Gábor Fodor (chemist)
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Gábor Béla Fodor (December 5, 1915 – November 3, 2000) was a Hungarian-American
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of ...
, medical research scientist, and professor of chemistry. His work in academia, which spanned six decades in Europe and later in North America, specialized in research of
antidote An antidote is a substance that can counteract a form of poisoning. The term ultimately derives from the Greek term φάρμακον ἀντίδοτον ''(pharmakon antidoton)'', "(medicine) given as a remedy". An older term in English which is ...
s,
painkiller An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in s ...
s,
tropane alkaloids Tropane alkaloids are a class of bicyclic .2.1alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloi ...
, and derivatives of
vitamin C Vitamin C (also known as ascorbic acid and ascorbate) is a water-soluble vitamin found in citrus and other fruits, berries and vegetables. It is also a generic prescription medication and in some countries is sold as a non-prescription di ...
. His research helped in finding treatments for
cancer Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Po ...
,
stroke Stroke is a medical condition in which poor cerebral circulation, blood flow to a part of the brain causes cell death. There are two main types of stroke: brain ischemia, ischemic, due to lack of blood flow, and intracranial hemorrhage, hemor ...
s,
Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease and the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As the disease advances, symptoms can include problems wit ...
, and other illnesses.


Early life

Gábor Fodor was born in Budapest. His father was Domokos Fodor, an ethnic Hungarian born in
Transylvania Transylvania ( or ; ; or ; Transylvanian Saxon dialect, Transylvanian Saxon: ''Siweberjen'') is a List of historical regions of Central Europe, historical and cultural region in Central Europe, encompassing central Romania. To the east and ...
,
Romania Romania is a country located at the crossroads of Central Europe, Central, Eastern Europe, Eastern and Southeast Europe. It borders Ukraine to the north and east, Hungary to the west, Serbia to the southwest, Bulgaria to the south, Moldova to ...
. His mother was Paola Maria Bayer, a Roman Catholic of Jewish ancestry from Budapest. Gábor Fodor attended the
University of Szeged The University of Szeged () is a Public university, public research university in Szeged, Hungary. Established as the Jesuit Academy of Kolozsvár in present-day Cluj-Napoca in 1581, the institution was re-established as a university in 1872 by ...
, and he earned his Ph.D. magna cum laude. He isolated
scopolamine Scopolamine, also known as hyoscine, or Devil's Breath, is a medication used to treat motion sickness and postoperative nausea and vomiting. It is also sometimes used before surgery to decrease saliva. When used by injection, effects begin a ...
, during his years working at the University of Szeged. He was awarded the highest recognition of Hungary, the
Kossuth Prize The Kossuth Prize (, ) is a state-sponsored award in Hungary, named after the Hungarian politician and revolutionist Lajos Kossuth. The Prize was established in 1936, by the Hungarian National Assembly, to acknowledge outstanding personal and grou ...
in 1950. He later worked at Budapest's Chinoin Laboratories. Scopolamine was a highly important compound during World War II. Fodor succeeded twice in escaping imprisonment, and possible internment at a concentration camp due to his Jewish ancestry, during Nazi Germany's control of
Hungary Hungary is a landlocked country in Central Europe. Spanning much of the Pannonian Basin, Carpathian Basin, it is bordered by Slovakia to the north, Ukraine to the northeast, Romania to the east and southeast, Serbia to the south, Croatia and ...
. He became part of the faculty of chemistry of the
University of Szeged The University of Szeged () is a Public university, public research university in Szeged, Hungary. Established as the Jesuit Academy of Kolozsvár in present-day Cluj-Napoca in 1581, the institution was re-established as a university in 1872 by ...
after
World War II World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the wo ...
. He remained there as Provost until 1957, when he was forced to flee the country due to his participation in faculty and student rebellions during the
Hungarian Revolution of 1956 The Hungarian Revolution of 1956 (23 October – 4 November 1956; ), also known as the Hungarian Uprising, was an attempted countrywide revolution against the government of the Hungarian People's Republic (1949–1989) and the policies caused by ...
against the Soviet domination of Hungary.


Career

He received asylum in
London London is the Capital city, capital and List of urban areas in the United Kingdom, largest city of both England and the United Kingdom, with a population of in . London metropolitan area, Its wider metropolitan area is the largest in Wester ...
and then in
Canada Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of coun ...
. In 1964, he joined
Laval University Laval means ''The Valley'' in old French and is the name of: People * House of Laval, a French noble family originating from the town of Laval, Mayenne * Laval (surname) Places Belgium * Laval, a village in the municipality of Sainte-Ode, Luxe ...
in
Canada Canada is a country in North America. Its Provinces and territories of Canada, ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, making it the world's List of coun ...
, where he taught until 1968. In 1969 he moved to the
United States The United States of America (USA), also known as the United States (U.S.) or America, is a country primarily located in North America. It is a federal republic of 50 U.S. state, states and a federal capital district, Washington, D.C. The 48 ...
to accept a faculty position in the Department of Chemistry at
West Virginia University West Virginia University (WVU) is a public university, public Land-grant university, land-grant research university with its main campus in Morgantown, West Virginia, United States. Its other campuses are those of the West Virginia University Ins ...
. He taught for the rest of his life at West Virginia University Professor, first as Professor of Chemistry, then as a Centennial Professor of Chemistry (1969–1986); finally, as Professor
Emeritus ''Emeritus/Emerita'' () is an honorary title granted to someone who retires from a position of distinction, most commonly an academic faculty position, but is allowed to continue using the previous title, as in "professor emeritus". In some c ...
until his death on November 3, 2000. He was an active member of the university community, and one of the founders of West Virginia University's annual Benedum Lecture Series. In the year after his death, the next Benedum Lectures Series were held in his memory. Fodor's specialized field of research concentrated on
tropane alkaloids Tropane alkaloids are a class of bicyclic .2.1alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Certain tropane alkaloi ...
. Fodor conducted early studies of powerful drugs of this group found in natural sources. Such studies included an early configuration of cocaine, as well as early studies of its medicinal uses. Numerous studies of other compounds followed. He worked with friend and fellow countryman,
Albert Szent-Györgyi Albert Imre Szent-Györgyi de Rapoltu Mare, Nagyrápolt (; September 16, 1893 – October 22, 1986) was a Hungarian biochemist who won the Nobel Prize in Physiology or Medicine in 1937. He is credited with first isolating vitamin C and disc ...
(
Nobel Prize in Medicine The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute, Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single ...
1937), under whose direction he isolated new vitamins and derivatives. Their work connection and friendship had a profound effect on the rest of Fodor's work, especially on his successive work with Vitamin C derivatives. In the last decades of his life, he remained active in collaborations with American pharmaceutical laboratory research, scientific publications, and continued to work as a retired professor in the West Virginia University Department of Chemistry. He wrote for scientific journals in Canada and the United States. Fodor was diagnosed with third-stage lung cancer in late 1999, and he moved to
San Diego San Diego ( , ) is a city on the Pacific coast of Southern California, adjacent to the Mexico–United States border. With a population of over 1.4 million, it is the List of United States cities by population, eighth-most populous city in t ...
,
California California () is a U.S. state, state in the Western United States that lies on the West Coast of the United States, Pacific Coast. It borders Oregon to the north, Nevada and Arizona to the east, and shares Mexico–United States border, an ...
, for specialized treatment. He died on November 3, 2000. Posthumously, the
Hungarian Academy of Sciences The Hungarian Academy of Sciences ( , MTA) is Hungary’s foremost and most prestigious learned society. Its headquarters are located along the banks of the Danube in Budapest, between Széchenyi rakpart and Akadémia utca. The Academy's primar ...
published his memoirs: ''Egy magyar kémikus élete.''Library index


References

{{DEFAULTSORT:Fodor, Gabor 1915 births 2000 deaths University of Szeged alumni West Virginia University faculty 20th-century Hungarian chemists Hungarian scientists American medical researchers Hungarian emigrants to the United States