HU-345 (cannabinol
quinone
The quinones are a class of organic compounds that are formally "derived from aromatic compounds benzene.html" ;"title="uch as benzene">uch as benzene or naphthalene] by conversion of an even number of –CH= groups into –C(=O)– groups with ...
) is a drug that is able to
angiogenesis inhibitor, inhibit aortic ring angiogenesis
Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and ...
more potently than its parent compound
cannabinol
Cannabinol (CBN) is a mildly psychoactive phytocannabinoid that acts as a low affinity partial agonist at both CB1 and CB2 receptors. This activity at CB1 and CB2 receptors constitutes interaction of CBN with the endocannabinoid system (ECS) ...
(CBN).
It exhibits no psychoactive effects on the body.
HU-345 can be derived through the oxidative degradation of CBN.
See also
*
HU-331
HU-331 is a quinone anticarcinogenic drug synthesized from cannabidiol, a cannabinoid in the ''Cannabis sativa'' plant. It showed a great efficacy against oncogenic human cells. HU-331 does not cause arrest in cell cycle, cell apoptosis or casp ...
*
HU-336
References
{{cannabinoid-stub
Angiogenesis inhibitors
HU cannabinoids
Benzochromenes