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Interdigitating dendritic cell sarcoma is a form of
malignant histiocytosis Malignant histiocytosis is a rare hereditary disease found in the Bernese Mountain Dog and humans, characterized by histiocyte, histiocytic infiltration of the lungs and lymph nodes. The liver, spleen, and central nervous system can also be affec ...
affecting
dendritic cell Dendritic cells (DCs) are antigen-presenting cells (also known as ''accessory cells'') of the mammalian immune system. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system. ...
s. It can present in the
spleen The spleen is an organ found in almost all vertebrates. Similar in structure to a large lymph node, it acts primarily as a blood filter. The word spleen comes .
. It can also present in the
duodenum The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms anterior intestine or proximal intestine ...
.


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Lymphoid-related cutaneous conditions {{neoplasm-stub