Founded in 1746 in Elizabeth, New Jersey, Elizabeth as the College of New Jersey, Princeton is the List of Colonial Colleges, fourth-oldest ins ...
. He obtained a BS degree from the
University of Iowa The University of Iowa (UI, U of I, UIowa, or simply Iowa) is a public university, public research university in Iowa City, Iowa, United States. Founded in 1847, it is the oldest and largest university in the state. The University of Iowa is org ...
in 1905. He briefly taught biology at the University of Nebraska from where he earned his MSc in 1908. In 1915 he obtained his doctorate degree (DSc) in anatomy from the
New York University New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then-Secretary of the Treasury Albert Gallatin. In 1832, the ...
. His thesis was on the tissue development, differentiation, and morphology of the
lamprey Lampreys (sometimes inaccurately called lamprey eels) are an ancient extant lineage of jawless fish of the order Petromyzontiformes , placed in the superclass Cyclostomata. The adult lamprey may be characterized by a toothed, funnel-like s ...
'' Ammocoete''. From 1918, he was professor of anatomy at the University of Colorado Medical School.


Origin of mitochondria

Wallin was the first to experimentally investigate the origin of mitochondria, particularly in relation to their similarities with certain bacteria. His first paper in 1922 described the staining techniques for bacterial cells, and found that the techniques were equally good for staining mitochondria. He concluded that "bacteria and mitochondria have a similar chemical constitution". His subsequent paper (in the same year and same journal) further strengthened his assumptions. In addition, he observed in his study of
blue green algae Cyanobacteria (), also known as Cyanophyta, are a phylum of gram-negative bacteria that obtain energy via photosynthesis. The name ''cyanobacteria'' refers to their color (), which similarly forms the basis of cyanobacteria's common name, blue ...
that
chloroplasts A chloroplast () is a type of membrane-bound organelle known as a plastid that conducts photosynthesis mostly in plant cell, plant and algae, algal cells. The photosynthetic pigment chlorophyll captures the energy from sunlight, converts it, ...
are "bacteria or bacteria-like organisms that accepted the leisure of a symbiotic partnership in the struggle for existence". He made a summary conclusion that: Wallin was aware that he needed to culture mitochondria isolated from cell in an independent environment. His early experiment was a failure using tissue samples from
guinea pig The guinea pig or domestic guinea pig (''Cavia porcellus''), also known as the cavy or domestic cavy (), is a species of rodent belonging to the genus ''Cavia'' in the family Caviidae. Breeders tend to use the word ''cavy'' to describe the ani ...
, dog, and human
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
. However, he succeeded in obtaining a mitochondrial culture with liver of
fetal A fetus or foetus (; plural fetuses, feti, foetuses, or foeti) is the unborn offspring that develops from an animal embryo. Following embryonic development the fetal stage of development takes place. In human prenatal development, fetal develo ...
and newborn rabbits. He reported his findings in 1924 with a remark that "mitochondria are, in reality, bacterial organisms, symbiotically combined with the tissues of higher organisms." He continued with prolific publications. The series of his papers titled "On the nature of mitochondria" reached nine in 1925. He gave a full description of his experiments and theories on mitochondria in his 1927 book ''Symbionticism and the Origin of Species''. Although he claimed that his experiments were performed with utmost care, critics rejected them on the grounds of possible contamination, and Wallin and his works were largely forgotten, until
Lynn Margulis Lynn Margulis (born Lynn Petra Alexander; March 5, 1938 – November 22, 2011) was an American evolutionary biologist, and was the primary modern proponent for the significance of symbiosis in evolution. Historian Jan Sapp has said that "Lynn Ma ...
introduced a more complete
endosymbiotic theory Symbiogenesis (endosymbiotic theory, or serial endosymbiotic theory,) is the leading evolutionary theory of the origin of eukaryotic cells from prokaryotic organisms. The theory holds that mitochondria, plastids such as chloroplasts, and possibl ...
with better evidences in 1967.


Personal life

Wallin married Eva Louise Shepard. Wallin was known for his eccentric behaviour in his professional life. He avoided lecturing, but instead used practical demonstrations. He frequently organised parties for his students, who in return helped him build a cabin in North St. Vrain Canyon, 20 miles north of
Boulder In geology, a boulder (or rarely bowlder) is a rock fragment with size greater than in diameter. Smaller pieces are called cobbles and pebbles. While a boulder may be small enough to move or roll manually, others are extremely massive. In c ...
. The parties were simply named "Club Wallin" which involved heavy drinking beside playing games. His notable habit was holding an annual Christmas glögg party. At the party guests were treated with Swedish delicacies such as sillsallad (pickled
herring Herring are forage fish, mostly belonging to the family of Clupeidae. Herring often move in large schools around fishing banks and near the coast, found particularly in shallow, temperate waters of the North Pacific and North Atlantic Oceans, i ...
salad),
lutefisk ''Lutefisk'' (Norwegian, in Northern and parts of Central Norway, in Southern Norway; sv, lutfisk ; fi, lipeäkala ; literally "lye fish") is dried whitefish (normally cod, but ling and burbot are also used). It is made from aged stockfi ...
(dried codfish), and
mulled wine Mulled wine, also known as spiced wine, is an alcoholic drink usually made with red wine, along with various mulling spices and sometimes raisins, served hot or warm. It is a traditional drink during winter, especially around Christmas. It is us ...
.


Book

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References


External links


Family history records
{{DEFAULTSORT:Wallin, Ivan 1883 births 1969 deaths American anatomists University of Colorado faculty Augustana College (Illinois) alumni Princeton University alumni University of Iowa alumni New York University alumni People from Stanton, California Symbiogenesis researchers