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A genetic predisposition is a genetic characteristic which influences the possible
phenotypic In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...
development of an individual organism within a species or population under the influence of
environmental A biophysical environment is a biotic and abiotic surrounding of an organism or population, and consequently includes the factors that have an influence in their survival, development, and evolution. A biophysical environment can vary in scale f ...
conditions. In medicine,
genetic susceptibility Public health genomics is the use of genomics information to benefit public health. This is visualized as more effective preventive care and disease treatments with better Specificity (statistics), specificity, tailored to the genetic makeup of ea ...
to a
disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
refers to a genetic predisposition to a health problem, which may eventually be triggered by particular environmental or lifestyle factors, such as
tobacco smoking Tobacco smoking is the practice of burning tobacco and ingesting the resulting smoke. The smoke may be inhaled, as is done with cigarettes, or simply released from the mouth, as is generally done with pipes and cigars. The practice is believed ...
or
diet Diet may refer to: Food * Diet (nutrition), the sum of the food consumed by an organism or group * Dieting, the deliberate selection of food to control body weight or nutrient intake ** Diet food, foods that aid in creating a diet for weight loss ...
.
Genetic test Genetic testing, also known as DNA testing, is used to identify changes in DNA sequence or chromosome structure. Genetic testing can also include measuring the results of genetic changes, such as RNA analysis as an output of gene expression, o ...
ing is able to identify individuals who are genetically predisposed to certain diseases.


Behavior

Predisposition is the capacity humans are born with to learn things such as language and concept of self. Negative environmental influences may block the predisposition (ability) one has to do some things.
Behaviors Behavior (American English) or behaviour (British English) is the range of actions and mannerisms made by individuals, organisms, systems or artificial entities in some environment. These systems can include other systems or organisms as wel ...
displayed by animals can be influenced by genetic predispositions. Genetic predisposition towards certain human behaviors is scientifically investigated by attempts to identify patterns of human behavior that seem to be invariant over long periods of time and in very different cultures. For example, philosopher
Daniel Dennett Daniel Clement Dennett III (born March 28, 1942) is an American philosopher, writer, and cognitive scientist whose research centers on the philosophy of mind, philosophy of science, and philosophy of biology, particularly as those fields relat ...
has proposed that humans are genetically predisposed to have a
theory of mind In psychology, theory of mind refers to the capacity to understand other people by ascribing mental states to them (that is, surmising what is happening in their mind). This includes the knowledge that others' mental states may be different fro ...
because there has been
evolution Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
ary selection for the human ability to adopt the
intentional stance The intentional stance is a term coined by philosopher Daniel Dennett for the level of abstraction in which we view the behavior of an entity in terms of mental properties. It is part of a theory of mental content proposed by Dennett, which provide ...
. The ''intentional stance'' is a useful behavioral strategy by which humans assume that others have
mind The mind is the set of faculties responsible for all mental phenomena. Often the term is also identified with the phenomena themselves. These faculties include thought, imagination, memory, will, and sensation. They are responsible for various m ...
s like their own. This assumption allows one to predict the behavior of others based on personal knowledge. In 1951,
Hans Eysenck Hans Jürgen Eysenck (; 4 March 1916 – 4 September 1997) was a German-born British psychologist who spent his professional career in Great Britain. He is best remembered for his work on intelligence and personality, although he worked on other ...
and
Donald Prell Donald B. Prell (July 7, 1924 – July 28, 2020) was an American World War II veteran, venture capitalist and futurist who created ''Datamation'', the first magazine devoted solely to the computer hardware and software industry. Early life Prell ...
published an experiment in which identical (monozygotic) and fraternal (dizygotic) twins, ages 11 and 12, were tested for neuroticism. It is described in detail in an article published in the ''
Journal of Mental Science A journal, from the Old French ''journal'' (meaning "daily"), may refer to: *Bullet journal, a method of personal organization *Diary, a record of what happened over the course of a day or other period *Daybook, also known as a general journal, a ...
''. in which Eysenck and Prell concluded that, "The factor of neuroticism is not a statistical artifact, but constitutes a biological unit which is inherited as a whole....neurotic Genetic predisposition is to a large extent hereditarily determined." E. O. Wilson's book on sociobiology and his book
Consilience In science and history, consilience (also convergence of evidence or concordance of evidence) is the principle that evidence from independent, unrelated sources can "converge" on strong conclusions. That is, when multiple sources of evidence are ...
discuss the idea of genetic predisposition of behaviors. The field of
evolutionary psychology Evolutionary psychology is a theoretical approach in psychology that examines cognition and behavior from a modern evolutionary perspective. It seeks to identify human psychological adaptations with regards to the ancestral problems they evolv ...
explores the idea that certain behaviors have been selected for during the course of evolution.


Genetic discrimination in health insurance in US

In US, the
Genetic Information Nondiscrimination Act The Genetic Information Nondiscrimination Act of 2008 (, GINA ), is an Act of Congress in the United States designed to prohibit some types of genetic discrimination. The act bars the use of genetic information in health insurance and employment ...
, which was signed into law by President Bush on May 21, 2008, prohibits discrimination in employment and health insurance based on genetic information.


See also

*
Human nature Human nature is a concept that denotes the fundamental dispositions and characteristics—including ways of thinking, feeling, and acting—that humans are said to have naturally. The term is often used to denote the essence of humankind, or ...
*
Nature versus nurture Nature versus nurture is a long-standing debate in biology and society about the balance between two competing factors which determine fate: genetics (nature) and environment (nurture). The alliterative expression "nature and nurture" in English h ...
*
Behavioral genetics Behavioural genetics, also referred to as behaviour genetics, is a field of scientific research that uses genetic methods to investigate the nature and origins of individual differences in behaviour. While the name "behavioural genetics" c ...
*
Predispositioning Theory Predispositioning theory, in the field of decision theory and systems theory, is a theory focusing on the stages between a complete order and a complete disorder. Predispositioning theory was founded by Aron Katsenelinboigen (1927–2005), a profe ...
*
Psychiatric genetics Psychiatric genetics is a subfield of behavioral neurogenetics and behavioral genetics which studies the role of genetics in the development of mental disorders (such as alcoholism, schizophrenia, bipolar disorder, and autism). The basic principle ...
* Gene-environment correlation *
Eugenics Eugenics ( ; ) is a fringe set of beliefs and practices that aim to improve the genetic quality of a human population. Historically, eugenicists have attempted to alter human gene pools by excluding people and groups judged to be inferior or ...
*
Eggshell skull The eggshell rule (also thin skull rule, papier-mâché-plaintiff rule, or talem qualem rule) is a well-established legal doctrine in common law, used in some tort law systems, with a similar doctrine applicable to criminal law. The rule stat ...
* MODY *
Allergy Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
*
Oncogene An oncogene is a gene that has the potential to cause cancer. In tumor cells, these genes are often mutated, or expressed at high levels.
*
Quantitative trait locus A quantitative trait locus (QTL) is a locus (section of DNA) that correlates with variation of a quantitative trait in the phenotype of a population of organisms. QTLs are mapped by identifying which molecular markers (such as SNPs or AFLPs) c ...
*
Genetic privacy Genetic privacy involves the concept of personal privacy concerning the storing, repurposing, provision to third parties, and displaying of information pertaining to one's genetic information. This concept also encompasses privacy regarding the abi ...


References

# The results of this survey ar
discussed here
(January 20, 1998). #
summary
of U.S.A. executive orders and proposed legislation is compiled by the National Center for Genome Resources. # ''The Intentional Stance'' (MIT Press; Reprint edition 1989) ()


External links


Genetic discrimination fact sheet from the National Human Genome Research Institute
{{DEFAULTSORT:Genetic Predisposition Genetics Behavioural sciences