Garre's Sclerosing Osteomyelitis
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Garre's sclerosing osteomyelitis is a type of chronic
osteomyelitis Osteomyelitis (OM) is the infectious inflammation of bone marrow. Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. The feet, spine, and hips are the most commonly involved bones in adults. The cause is ...
also called periostitis ossificans and Garré's sclerosing osteomyelitis. It is a
rare disease A rare disease is any disease that affects a small percentage of the population. In some parts of the world, the term orphan disease describes a rare disease whose rarity results in little or no funding or research for treatments, without financi ...
. It mainly affects children and young adults. It is associated with a low grade infection, which may be due to
dental caries Tooth decay, also known as caries,The word 'caries' is a mass noun, and is not a plural of 'carie'.'' is the breakdown of teeth due to acids produced by bacteria. The resulting cavities may be a number of different colors, from yellow to black ...
(cavities in the teeth). The body of the
mandible In jawed vertebrates, the mandible (from the Latin ''mandibula'', 'for chewing'), lower jaw, or jawbone is a bone that makes up the lowerand typically more mobilecomponent of the mouth (the upper jaw being known as the maxilla). The jawbone i ...
may show irregular lucent/opaque changes with subperiosteal opaque layering along inferior border. It is a chronic osteomyelitis with subperiosteal bone and
collagen Collagen () is the main structural protein in the extracellular matrix of the connective tissues of many animals. It is the most abundant protein in mammals, making up 25% to 35% of protein content. Amino acids are bound together to form a trip ...
deposition. There is no suppuration and sinus formation. It was first described by the Swiss surgeon Carl Garré and is named after him.


References

Bacterial diseases Skeletal disorders Osteopathies Rare diseases Jaw disorders Rare infectious diseases {{musculoskeletal-disease-stub