Isocitrate—homoisocitrate dehydrogenase is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
that catalyzes the following two reactions:
*
isocitrate
Isocitric acid is a structural isomer of citric acid. Since citric acid and isocitric acid are structural isomers, they share similar physical and chemical properties. Due to these similar properties, it is difficult to separate the isomers. Salts ...
+
NAD+ 2-oxoglutarate + CO
2 +
NADH
Nicotinamide adenine dinucleotide (NAD) is a coenzyme central to metabolism. Found in all living cells, NAD is called a dinucleotide because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an ade ...
*
homoisocitrate + NAD
+ 2-oxoadipate + CO
2 + NADH + H
+
References
*
EC 1.1.1
{{enzyme-stub