Isomorphic Labs Limited is a

London London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...

-based company which uses

artificial intelligence Artificial intelligence (AI) is the capability of computer, computational systems to perform tasks typically associated with human intelligence, such as learning, reasoning, problem-solving, perception, and decision-making. It is a field of re ...

for

drug discovery In the fields of medicine, biotechnology, and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered by identifying the active ingredient from traditional remedies or ...

. Isomorphic Labs was founded by Demis Hassabis, who is the CEO. The company was incorporated on February 24, 2021 and announced on November 4, 2021. It was established under

Alphabet Inc. Alphabet Inc. is an American multinational technology conglomerate holding company headquartered in Mountain View, California. Alphabet is the world's third-largest technology company by revenue, after Amazon and Apple, the largest techno ...

as a spin-off from its AI research lab

DeepMind DeepMind Technologies Limited, trading as Google DeepMind or simply DeepMind, is a British–American artificial intelligence research laboratory which serves as a subsidiary of Alphabet Inc. Founded in the UK in 2010, it was acquired by Go ...

, of which Hassabis is also founder and CEO. The company draws upon DeepMind's

AlphaFold AlphaFold is an artificial intelligence (AI) program developed by DeepMind, a subsidiary of Alphabet, which performs predictions of protein structure. It is designed using deep learning techniques. AlphaFold 1 (2018) placed first in the overall ...

technology, which can be used to predict protein structures in the human body with high accuracy, allowing its researchers to find new target pathways for

drug delivery Drug delivery involves various methods and technologies designed to transport pharmaceutical compounds to their target sites helping therapeutic effect. It involves principles related to drug preparation, route of administration, site-specif ...

. In December 2022, Isomorphic Labs announced its second office location in

Lausanne, Switzerland Lausanne ( , ; ; ) is the capital and largest city of the Swiss French-speaking canton of Vaud, in Switzerland. It is a hilly city situated on the shores of Lake Geneva, about halfway between the Jura Mountains and the Alps, and facing the ...

. In January 2024, Isomorphic Labs partnered with Novartis AG and

Eli Lilly and Company Eli Lilly and Company, Trade name, doing business as Lilly, is an American multinational Medication, pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 count ...

to work together on AI drug discovery and research. In May 2024,

Google DeepMind DeepMind Technologies Limited, trading as Google DeepMind or simply DeepMind, is a British–American artificial intelligence research laboratory which serves as a subsidiary of Alphabet Inc. Founded in the UK in 2010, it was acquired by Goo ...

and Isomorphic Labs announced the release of AlphaFold 3, an artificial intelligence and foundation model platform. Available for free on the AlphaFold server for non-commercial research, the platform was developed by training it with nearly 100,000 known proteins. AlphaFold 3 can predict how proteins fold and the interactions with molecules typically found in drugs such as

ligands In coordination chemistry, a ligand is an ion or molecule with a functional group that binds to a central metal atom to form a coordination complex. The bonding with the metal generally involves formal donation of one or more of the ligand's ...

antibodies An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that caus ...

, which is expected to significantly accelerate drug discovery. In November 2024, preliminary results of CASP16 showed AlphaFold 3-based models did not significantly outperform older methods for predicting protein-ligand interactions. The top performing models in the CASP16 Pose Prediction for Pharma Targets section were ClusPro and CoDock utilizing AlphaFold 2 based predictions, human visual inspection, and manual adjustments. Despite these results, in April 2025 Isomorphic Labs raised $600 Million in its first ever external funding round, led by

Thrive Capital Thrive Capital Management, LLC, commonly Thrive Capital, is an American venture capital firm based in New York City. It focuses on software and internet investments. The firm was founded by Joshua Kushner who is also co-founder of Oscar Health ...

References

External links

* Alphabet Inc. Biotechnology companies Drug discovery companies Artificial intelligence companies Companies based in London 2021 establishments in the United States {{Google-stub