Hyannis may refer to:
* Hyannis, Massachusetts, U.S., a village
* Hyannis Port, Massachusetts, U.S., another nearby village
* Hyannis, Nebraska, U.S., a village and county seat
* Hyannis (YTB-817), ''Hyannis'' (YTB-817), a U.S. Navy ''Natick''-class large harbor tug 1973—1997
{{disambiguation, geodis