Heinrich Mückter
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Heinrich Mückter (14 June 1914 – 22 May 1987) was a German medical doctor, pharmacologist and chemist.


World War II

During the Nazi occupation of Poland, Mückter was deputy director of the Kraków Institute for Typhus and Virus Research. Mückter and his colleagues repeatedly experimented on
concentration camp A concentration camp is a prison or other facility used for the internment of political prisoners or politically targeted demographics, such as members of national or ethnic minority groups, on the grounds of national security, or for exploitati ...
prisoners in
Buchenwald Buchenwald (; 'beech forest') was a German Nazi concentration camp established on Ettersberg hill near Weimar, Germany, in July 1937. It was one of the first and the largest of the concentration camps within the Altreich (Old Reich) territori ...
. Many prisoners died as a result of the experiments. Accused by Polish war crimes prosecutors of conducting medical experiments on concentration camp prisoners and Nazi forced labourers, Mückter escaped arrest and fled back to Germany.


Invention of thalidomide

In 1946 Mückter became Head of Research at the
Grünenthal Grünenthal GmbH is a pharmaceutical company headquartered in Aachen in Germany. It was founded in 1946 as Chemie Grünenthal and has been continuously family-owned. The company was the first to introduce penicillin into the German market in t ...
pharmaceutical company, where he further developed the infamous drug
thalidomide Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral administered medication used to treat a number of cancers (e.g., multiple myeloma), graft-versus-host disease, and many skin disorders (e.g., complication ...
which had been synthesized in 1952 by Chemical Industry Basel. Aggressively-marketed as an over-the-counter sleeping pill and remedy for morning sickness in pregnancy, thalidomide was first made available on 1 October 1957, and it became the second best-selling medication in Germany after Bayer Aspirin. Thalidomide was eventually found to cause miscarriages, severe birth defects in babies whose mothers had taken the medication while pregnant, and severe nerve damage. In January 1968, Mückter was put on trial along with other Grünenthal employees. The trial ended abruptly in April 1970 with a settlement. Mückter was never charged in relation to his role in experiments on concentration camp prisoners, nor his role in the thalidomide scandal. He died on 22 May 1987.


References


Der Contergan-Erfinder
1914 births 1987 deaths German pharmacologists 20th-century German chemists {{Nazi Germany-stub