István Tóth is an

Australian Australian(s) may refer to: Australia * Australia, a country * Australians, citizens of the Commonwealth of Australia ** European Australians ** Anglo-Celtic Australians, Australians descended principally from British colonists ** Aboriginal Aus ...

scientist A scientist is a person who Scientific method, researches to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engag ...

and

chemical engineer A chemical engineer is a professional equipped with the knowledge of chemistry and other basic sciences who works principally in the chemical industry to convert basic raw materials into a variety of Product (chemistry), products and deals with ...

. He is the Chair of Biological Chemistry and Professor of Pharmacy at the

University of Queensland The University of Queensland is a Public university, public research university located primarily in Brisbane, the capital city of the Australian state of Queensland. Founded in 1909 by the Queensland parliament, UQ is one of the six sandstone ...

Education

Has a Master's in Chemical Engineering and a Ph.D. from the Technical University Budapest and is a member of the

Hungarian Academy of Sciences The Hungarian Academy of Sciences ( , MTA) is Hungary’s foremost and most prestigious learned society. Its headquarters are located along the banks of the Danube in Budapest, between Széchenyi rakpart and Akadémia utca. The Academy's primar ...

. Toth is also a fellow of the Queensland Academy of Art and Sciences and

Royal Australian Chemical Institute The Royal Australian Chemical Institute (RACI) is both the qualifying body in Australia for professional chemists and a learned society promoting the science and practice of chemistry in all its branches. The RACI hosts conferences, seminars and ...

, and Affiliated Professorial Research Fellow and Group Leader at Institute of Molecular Biosciences, UQ.

Career

After earning his Ph.D., he spent two years at

Carleton University Carleton University is an English-language public university, public research university in Ottawa, Ontario, Canada. Founded in 1942 as Carleton College, the institution originally operated as a private, non-denominational evening college to se ...

, Ottawa. In 1977, Toth returned to

Budapest Budapest is the Capital city, capital and List of cities and towns of Hungary, most populous city of Hungary. It is the List of cities in the European Union by population within city limits, tenth-largest city in the European Union by popul ...

and began working at the Central Research Institute for Chemistry of the Hungarian Academy of Sciences before relocating to the School of Pharmacy University of London in 1987. In 1994, Toth was awarded a DSc degree by the Hungarian Academy of Sciences for his work on drug delivery. He then joined the University of Queensland in 1998 to lead a productive medicinal chemistry research group and became an Australian citizen in the year 2000. Toth is an elected Fellow of the

, Fellow of the Queensland Academy of Arts and Sciences and Member (External) of the

. In 2009, he received the Adrian Albert award for sustained research in medicinal biochemistry. In 2019, he received the Doctor Honoris Causa Degree by the

Semmelweis University Semmelweis University (Hungarian language, Hungarian: ''Semmelweis Egyetem'', ) is a research-led medical school in Budapest, Hungary, founded in 1769. With six faculties and a doctoral school it covers all aspects of medical and health sciences. ...

Selected publications

* Zhao, L.; Jin, W.; Cruz, J. G.; Marasini, N.; Khalil, Z, G.; Capon, R. J.; Hussein, W. M.; Skwarczynski, M.; Toth, I. Development of polyelectrolyte complexes for the delivery of peptide-based subunit vaccines against group A streptococcus. Nanomaterials, 2020, 10, 823; doi:10.3390/nano10050823 * Faruck, M. O.; Zhao, L.; Hussein, W. M.; Khalil, Z. G.; Capon, R. J.; Skwarczynski, M.; Toth I. Polyacrylate-peptide antigen conjugate as a single-dose oral vaccine against Group A Streptococcus, Vaccines, 2020,8, 23; doi:10.3390/vaccines8010023. * Azuar, A.; Jin, W.; Mukaida, S.; Hussein, W. M.; Toth I.; Skwarczynski, M. Recent Advances in the Development of Peptide Vaccines and their Delivery Systems against Group A Streptococcus Vaccines,2019, 7, 58; doi:10.3390/vaccines7030058. * Khongkowa, M.; Liu, T-Y.; Bartlett, S.; Hussein, W. M.; Nevagi, R.; Jia, Z.; Monteiro, M. J.; Wells, J. W.; Ruktanonchai, U. R.; Skwarczynski, M.; Toth, I. Liposomal formulation of polyacrylate-peptide conjugate as a new vaccine candidate against cervical cancer. Prec. Nanomed. 2018, 1, 186–196. DOI:10.29016/181025.1 * Skwarczynski, M.; Toth, I. Peptide-based synthetic vaccines Chemical Science,2016, 7, 842 – 854.DOI: 10.1039/c5sc03892h * Goodwin, D.; Varamini, P.; Simerska, P.; D'Occhio, M. J.; Toth, I. Design, synthesis and evaluation of a gonadotropin releasing hormone-based subunit vaccine in rams (Ovis aries). Vaccine 2015, 33, 1453–1458. * Stephenson, R.; Varamini, P.; Butcher, N.; Minchin, R.; Toth, I. Effect of lipidated gonadotropin-releasing hormone peptides on receptor mediated binding and uptake into prostate cancer cells in vitro. Nanomed.-Nanotechnol. Biol. Med. 2014, 10, 1799–1808. * Deng, Z. J.; Liang, M.; Monteiro, M.; Toth, I.; Minchin, R. F. Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation. Nat. Nanotechnol. 2011, 6, 39–44. * Skwarczynski, M.; Zhao, G.; Boer, J. C.; Ozberk, V.; Azuar, A.; Cruz, J. G.; Giddam, A. K.; Khalil, Z. G.; Pandey, M.; Shibu, M. A.; Hussein, W. M.; Nevagi, R.; Batzloff, M. R.; Wells, J. W.; Capon, R. J.; Plebanski, M.; Good, M. F.; Toth, I. Poly(amino acids) as a potent self-adjuvanting delivery system for peptide-based nanovaccines. Sci Adv 2020, 6, eaax2285.

References

External links

* {{DEFAULTSORT:Toth, Istvan Living people Australian chemists Budapest University of Technology and Economics alumni Carleton University alumni 21st-century Australian scientists Academic staff of the University of Queensland Year of birth missing (living people)