Health Effects Of Alcohol
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Alcohol Alcohol may refer to: Common uses * Alcohol (chemistry), a class of compounds * Ethanol, one of several alcohols, commonly known as alcohol in everyday life ** Alcohol (drug), intoxicant found in alcoholic beverages ** Alcoholic beverage, an alco ...
(also known as
ethanol Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the ps ...
) has a number of effects on
health Health has a variety of definitions, which have been used for different purposes over time. In general, it refers to physical and emotional well-being, especially that associated with normal functioning of the human body, absent of disease, p ...
. Short-term effects of alcohol consumption include intoxication and
dehydration In physiology, dehydration is a lack of total body water that disrupts metabolic processes. It occurs when free water loss exceeds intake, often resulting from excessive sweating, health conditions, or inadequate consumption of water. Mild deh ...
. Long-term effects of alcohol include changes in the metabolism of the
liver The liver is a major metabolic organ (anatomy), organ exclusively found in vertebrates, which performs many essential biological Function (biology), functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of var ...
and
brain The brain is an organ (biology), organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head (cephalization), usually near organs for ...
, with increased risk of several types of cancer and
alcohol use disorder Alcoholism is the continued drinking of alcohol despite it causing problems. Some definitions require evidence of dependence and withdrawal. Problematic use of alcohol has been mentioned in the earliest historical records. The World Hea ...
. Alcohol intoxication affects the brain, causing slurred speech, clumsiness, and delayed reflexes. There is an increased risk of developing an alcohol use disorder for teenagers while their brain is still developing. Adolescents who drink have a higher probability of injury including death. Observational studies suggest a correlation between low to moderate alcohol consumption and cardiovascular protective effects. Several studies and meta-analyses have shown a reduction in overall mortality among light to moderate alcohol drinkers compared to lifetime abstainers. A statement from ''The Lancet'' in 2022, based on the 2020 Global Burden of Disease Study, noted that for adults over 40 consuming small amounts of alcohol may reduce risks for cardiovascular disease, stroke, and diabetes. Even light to moderate alcohol consumption can have negative effects on health, such as by increasing a person's risk of developing several
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
s. A 2014
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
(WHO) report found that harmful alcohol consumption caused about 3.3 million deaths annually worldwide. Negative effects are related to the amount consumed with no safe lower limit seen. Some nations have introduced alcohol packaging warning messages that inform consumers about
alcohol and cancer Alcohol may refer to: Common uses * Alcohol (chemistry), a class of compounds * Ethanol, one of several alcohols, commonly known as alcohol in everyday life ** Alcohol (drug), intoxicant found in alcoholic beverages ** Alcoholic beverage D ...
, as well as
fetal alcohol syndrome Fetal alcohol spectrum disorders (FASDs) are a group of conditions that can occur in a person who is exposed to alcohol during gestation. FASD affects 1 in 20 Americans, but is highly misdiagnosed and underdiagnosed. The several forms of the ...
. There are several potential ways for light alcohol drinkers to reduce their cancer risk. Research suggests that dietary intake of folate, in amounts commonly found in daily multivitamins, may help protect women from the increased risk of breast cancer associated with light alcohol consumption. Additionally, two large U.S.-based studies on health professionals found no increased cancer risk from light to moderate alcohol consumption in men who do not smoke. Some observational studies suggest a potential association between alcohol consumption and a decreased risk of certain cancers, such as kidney cancer, thyroid cancer, and non-Hodgkin lymphoma. Multiple prospective studies suggest a protective effect of light to moderate alcohol consumption on cardiovascular health for both men and women. Several mechanisms have been proposed to explain this association. Additionally, alcohol may reduce the risk of clot formation, which can contribute to heart attacks and strokes, and lower the risk of developing diabetes. A 2022 statement from ''
The Lancet ''The Lancet'' is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. The journal publishes ...
'', based on its 2020 Global Burden of Disease Study, said that the health risks associated with alcohol consumption vary by age and region, and that for those over age 40, "consuming a small amount of alcohol ... can provide some health benefits, such as reducing the risk of cardiovascular disease, stroke, and diabetes."


Short-term effects

The short-term effects of alcohol consumption range from a decrease in anxiety and motor skills at lower doses to unconsciousness,
anterograde amnesia In neurology, anterograde amnesia is the inability to create new memories after an event that caused amnesia, leading to a partial or complete inability to recall the recent past, while long-term memories from before the event remain intact. Thi ...
, and
central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity o ...
depression at higher doses.
Cell membrane The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extr ...
s are highly permeable to alcohol, so once alcohol is in the bloodstream it can diffuse into nearly every cell in the body. The
concentration In chemistry, concentration is the abundance of a constituent divided by the total volume of a mixture. Several types of mathematical description can be distinguished: '' mass concentration'', '' molar concentration'', '' number concentration'', ...
of alcohol in
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
is measured via
blood alcohol content Blood alcohol content (BAC), also called blood alcohol concentration or blood alcohol level, is a measurement of alcohol intoxication used for legal or medical purposes. BAC is expressed as mass of alcohol per volume of blood. In US and many i ...
(BAC). The amount and circumstances of consumption play a large part in determining the extent of intoxication; for example, eating a heavy meal before alcohol consumption causes alcohol to absorb more slowly. Hydration also plays a role, especially in determining the extent of
hangover A hangover is the experience of various unpleasant physiological and psychological effects usually following the consumption of alcohol (beverage), alcohol, such as wine, beer, and liquor. Hangovers can last for several hours or for more than ...
s. After
binge drinking Binge drinking, or heavy episodic drinking, is drinking alcoholic beverages with an intention of becoming intoxicated by heavy consumption of alcohol over a short period of time, but definitions vary considerably. Binge drinking is a style of ...
,
unconsciousness Unconsciousness is a state in which a living individual exhibits a complete, or near-complete, inability to maintain an awareness of self and environment or to respond to any human or environmental stimulus. Unconsciousness may occur as the r ...
can occur and extreme levels of consumption can lead to
alcohol poisoning Alcohol intoxication, commonly described in higher doses as drunkenness or inebriation, and known in overdose as alcohol poisoning, is the behavior and physical effects caused by recent consumption of alcohol. The technical term ''intoxication ...
and death (a concentration in the blood stream of 0.40% will kill half of those affected). Alcohol may also cause death indirectly, by
asphyxiation Asphyxia or asphyxiation is a condition of deficient supply of oxygen to the body which arises from abnormal breathing. Asphyxia causes generalized hypoxia, which affects all the tissues and organs, some more rapidly than others. There are ...
from
vomit Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregna ...
. Alcohol disrupts normal sleep patterns thereby reducing sleep quality and can greatly exacerbate sleep problems. During
abstinence Abstinence is the practice of self-enforced restraint from indulging in bodily activities that are widely experienced as giving pleasure. Most frequently, the term refers to sexual abstinence, but it can also mean abstinence from alcohol (drug), ...
, residual disruptions in sleep regularity and sleep patterns are the greatest predictors of
relapse In internal medicine, relapse or recidivism is a recurrence of a past (typically medical) condition. For example, multiple sclerosis and malaria often exhibit peaks of activity and sometimes very long periods of dormancy, followed by relapse or r ...
. Heavy alcohol consumption while in a hunger state can cause
alcoholic ketoacidosis Alcoholic ketoacidosis (AKA) is a specific group of symptoms and metabolic state related to alcohol use. Symptoms often include abdominal pain, vomiting, agitation, a fast respiratory rate, and a specific "fruity" smell. Consciousness is generall ...
, a life-threatening metabolic derailment. The
median lethal dose In toxicology, the median lethal dose, LD50 (abbreviation for " lethal dose, 50%"), LC50 (lethal concentration, 50%) or LCt50 is a toxic unit that measures the lethal dose of a given substance. The value of LD50 for a substance is the dose re ...
of alcohol in test animals is a
blood alcohol content Blood alcohol content (BAC), also called blood alcohol concentration or blood alcohol level, is a measurement of alcohol intoxication used for legal or medical purposes. BAC is expressed as mass of alcohol per volume of blood. In US and many i ...
of 0.45%. This is about six times the level of ordinary intoxication (0.08%), but
vomiting Vomiting (also known as emesis, puking and throwing up) is the forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pre ...
or unconsciousness may occur much sooner in people who have a low tolerance for alcohol.Meyer, Jerold S. and Linda F. Quenzer. Psychopharmacology: Drugs, the Brain, and Behavior. Sinauer Associates, Inc.: Sunderland, Massachusetts. 2005. Page 228. The high tolerance of chronic heavy drinkers may allow some of them to remain conscious at levels above 0.40%, although serious health hazards are incurred at this level. Alcohol also limits the production of
vasopressin Mammalian vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized from the ''AVP'' gene as a peptide prohormone in neurons in the hypothalamus, and is converted to AVP. It ...
(antidiuretic hormone) from the
hypothalamus The hypothalamus (: hypothalami; ) is a small part of the vertebrate brain that contains a number of nucleus (neuroanatomy), nuclei with a variety of functions. One of the most important functions is to link the nervous system to the endocrin ...
and the secretion of this
hormone A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physio ...
from the
posterior pituitary The posterior pituitary (or neurohypophysis) is the posterior lobe of the pituitary gland which is part of the endocrine system. Unlike the anterior pituitary, the posterior pituitary is not glandular, but largely a collection of axonal projec ...
gland. This is what causes severe dehydration when alcohol is consumed in large amounts. It also causes a high concentration of water in the
urine Urine is a liquid by-product of metabolism in humans and many other animals. In placental mammals, urine flows from the Kidney (vertebrates), kidneys through the ureters to the urinary bladder and exits the urethra through the penile meatus (mal ...
and vomit, and the intense thirst that goes along with a
hangover A hangover is the experience of various unpleasant physiological and psychological effects usually following the consumption of alcohol (beverage), alcohol, such as wine, beer, and liquor. Hangovers can last for several hours or for more than ...
.


Long-term effects

According to the World Health Organization's 2018 Global Status Report on Alcohol and Health, there are more than 3 million people who die from the harmful effects of alcohol each year, which amounts to more than 5% of the burden of disease worldwide. The US
National Institutes of Health The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Service ...
similarly estimates that 3.3 million deaths (5.9% of all deaths) were believed to be due to alcohol each year. As per WHO June 2024 report on Alcohol, around 2.6 million deaths were caused by alcohol consumption in 2019 worldwide. Guidelines in the US and the UK advise that ''if'' people choose to drink, they should drink modestly. Even light and moderate alcohol consumption increases a person's cancer risk, especially the risk of developing squamous cell carcinoma of the esophagus, cancers of the mouth and tongue,
liver cancer Liver cancer, also known as hepatic cancer, primary hepatic cancer, or primary hepatic malignancy, is cancer that starts in the liver. Liver cancer can be primary in which the cancer starts in the liver, or it can be liver metastasis, or secondar ...
, and
breast cancer Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipp ...
. Using alcohol, especially together with
tobacco Tobacco is the common name of several plants in the genus '' Nicotiana'' of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the ...
, is a major risk factor for
head and neck cancer Head and neck cancer is a general term encompassing multiple cancers that can develop in the head and neck region. These include cancers of the mouth, tongue, gums and lips (oral cancer), voice box ( laryngeal), throat ( nasopharyngeal, orophary ...
. 72% of head and neck cancer cases are caused by using both alcohol and tobacco. This rises to 89% when looking specifically at
laryngeal cancer Laryngeal cancer is a kind of cancer that can develop in any part of the larynx (voice box). It is typically a squamous-cell carcinoma, reflecting its origin from the epithelium of the larynx. The prognosis is affected by the location of the tumo ...
. A systematic analysis of data from the
Global Burden of Disease Study The Global Burden of Disease Study (GBD) is a comprehensive regional and global research program of disease burden that assesses mortality and disability from major diseases, injuries, and risk factors. GBD is a collaboration of over 12,000 rese ...
, which was an
observational study In fields such as epidemiology, social sciences, psychology and statistics, an observational study draws inferences from a sample (statistics), sample to a statistical population, population where the dependent and independent variables, independ ...
, found that long-term consumption of any amount of alcohol is associated with an increased risk of death in all people, and that even moderate consumption appears to be risky. Similar to prior analyses, it found an apparent benefit for older women in reducing the risks of death from ischemic heart disease and from
diabetes mellitus Diabetes mellitus, commonly known as diabetes, is a group of common endocrine diseases characterized by sustained hyperglycemia, high blood sugar levels. Diabetes is due to either the pancreas not producing enough of the hormone insulin, or th ...
, but unlike prior studies it found those risks cancelled by an apparent increased risk of death from breast cancer and other causes. A 2016 systematic review and meta-analysis found that moderate ethanol consumption brought no mortality benefit compared with lifetime abstention from ethanol consumption. Risk is greater in younger people due to heavy episodic drinking which may result in violence or accidents. Long-term heavy use of alcohol damages nearly every organ and system in the body. Risks include
alcohol use disorder Alcoholism is the continued drinking of alcohol despite it causing problems. Some definitions require evidence of dependence and withdrawal. Problematic use of alcohol has been mentioned in the earliest historical records. The World Hea ...
,
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues a ...
, chronic pancreatitis,
alcoholic liver disease Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosi ...
(e.g., permanent liver scarring) and several types of
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
. In addition, damage to the
central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity o ...
and
peripheral nervous system The peripheral nervous system (PNS) is one of two components that make up the nervous system of Bilateria, bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside t ...
(e.g., painful
peripheral neuropathy Peripheral neuropathy, often shortened to neuropathy, refers to damage or disease affecting the nerves. Damage to nerves may impair sensation, movement, gland function, and/or organ function depending on which nerve fibers are affected. Neuropa ...
) can occur from chronic alcohol misuse. The developing adolescent brain is particularly vulnerable to the toxic effects of alcohol. A systematic analysis found in 2022 that the level of alcohol consumption recommended by many existing guidelines is too high in particular for young people in all regions.


DNA damage

Acetaldehyde Acetaldehyde (IUPAC systematic name ethanal) is an organic compound, organic chemical compound with the chemical formula, formula , sometimes abbreviated as . It is a colorless liquid or gas, boiling near room temperature. It is one of the most ...
is produced when cells process ethanol. Acetaldehyde, is a DNA damaging metabolite that can interact with DNA to crosslink the two strands of the DNA duplex. The mechanisms the cells use for repairing these crosslinks are error prone, thus leading to
mutation In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, ...
s that in the long term can cause cancer.


Pregnancy

Medical organizations strongly discourage drinking alcohol during pregnancy. Alcohol passes easily from the mother's bloodstream through the
placenta The placenta (: placentas or placentae) is a temporary embryonic and later fetal organ that begins developing from the blastocyst shortly after implantation. It plays critical roles in facilitating nutrient, gas, and waste exchange between ...
and into the bloodstream of the fetus, which interferes with brain and organ development. Alcohol can affect the fetus at any stage during pregnancy, but the level of risk depends on the amount and frequency of alcohol consumed. Regular heavy drinking and heavy episodic drinking (also called binge drinking), entailing four or more standard alcoholic drinks (a pint of beer or 50 ml drink of a spirit such as
whisky Whisky or whiskey is a type of liquor made from Fermentation in food processing, fermented grain mashing, mash. Various grains (which may be Malting, malted) are used for different varieties, including barley, Maize, corn, rye, and wheat. Whisky ...
corresponds to about two units of alcohol) on any one occasion, pose the greatest risk for harm, but lesser amounts can cause problems as well. There is no known safe amount or safe time to drink during pregnancy, and the U.S.
Centers for Disease Control and Prevention The Centers for Disease Control and Prevention (CDC) is the National public health institutes, national public health agency of the United States. It is a Federal agencies of the United States, United States federal agency under the United S ...
recommends complete abstinence for women who are pregnant, trying to become pregnant, or are sexually active and not using birth control. Prenatal alcohol exposure can lead to
fetal alcohol spectrum disorders Fetal alcohol spectrum disorders (FASDs) are a group of conditions that can occur in a person who is exposed to alcohol during gestation. FASD affects 1 in 20 Americans, but is highly misdiagnosed and underdiagnosed. The several forms of the ...
(FASDs). The most severe form of FASD is fetal alcohol syndrome (FAS). Problems associated with FASD include abnormal facial development, low birth weight,
stunted growth Stunted growth, also known as stunting or linear growth failure, is defined as impaired growth and development manifested by low height-for-age. Stunted growth is often caused by malnutrition, and can also be caused by Endogeny (biology), endogeno ...
, small head size, delayed or uncoordinated
motor skill A motor skill is a function that involves specific movements of the motor system, body's muscles to perform a certain task. These tasks could include walking, running, or riding a bike. In order to perform this skill, the body's nervous system, m ...
s,
hearing Hearing, or auditory perception, is the ability to perceive sounds through an organ, such as an ear, by detecting vibrations as periodic changes in the pressure of a surrounding medium. The academic field concerned with hearing is auditory sci ...
or
vision problems Visual or vision impairment (VI or VIP) is the partial or total inability of visual perception. In the absence of treatment such as corrective eyewear, assistive devices, and medical treatment, visual impairment may cause the individual difficul ...
,
learning disabilities Learning disability, learning disorder, or learning difficulty (British English) is a condition in the brain that causes difficulties comprehending or processing information and can be caused by several different factors. Given the "difficulty ...
, behavior problems, and inappropriate
social skill A social skill is any competence facilitating interaction and communication with others where social rules and relations are created, communicated, and changed in verbal and nonverbal ways. The process of learning these skills is called socia ...
s compared to same-age peers. Those affected are more likely to have trouble in school, legal problems, participate in high-risk behaviors, and develop
substance use disorder Substance use disorder (SUD) is the persistent use of drugs despite substantial harm and adverse consequences to self and others. Related terms include ''substance use problems'' and ''problematic drug or alcohol use''. Along with substance-ind ...
s like excessive drinking themselves.


Cardiovascular disease

In 2010, a systematic review reported that moderate consumption of alcohol does not cause harm to people with cardiovascular disease. However, the authors did not encourage people to start drinking alcohol in the hope of any benefit. In a 2018 study on 599,912 drinkers, a roughly linear association was found with alcohol consumption and a higher risk of
stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...
,
coronary artery disease Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...
excluding
myocardial infarction A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom ...
,
heart failure Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to Cardiac cycle, fill with and pump blood. Although symptoms vary based on which side of the heart is affected, HF ...
, fatal hypertensive disease, and fatal
aortic aneurysm An aortic aneurysm is an enlargement (dilatation) of the aorta to greater than 1.5 times normal size. Typically, there are no symptoms except when the aneurysm dissects or ruptures, which causes sudden, severe pain in the abdomen and lower back ...
, even for moderate drinkers. The
American Heart Association The American Heart Association (AHA) is a nonprofit organization in the United States that funds cardiovascular medical research, educates consumers on healthy living and fosters appropriate Heart, cardiac care in an effort to reduce disability ...
states that people who are currently non-drinkers should not start drinking alcohol.


Insulin response

Alcohol is known to potentiate the insulin response of the human body to
glucose Glucose is a sugar with the Chemical formula#Molecular formula, molecular formula , which is often abbreviated as Glc. It is overall the most abundant monosaccharide, a subcategory of carbohydrates. It is mainly made by plants and most algae d ...
, which, in essence, "instructs" the body to convert consumed carbohydrates into fat and to suppress carbohydrate and fat oxidation. Ethanol is directly processed in the liver to
acetyl CoA Acetyl-CoA (acetyl coenzyme A) is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism. Its main function is to deliver the acetyl group to the citric acid cycle (Krebs cycle) to be oxidized fo ...
, the same intermediate product as in glucose metabolism. Because ethanol is mostly metabolized and consumed by the liver, chronic excessive use can lead to
fatty liver Fatty liver disease (FLD), also known as hepatic steatosis and steatotic liver disease (SLD), is a condition where excess fat builds up in the liver. Often there are no or few symptoms. Occasionally there may be tiredness or pain in the upper r ...
. This leads to a chronic inflammation of the liver and eventually
alcoholic liver disease Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosi ...
. Alcohol consumption can cause
hypoglycemia Hypoglycemia (American English), also spelled hypoglycaemia or hypoglycæmia (British English), sometimes called low blood sugar, is a fall in blood sugar to levels below normal, typically below 70 mg/dL (3.9 mmol/L). Whipple's tria ...
in diabetics on certain medications, such as
insulin Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabol ...
or
sulfonylurea Sulfonylureas or sulphonylureas are a class of organic compounds used in medicine and agriculture. The functional group consists of a sulfonyl group (-S(=O)2) with its sulphur atom bonded to a nitrogen atom of a ureylene group (N,N-dehydrourea ...
, by blocking
gluconeogenesis Gluconeogenesis (GNG) is a metabolic pathway that results in the biosynthesis of glucose from certain non-carbohydrate carbon substrates. It is a ubiquitous process, present in plants, animals, fungi, bacteria, and other microorganisms. In verte ...
. Alcoholic beverages show a lower
satiety value Satiety value is the degree at which food gives a human the feeling of satiety per calorie. The concept of the Satiety Value and Satiety Index was developed by Australians, Australian researcher and doctor, Susanna Holt. Highest satiety value is ex ...
per calorie.


Breastfeeding

The UK
National Health Service The National Health Service (NHS) is the term for the publicly funded health care, publicly funded healthcare systems of the United Kingdom: the National Health Service (England), NHS Scotland, NHS Wales, and Health and Social Care (Northern ...
states that "an occasional drink is unlikely to harm" a breastfed baby, and recommends consumption of "no more than one or two units of alcohol once or twice a week" for breastfeeding mothers (where a pint of beer or 50 ml drink of a spirit such as whisky corresponds to about ''two'' units of alcohol). The NHS also recommends to wait for a couple of hours before breastfeeding or express the milk into a bottle before drinking. Researchers have shown that intoxicated breastfeeding reduces the average milk expression but poses no immediate threat to the child as the amount of transferred alcohol is insignificant.


Mental health


Mental disorders

Alcohol misuse often coincides with mental health conditions. Many individuals struggling with psychiatric disorders also experience problematic drinking behaviors.


Spiritual use of alcohol

Most religions prohibit or advise against alcohol use. However, spiritual use of alcohol is found in some religions and schools with esoteric influences, including the Hindu tantra sect
Aghori The Aghori (from , ) are a Hindu monastic order of ascetic Shaivite sadhus based in Uttar Pradesh, India. They are the only surviving sect derived from the '' Kāpālika'' tradition, a Tantric, non-Puranic form of Shaivism which originated ...
, in the
Sufi Sufism ( or ) is a mysticism, mystic body of religious practice found within Islam which is characterized by a focus on Islamic Tazkiyah, purification, spirituality, ritualism, and Asceticism#Islam, asceticism. Practitioners of Sufism are r ...
Bektashi Order Bektashism (, ) is a Sufi order of Islam that evolved in 13th-century western Anatolia and became widespread in the Ottoman Empire. It is named after the ''walī'' "saint" Haji Bektash Veli, with adherents called Bektashis. The Bektashi co ...
and
Alevi Alevism (; ; ) is a syncretic heterodox Islamic tradition, whose adherents follow the mystical Islamic teachings of Haji Bektash Veli, who taught the teachings of the Twelve Imams, whilst incorporating some traditions from shamanism. Differing ...
Jem ceremonies, in the Japanese religion
Shinto , also called Shintoism, is a religion originating in Japan. Classified as an East Asian religions, East Asian religion by Religious studies, scholars of religion, it is often regarded by its practitioners as Japan's indigenous religion and as ...
, by the new religious movement
Thelema Thelema () is a Western esotericism, Western esoteric and occult social or spiritual philosophy and a new religious movement founded in the early 1900s by Aleister Crowley (1875–1947), an English writer, mystic, occultist, and ceremonial ma ...
, in
Vajrayana Buddhism ''Vajrayāna'' (; 'vajra vehicle'), also known as Mantrayāna ('mantra vehicle'), Guhyamantrayāna ('secret mantra vehicle'), Tantrayāna ('tantra vehicle'), Tantric Buddhism, and Esoteric Buddhism, is a Mahāyāna Buddhist tradition that emp ...
, and in Vodou faith of Haiti.


Alcohol education

Alcohol education is the practice of disseminating information about the effects of alcohol on health, as well as society and the family unit. It was introduced into the public schools by
temperance organizations The temperance movement is a social movement promoting temperance or total abstinence from consumption of alcoholic beverages. Participants in the movement typically criticize alcohol intoxication or promote teetotalism, and its leaders emphasi ...
such as the
Woman's Christian Temperance Union The Woman's Christian Temperance Union (WCTU) is an international temperance organization. It was among the first organizations of women devoted to social reform with a program that "linked the religious and the secular through concerted and far ...
in the late 19th century. Initially, alcohol education focused on how the consumption of alcoholic beverages affected society, as well as the family unit. In the 1930s, this came to also incorporate education pertaining to alcohol's effects on health. Organizations such as the
National Institute on Alcohol Abuse and Alcoholism The National Institute on Alcohol Abuse and Alcoholism (NIAAA), as part of the U.S. National Institutes of Health, supports and conducts biomedical and Behavioral research, behavioural research on the causes, consequences, treatment, and prevent ...
in the United States were founded to promulgate alcohol education alongside those of the
temperance movement The temperance movement is a social movement promoting Temperance (virtue), temperance or total abstinence from consumption of alcoholic beverages. Participants in the movement typically criticize alcohol intoxication or promote teetotalism, and ...
, such as the
American Council on Alcohol Problems The Anti-Saloon League, now known as the American Council on Addiction and Alcohol Problems, is an organization of the temperance movement in the United States. Founded in 1893 in Oberlin, Ohio, it was a key component of the Progressive Era, an ...
.


Alcohol expectations

Alcohol expectations are
belief A belief is a subjective Attitude (psychology), attitude that something is truth, true or a State of affairs (philosophy), state of affairs is the case. A subjective attitude is a mental state of having some Life stance, stance, take, or opinion ...
s and attitudes that people have about the effects they will experience when drinking alcoholic beverages. ''Alcohol expectancy theory'' posits that drinking behaviors are driven by these expectations, and the individual may be motivated to drink to obtain desired alcohol effects or, alternatively, motivated to refrain from drinking due to the expectation of undesirable effects. Intoxication does have real physiological effects, such as altering a drinker's perception of space and time, reducing psychomotor skills, and disrupting
equilibrium Equilibrium may refer to: Film and television * ''Equilibrium'' (film), a 2002 science fiction film * '' The Story of Three Loves'', also known as ''Equilibrium'', a 1953 romantic anthology film * "Equilibrium" (''seaQuest 2032'') * ''Equilibr ...
. But some effects and the degree of the effects that are attributed to alcohol can be due to the expectations rather than the substance itself, similar to the
placebo effect A placebo ( ) can be roughly defined as a sham medical treatment. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures. Placebos are used in randomized clinical trials ...
. For example, in a laboratory study, men acted more aggressive when they believed their drink contained alcohol, even when it was plain
tonic water Tonic water is a carbonated soft drink in which quinine is dissolved. Originally used as a prophylactic against malaria, modern tonic water typically has a significantly lower quinine content and is often more sweetened than the original medic ...
. They also were less aggressive when they believed they were consuming a non-alcoholic drink, even if it contained alcohol. This shows that aggression is a result of expectations. The study has been replicated. Another study found that those who believed that intoxication leads to
sexual behavior Human sexual activity, human sexual practice or human sexual behaviour is the manner in which humans experience and express their sexuality. People engage in a variety of sexual acts, ranging from activities done alone (e.g., masturbation) t ...
, rowdy behavior, and aggression tended to act that way when intoxicated. But similarly the belief that intoxication leads to relaxation and tranquil behavior was self-fulfilling. As a third example, some societies expect that drinking alcohol will cause disinhibition. However, in societies in which the people do not expect that alcohol will disinhibit, intoxication seldom leads to disinhibition and bad behavior. Common positive alcohol outcome expectancies include tension reduction, heightened sociability, increased courage, and enhanced sexual experiences, whereas common negative alcohol outcome expectancies include cognitive and behavioral impairment, risk and aggression, as well as worsened self-perception. The manner and degree to which alcohol expectations interact with the physiological short-term effects of alcohol, resulting in specific behaviors, is unclear. Alcohol expectations vary within a society, and people tend to conform to social expectations.


Drug treatment programs

Most addiction treatment programs encourage people with drinking problems to see themselves as having a chronic, relapsing disease that requires a lifetime of attendance at 12-step meetings to keep in check.


Alcohol use disorder

The data on global alcohol consumption in 2019 shows that an estimated 400 million people aged 15 years and older live with alcohol use disorders, and an estimated 209 million live with alcohol dependence.


Alcohol misuse prevention programs of the World Health Organization

More than 200 injuries and disease conditions can be caused by alcohol misuse. It is a causative agent influencing maternal health and development, noncommunicable diseases (including cancer and cardiovascular diseases), injuries, violence, mental health, and infectious diseases such as
tuberculosis Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, is a contagious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can al ...
and
HIV/AIDS The HIV, human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a Preventive healthcare, pr ...
. Harmful use of alcohol has been identified as a global health issue, and its management is a priority in the 2030 Agenda for Sustainable Development issued by the
United Nations The United Nations (UN) is the Earth, global intergovernmental organization established by the signing of the Charter of the United Nations, UN Charter on 26 June 1945 with the stated purpose of maintaining international peace and internationa ...
in 2015. In 2018, the WHO launched the "SAFER" initiative (an acronym defined from the list of planned actions give below), to decrease the number of deaths, diseases and injuries caused by alcohol misuse. Using a set of WHO tools and resources, SAFER was planned to concentrate on the interventions listed below to reduce and prevent alcohol misuse. The list of interventions were selected for prioritization based on cost effectiveness: * Strengthen restrictions on alcohol availability. * Advance and enforce drink driving countermeasures. * Facilitate access to screening, brief interventions, and treatment. * Enforce bans or comprehensive restrictions on alcohol advertising, sponsorship, and promotion. * Raise prices on alcohol through
excise taxes file:Lincoln Beer Stamp 1871.JPG, upright=1.2, 1871 U.S. Revenue stamp for 1/6 barrel of beer. Brewers would receive the stamp sheets, cut them into individual stamps, cancel them, and paste them over the Bunghole, bung of the beer barrel so when ...
and pricing policies.


Recommended maximum intake

Binge drinking has been a significant issue in the United Kingdom. Advice on weekly consumption levels is often avoided in the UK. Official advice from the National Health Service is that for all genders, regularly drinking more than 14 units of alcohol a week "risks damaging your health". Since 1995, the UK government has advised that regular consumption of three to four units (one unit equates to 10 mL of pure ethanol) a day for men and or two to three units for women, would not pose significant health risks. However, consistently drinking more than four units a day (for men) and three units (women) is not advisable. Previously (from 1992 until 1995), the advice was that men should drink no more than 21 units per week, and women no more than 14. (The difference between the sexes was due to the typically lower weight and water-to-body-mass ratio of women.) This was changed because a government study showed that many people were in effect "saving up" their units and using them at the end of the week, a phenomenon referred to as
binge drinking Binge drinking, or heavy episodic drinking, is drinking alcoholic beverages with an intention of becoming intoxicated by heavy consumption of alcohol over a short period of time, but definitions vary considerably. Binge drinking is a style of ...
. ''
The Times ''The Times'' is a British Newspaper#Daily, daily Newspaper#National, national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its modern name on 1 January 1788. ''The Times'' and its si ...
'' reported in October 2007 that these limits had been "plucked out of the air" and had no scientific basis.


Sobriety

Sobriety is the condition of not having any measurable levels, or effects from mood-altering drugs. According to WHO "Lexicon of alcohol and drug terms", sobriety is continued abstinence from psychoactive drug use. Sobriety is also considered to be the natural state of a human being given at a birth. In a treatment setting, sobriety is the achieved goal of independence from consuming or craving mind-altering substances. As such, sustained abstinence is a prerequisite for sobriety. Early in abstinence, residual effects of mind-altering substances can preclude sobriety. These effects are labeled post-acute-withdrawal syndrome (PAWS). Someone who abstains, but has a latent desire to resume use, is not considered truly sober. An abstainer may be subconsciously motivated to resume drug use, but for a variety of reasons, abstains (e.g. such as a medical or legal concern precluding use). Sobriety has more specific meanings within specific contexts, such as the culture of
Alcoholics Anonymous Alcoholics Anonymous (AA) is a global, peer-led Mutual aid, mutual-aid fellowship focused on an abstinence-based recovery model from alcoholism through its spiritually inclined twelve-step program. AA's Twelve Traditions, besides emphasizing anon ...
, other 12 step programs, law enforcement, and some schools of psychology. In some cases, sobriety implies achieving "life balance".


Injury and deaths

Injury Injury is physiological damage to the living tissue of any organism, whether in humans, in other animals, or in plants. Injuries can be caused in many ways, including mechanically with penetration by sharp objects such as teeth or with ...
is defined as physical damage or harm that is done or sustained. The potential of injuring oneself or others can be increased after consuming alcohol due to the certain short term effects related to the substance such as lack of coordination, blurred vision, and slower reflexes to name a few. Due to these effects the most common injuries include head, fall, and vehicle-related injuries. A study was conducted of patients admitted to the Ulster Hospital in Northern Ireland with fall related injuries. They found that 113 of those patients admitted to that hospital during that had consumed alcohol recently and that the injury severity was higher for those that had consumed alcohol compared to those that had not. Another study showed that 21% of patients admitted to the Emergency Department of the
Bristol Royal Infirmary The Bristol Royal Infirmary (BRI) is a large teaching hospital in the centre of Bristol, England. It has links with the nearby University of Bristol and the Faculty of Health and Social Care at the University of the West of England, also in Brist ...
had either direct or indirect alcohol related injuries. If these figures are extrapolated it shows that the estimated number of patients with alcohol related injuries are over 7,000 during the year at this emergency department alone. In the United States alcohol resulted in about 88,000 deaths in 2010. The
World Health Organization The World Health Organization (WHO) is a list of specialized agencies of the United Nations, specialized agency of the United Nations which coordinates responses to international public health issues and emergencies. It is headquartered in Gen ...
calculated that more than 3 million people, mostly men, died as a result of harmful use of alcohol in 2016. This was about 13.5% of the total deaths of people between 20 and 39. More than 5% of the global disease burden was caused by the harmful use of alcohol. There are even higher estimates for Europe. In 2019, total of 298,000 deaths from alcohol-related road crashes were registered, out of which 156,000 deaths were caused by someone else’s drinking.


Flaming drink

A
flaming drink A flaming drink is a cocktail or other mixed drink that contains flammable, high-proof alcohol, which is ignited before consumption. The alcohol may be an integral part of the drink, or it may be floated as a thin layer across the top of the dr ...
is often ignited for aesthetic and entertainment purposes. However, bars have been shut down specifically due to failure to follow fire codes and reckless endangerment of patrons. Bartenders have also suffered burns from flaming drinks.


Genetic differences


Alcohol flush and respiratory reactions

Alcohol flush reaction is a condition in which an individual's face or body experiences flushes (appears red) or blotches as a result of an accumulation of
acetaldehyde Acetaldehyde (IUPAC systematic name ethanal) is an organic compound, organic chemical compound with the chemical formula, formula , sometimes abbreviated as . It is a colorless liquid or gas, boiling near room temperature. It is one of the most ...
, a metabolic byproduct of the catabolic metabolism of alcohol. It is best known as a condition that is experienced by people of Asian descent. According to the analysis by HapMap Project, the rs671 allele of the ALDH2 gene responsible for the flush reaction is rare among Europeans and Africans, and it is very rare among Mexican-Americans. 30% to 50% of people of Chinese and Japanese ancestry have at least one ALDH*2 allele. The rs671 form of ALDH2, which accounts for most incidents of alcohol flush reaction worldwide, is native to East Asia and most common in southeastern China. It most likely originated among Han Chinese in central China, and it appears to have been positively selected in the past. Another analysis correlates the rise and spread of rice cultivation in Southern China with the spread of the allele. The reasons for this positive selection are unknown, but the hypothesis that elevated concentrations of acetaldehyde may have conferred protection against certain parasitic infections, such as ''
Entamoeba histolytica ''Entamoeba histolytica'' is an anaerobic organism, anaerobic parasitic amoebozoan, part of the genus ''Entamoeba''. Predominantly infecting humans and other primates causing amoebiasis, ''E. histolytica'' is estimated to infect about 35-50 mil ...
'' have been suggested. The same SNP allele of ALDH2, also termed glu487lys, and the abnormal accumulation of acetaldehyde following the drinking of alcohol, is associated with the alcohol-induced respiratory reactions of
rhinitis Rhinitis, also known as coryza, is irritation and inflammation of the mucous membrane inside the nose. Common symptoms are a stuffy nose, runny nose, sneezing, and post-nasal drip. The inflammation is caused by viruses, bacteria, irritant ...
and
asthma Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wh ...
that occur in Eastern Asian populations.


Alcohol and Native Americans

Compared with the United States population in general, the Native American population is much more susceptible to alcohol use disorder and related diseases and deaths. From 2006 to 2010, alcohol-attributed deaths accounted for 11.7 percent of all Native American deaths, more than twice the rates of the general U.S. population. The median alcohol-attributed death rate for Native Americans (60.6 per 100,000) was twice as high as the rate for any other racial or ethnic group. Males are affected disproportionately more by alcohol-related conditions than females. Native American and Native Alaskan youth are far more likely to experiment with alcohol at a younger age than non-Native youth. Low
self-esteem Self-esteem is confidence in one's own worth, abilities, or morals. Self-esteem encompasses beliefs about oneself (for example, "I am loved", "I am worthy") as well as emotional states, such as triumph, despair, pride, and shame. Smith and Macki ...
and transgenerational trauma have been associated with substance use disorders among Native American teens in the U.S. and Canada. Native American populations exhibit genetic differences in the alcohol-metabolizing enzymes
alcohol dehydrogenase Alcohol dehydrogenases (ADH) () are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to N ...
and
ALDH Aldehyde dehydrogenases () are a group of enzymes that catalyse the oxidation of aldehydes. They convert aldehydes (R–C(=O)) to carboxylic acids (R–C(=O)). The oxygen comes from a water molecule. To date, nineteen ALDH genes have ...
, although evidence that these genetic factors are more prevalent in Native Americans than other ethnic groups has been a subject of debate. According to one 2013 review of academic literature on the issue, there is a "substantial genetic component in Native Americans" and that "most Native Americans lack protective variants seen in other populations." Many scientists have provided evidence of the genetic component of alcohol use disorder by the
biopsychosocial model Biopsychosocial models (BPSM) are a class of trans-disciplinary models which look at the interconnection between biology, psychology, and socio- environmental factors. These models specifically examine how these aspects play a role in a range o ...
of alcohol use disorder.
Molecular genetics Molecular genetics is a branch of biology that addresses how differences in the structures or expression of DNA molecules manifests as variation among organisms. Molecular genetics often applies an "investigative approach" to determine the st ...
research currently has not found one specific gene that is responsible for the rates of alcohol use disorder among Native Americans, implying the phenomenon may be due to an interplay of multiple genes and environmental factors. Research on alcohol use disorder in families suggests that learned behavior augments genetic factors in increasing the probability that children of people with alcohol use disorder will themselves have problems with alcohol misuse.


Genetics and amount of consumption

Having a particular genetic variant (A-allele of ADH1B rs1229984) is associated with non-drinking and lower alcohol consumption. This variant is also associated with favorable cardiovascular profile and a reduced risk of coronary artery disease compared to those without the genetic variant, but it is unknown whether this may be caused by differences in alcohol consumption or by additional
confounding In causal inference, a confounder is a variable that influences both the dependent variable and independent variable, causing a spurious association. Confounding is a causal concept, and as such, cannot be described in terms of correlatio ...
effects of the genetic variant itself.


Gender differences

Historically, according to the ''
British Medical Journal ''The BMJ'' is a fortnightly peer-reviewed medical journal, published by BMJ Publishing Group Ltd, which in turn is wholly-owned by the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world ...
'', "men have been far more likely than women to drink alcohol and to drink it in quantities that damage their health, with some figures suggesting up to a 12-fold difference between the sexes." However, analysis of data collected over a century from multiple countries suggests that the gender gap in
alcohol consumption Drinks containing alcohol (drug), alcohol are typically divided into three classes—beers, wines, and Distilled beverage, spirits—with alcohol content typically between 3% and 50%. Drinks with less than 0.5% are sometimes considered Non-al ...
is narrowing, and that young women (born after 1981) are consuming alcohol more than their male counterparts. Such findings have implications for the way in which alcohol-use prevention and intervention programs are designed and implemented.


Alcohol use disorder

Alcohol use disorder (AUD) is defined as a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. Excessive alcohol use can lead to health-related illness and continuous alcohol engagement can ultimately lead to death. Behavioral factors of AUD include binge drinking and heavy alcohol use throughout one's day. AUD affects each culture differently, but African Americans are found to be the hardest impacted. Common health-related illnesses that stem from AUD but are prevalent in African American communities are liver disease, cirrhosis, hypertension, heart disease, oral cancer, stroke, and more. In 2020, heart disease ranked number 3 in the leading cause of death for African Americans ages 15–24. However, on the, contrary African Americans have been proven to consume less alcohol than other counterparts. According to American's Health Rankings, 15.4% of blacks reported excessive drinking, 19.4% of Hispanics, 19.2% of whites and 16.9% of Native Americans. In the United States, social economic status affects, one's ability to access basic necessities to support one's health, life, and survival. If one has a higher socioeconomic status, their income is higher, they are able to support their living needs and have better access to healthcare. Higher SES status reduces the risk of AUD for all individuals. However, those with a lower socioeconomic status majority of minorities are less fortunate. They are faced with poverty, low income, unemployment, and lack of access to healthier food options, which then contributes to poor health and higher AUD risk. The correlation between levels of socioeconomic status is prominent in alcohol-related health illnesses between cultures.


Sensitivity

Several biological factors make women more vulnerable to the effects of alcohol than men. * Body fat. Women tend to weigh less than men, and—pound for pound—a woman's body contains less water and more fatty tissue than a man's. Because fat retains alcohol while water dilutes it, alcohol remains at higher concentrations for longer periods of time in a woman's body, exposing her brain and other organs to more alcohol. * Enzymes. Women have lower levels of two enzymes—alcohol dehydrogenase and aldehyde dehydrogenase—that metabolize (break down) alcohol in the stomach and liver. As a result, women absorb more alcohol into their bloodstreams than men. * Hormones. Changes in hormone levels during the menstrual cycle may also affect how a woman metabolizes alcohol.


Metabolism

Females demonstrated a higher average rate of elimination (mean, 0.017; range, 0.014–0.021 g/210 L) than males (mean, 0.015; range, 0.013–0.017 g/210 L). Female subjects on average had a higher percentage of body fat (mean, 26.0; range, 16.7–36.8%) than males (mean, 18.0; range, 10.2–25.3%). Further explanation for the difference in alcohol metabolism between males and females can be found in higher
alcohol dehydrogenase Alcohol dehydrogenases (ADH) () are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to N ...
activity in female livers.


Depression

The link between alcohol consumption, depression, and gender was examined by the Centre for Addiction and Mental Health (Canada). The study found that women taking
antidepressant Antidepressants are a class of medications used to treat major depressive disorder, anxiety disorders, chronic pain, and addiction. Common side effects of antidepressants include Xerostomia, dry mouth, weight gain, dizziness, headaches, akathi ...
s consumed more alcohol than women who did not experience depression as well as men taking antidepressants. The researchers, Kathryn Graham and a PhD Student, Agnes Massak, analyzed the responses to a survey by 14,063 Canadian residents aged 18–76 years. The survey included measures of quantity, frequency of drinking, depression, and antidepressant use, over the period of a year. The researchers used data from the GENACIS Canada survey, part of an international collaboration to investigate the influence of cultural variation on gender differences in alcohol use and related problems. The purpose of the study was to examine whether, like in other studies already conducted on male depression and alcohol consumption, depressed women also consumed less alcohol when taking anti-depressants. According to the study, both men and women experiencing depression (but not on antidepressants) drank more than non-depressed counterparts. Men taking antidepressants consumed significantly less alcohol than depressed men who did not use antidepressants. Non-depressed men consumed 436 drinks per year, compared to 579 drinks for depressed men not using antidepressants, and 414 drinks for depressed men who used antidepressants. Alcohol consumption remained higher whether the depressed women were taking antidepressants or not. 179 drinks per year for non-depressed women, 235 drinks for depressed women not using antidepressants, and 264 drinks for depressed women who used antidepressants. The lead researcher argued that the study "suggests that the use of antidepressants is associated with lower alcohol consumption among men with depression. But this does not appear to be true for women."


Teenage alcohol abuse

While most teens understand the negative impacts of drinking a lot of alcohol in one sitting, many believe that consuming some alcohol will not be that risky of a behavior. However, teens who drink alcohol on average consume more alcohol in one sitting than most adults, and nearly half of all teens who consumed some amount of alcohol in the past 30 days had done so in excess. Not only are teen drinkers more likely to get drunk, but the effects of drunkenness are worse. The temporarily impaired judgment can lead to permanent consequences such as serious and crippling injury to oneself or others, unplanned pregnancy, or alcoholism later in life. Even if they were to avoid terrible events, they will still suffer irreversible damage to brain development and be far more likely to abuse other substances in the future.


See also

*
Dry January The Dry January challenge is a campaign developed and delivered by UK charity Alcohol Change UK where people sign up to Teetotalism, abstain from alcohol for the month of January. The term "Dry January" is a Trademark, registered trademark with A ...
* Health benefits of quitting alcohol *
Long-term effects of alcohol consumption The long-term effects of alcohol consumption on health are predominantly detrimental, with the severity and range of harms generally increasing with the cumulative amount of alcohol consumed over a lifetime. The extent of these effects varies depen ...
* Short-term effects of alcohol consumption


References


External links


Massive Study Finds Alcohol Is a Leading Contributor to Death And Disease Worldwide
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