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The interpeduncular fossa is a deep depression of the ventral surface of the
midbrain The midbrain or mesencephalon is the uppermost portion of the brainstem connecting the diencephalon and cerebrum with the pons. It consists of the cerebral peduncles, tegmentum, and tectum. It is functionally associated with vision, hearing, mo ...
between the two cerebal crura. It has been found in humans and macaques, but not in rats or mice, showing that this is a relatively new evolutionary region.


Structure

The interpeduncular fossa is a somewhat rhomboid-shaped area of the base of the brain.


Features

The lateral wall of the interpeduncular fossa bears a groove - the oculomotor sulcus - from which rootlets of the
oculomotor nerve The oculomotor nerve, also known as the third cranial nerve, cranial nerve III, or simply CN III, is a cranial nerve that enters the orbit through the superior orbital fissure and innervates extraocular muscles that enable most movements o ...
emerge from the substance of the brainstem and aggregate into a single fascicle.


Anatomical relations

The
ventral tegmental area The ventral tegmental area (VTA) (tegmentum is Latin for ''covering''), also known as the ventral tegmental area of Tsai, or simply ventral tegmentum, is a group of neurons located close to the midline on the floor of the midbrain. The VTA is th ...
lies at the depth of the interpeduncular fossa.


Boundaries

The interpeduncular fossa is in front by the optic chiasma, behind by the antero-superior surface of the
pons The pons (from Latin , "bridge") is part of the brainstem that in humans and other mammals, lies inferior to the midbrain, superior to the medulla oblongata and anterior to the cerebellum. The pons is also called the pons Varolii ("bridge of ...
, antero-laterally by the converging optic tracts, and postero-laterally by the diverging cerebral peduncles. The floor of interpeduncular fossa, from behind forward, are the posterior perforated substance, corpora mamillaria, tuber cinereum, infundibulum, and
pituitary gland The pituitary gland or hypophysis is an endocrine gland in vertebrates. In humans, the pituitary gland is located at the base of the human brain, brain, protruding off the bottom of the hypothalamus. The pituitary gland and the hypothalamus contr ...
.


Contents

Contents of interpeduncular fossa include
oculomotor nerve The oculomotor nerve, also known as the third cranial nerve, cranial nerve III, or simply CN III, is a cranial nerve that enters the orbit through the superior orbital fissure and innervates extraocular muscles that enable most movements o ...
, and
circle of Willis The circle of Willis (also called Willis' circle, loop of Willis, cerebral arterial circle, and Willis polygon) is a circulatory anastomosis that supplies blood to the brain and surrounding structures in reptiles, birds and mammals, including huma ...
. The basal veins pass alongside the interpeduncular fossa before joining the great cerebral vein.


Clinical significance

The most common locations for neurocutaneous melanosis have occurred along the interpeduncular fossa, ventral brainstem, upper cervical cord, and ventral lumbosacral cord.


See also

* Interpeduncular cistern * Cerebral peduncles


Additional images

File:Human brainstem anterior view 2 description.JPG, Human brainstem anterior view File:Slide7dd.JPG, Interpeduncular fossa. Cerebrum. Deep dissection. Inferior dissection.


References


External links


Diagram at UMich.edu
Cerebrum {{neuroanatomy-stub