The frontal sinuses are one of the four pairs of
paranasal sinuses
Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphe ...
that are situated behind the
brow ridges.
Sinuses
Paranasal sinuses are a group of four paired air-filled spaces that surround the nasal cavity. The maxillary sinuses are located under the eyes; the frontal sinuses are above the eyes; the ethmoidal sinuses are between the eyes and the sphenoi ...
are
mucosa
A mucous membrane or mucosa is a membrane that lines various cavities in the body of an organism and covers the surface of internal organs. It consists of one or more layers of epithelial cells overlying a layer of loose connective tissue. It ...
-lined airspaces within the bones of the face and skull. Each opens into the anterior part of the corresponding
middle nasal meatus
In anatomy, the term nasal meatus can refer to any of the three meatuses (passages) through the skulls nasal cavity: the superior meatus (''meatus nasi superior''), middle meatus (''meatus nasi medius''), and inferior meatus (''meatus nasi infer ...
of the nose through the
frontonasal duct which traverses the anterior part of the labyrinth of the
ethmoid
The ethmoid bone (; from ) is an unpaired bone in the skull that separates the nasal cavity from the brain. It is located at the roof of the nose, between the two orbit (anatomy), orbits. The cubical (cube-shaped) bone is lightweight due to a sp ...
. These structures then open into the
semilunar hiatus in the
middle meatus.
Structure

Each frontal sinus is situated between the external and internal plates of the frontal bone.
Their average measurements are as follows: height 28 mm, breadth 24 mm, depth 20 mm, creating a space of 6-7 ml.
[University of Texas Medical Branch](_blank)
/ref>
Each frontal sinus extends into the squamous part of the frontal bone superiorly, and into the orbital part of frontal bone posteriorly to come to occupy the medial part of the roof of the orbit.
Each sinus drains through an opening in its inferomedial part into the frontonasal duct.
Vasculature
The mucous membrane of the frontal sinus receives arterial supply from the supraorbital artery
The supraorbital artery is a branch of the ophthalmic artery. It passes anteriorly within the orbit to exit the orbit through the supraorbital foramen or notch alongside the supraorbital nerve, splitting into two terminal branches which go on to f ...
, and anterior ethmoidal artery.
Venous drainage is provided by the superior ophthalmic vein.
Lymph is drained into the submandibular lymph nodes.
Innervation
The mucous membrane of the sinus is innervated by the supraorbital nerve
The supraorbital nerve is one of two terminal branches - the other being the supratrochlear nerve - of the frontal nerve (itself a branch of the ophthalmic nerve (CN V1)). It exits the orbit via the supraorbital foramen/notch before splitting ...
, which contains the postganglionic
In the autonomic nervous system, nerve fibers from the ganglion to the wikt:effector, effector organ are called postganglionic nerve fibers.
Neurotransmitters
The neurotransmitters of postganglionic fibers differ:
* In the parasympathetic div ...
parasympathetic
The parasympathetic nervous system (PSNS) is one of the three divisions of the autonomic nervous system, the others being the sympathetic nervous system and the enteric nervous system.
The autonomic nervous system is responsible for regulat ...
nerve fibers for mucous secretion
Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mec ...
from the ophthalmic nerve
The ophthalmic nerve (CN V1) is a sensory nerve of the head. It is one of three divisions of the trigeminal nerve (CN V), a cranial nerve. It has three major branches which provide sensory innervation to the eye, and the skin of the upper face ...
.
Anatomical variation
Frontal sinuses are rarely symmetrical as the septum
In biology, a septum (Latin language, Latin for ''something that encloses''; septa) is a wall, dividing a Body cavity, cavity or structure into smaller ones. A cavity or structure divided in this way may be referred to as septate.
Examples
Hum ...
between them frequently deviates to either side of the midline. The two sinuses also vary in extent compared to one another.
Their size of the frontal sinuses is highly variable. Rarely, one or both sinuses is hypoplastic or even absent.
Sexual dimorphism
Prominence of frontal sinuses is sexual dimorphic; they are more prominent in males, whereas less so in children and in females, resulting in an oblique forehead in males that is a male sexual characteristic.
Development
The frontal sinuses are the only sinuses that are absent at birth. They begin to appear during the second year of life as excavations in the diploë
Diploë ( or ) is the spongy cancellous bone separating the inner and outer layers of the cortical bone of the skull. It is a subclass of trabecular bone.
In the cranial bones, the layers of compact cortical tissue are familiarly known as the ...
. The development of these sinuses accounts for the suddenly increased mucus production at this age. They are generally well developed, and functional between the sixth and eighth years, though they continue to grow slower until reaching their maximum size after puberty
Puberty is the process of physical changes through which a child's body matures into an adult body capable of sexual reproduction. It is initiated by hormonal signals from the brain to the gonads: the ovaries in a female, the testicles i ...
.[Human Anatomy, Jacobs, Elsevier, 2008, page 210]
Function
Through its copious mucus production, the sinus is an essential part of the immune defense/air filtration carried out by the nose. Nasal and sinal mucosae are ciliated and move mucus to the choanae and finally to the stomach. The thick upper layers of nasal mucus trap bacteria and small particles in tissue abundantly provided with immune cells
White blood cells (scientific name leukocytes), also called immune cells or immunocytes, are cells of the immune system that are involved in protecting the body against both infectious disease and foreign entities. White blood cells are genera ...
, antibodies
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that caus ...
, and antibacterial proteins. The layers beneath are thinner and provide a substrate in which the cilia are able to beat and move the upper layer with its debris through the ostia toward the choanae.
Clinical significance
Infection of the frontal sinus causing sinusitis can give rise to serious complications, as it is in close proximity to the orbit and cranial cavity ( orbital cellulitis, epidural
Epidural administration (from Ancient Greek ἐπί, "upon" + '' dura mater'') is a method of medication administration in which a medicine is injected into the epidural space around the spinal cord. The epidural route is used by physicians ...
and subdural abscess, meningitis
Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, intense headache, vomiting and neck stiffness and occasion ...
).
Endonasal approach into the frontal sinus in children with acute and chronic frontal sinusitis without the usage of surgical optics is not successful, because in this case the operation is performed almost blindly and technically difficult even in adults.
Fractures
Frontal sinus fractures occur from trauma to the part of the frontal bone that overlies the sinus, often from motor vehicle accidents and falls. The hallmarks of a frontal sinus fracture is a frontal depression in the anterior table of the bone. Additionally, clear fluid leaking from the nose may indicate that fractures to the posterior table have torn into the dura mater, creating a cerebrospinal fluid
Cerebrospinal fluid (CSF) is a clear, colorless Extracellular fluid#Transcellular fluid, transcellular body fluid found within the meninges, meningeal tissue that surrounds the vertebrate brain and spinal cord, and in the ventricular system, ven ...
leak.
Goals in management are to protect the intracranial structure, control any existing CSF leakage, prevent late complications, and aesthetically correct the deformity caused, if any. In anterior table fractures, if the table is minimally displaced, there will be no treatment necessary, only observation. If largely displaced, the correction is open reduction and internal fixation. If inhibiting the nasofrontal outflow tract, procedure is to undergo open reduction and internal fixation of the anterior table and osteoplastic flap with obliteration.
In posterior table fractures, a nondiplaced fracture with no CSF leak will only be observed. Those with a CSF leak will undergo sinus exploration if the CSF leak is not internally resolved within 4 to 7 days. With more dramatic displacements, sinus exploration will be required to determine the required level of cranialization, obliteration, and reparation to the dura.
Aesthetic reconstruction
In the case of facial feminization surgery, modifications to the frontal sinus can be made to make the face more feminine, alongside softening the orbital rims. The forehead operations for feminization were first described by Dr. Douglas Ousterhout in the 1980s. Those operations consisted of four different techniques based on the anatomy of the patient. They were named arbitrarily by number (Type 1, Type 2, Type 3 and Type 4), with no particular relevance to their level of difficulty or frequency.
* Type 1
The Type I forehead describes a forehead with an absent frontal sinus or alternatively with sufficiently thick bone overlaying the frontal sinus so that burring alone is enough to correct the forehead. This type of forehead tends to occur in approximately 3% to 5% of the population. In these situations, the operation consists of using rotary instruments to shape and contour the bone to the desired level, while observing the thickness of the bone to avoid penetrating the intracranial space. The main risks associated with this operation tend to be bleeding. There are often venous lakes present throughout the frontal bone.
* Type 2
The Type II forehead describes another uncommon situation. This describes a patient with brow bossing; however, the bossing is at the correction position in terms of prominence. Therefore, the problem lies primarily above the bossing. We see this forehead type at about the same frequency as we see the Type I forehead. The Type II forehead is corrected by using a filling material such as methyl methacrylate.7 Other materials may be more ideal at this point; however, none are superior in terms of cost to methyl methacrylate. Although many surgeons do not consider the cost of the materials they are using, hydroxyapatite and calcium phos-phate bone cements cost approximately 1000 times that of methyl methacrylate. The advantage of bone cement is its adherence to the underlying bone, and the more analogous nature to native bone substrate. The material is applied to fill in the area above the bossing, and then gently contoured to blend with the transverse forehead bossing thereby-creating a uniformly round forehead
* Type 3
The Type III forehead is the most common situation and occurs in more than 90% of patients. The forehead, in this situation, has a prominent bossing across the top of the brows, and that bossing is overly projected. A frontal sinus is present. The thinness of the sinus precludes using exclusively rotary instruments to thin the bone. An osteotomy and reconstruction are the only operations to provide the proper round shape to the forehead with the decreased prominence that is necessary for a soft forehead, which involves a setback of the anterior table of the frontal sinus. This procedure is described as Type 3 Forehead Cranioplasty.
* Type 4
This operation can be described as an extended Type II operation. In this situation, the entire forehead is diminutive, including the area underlying the brows, and the entire forehead requires augmentation. Regardless of the material type, care should be taken to avoid having the implant sit directly underneath the incision as this leads to a higher rate of infection and removal.
Treatment of the orbital rim is almost always necessary in all these various forehead operations, regardless of what is done with the frontal bossing.[Deschamps-Braly JC. Approach to Feminization Surgery and Facial Masculinization Surgery: Aesthetic Goals and Principles of Management. ''J Craniofac Surg''. 2019;30(5):1352‐1358. doi:10.1097/SCS.0000000000005391]
References
External links
*
* (, )
Use of Frontal Sinus Transillumination For Cranioplasty in Facial Feminization Surgery
Approach to Feminization Surgery and Facial Masculinization Surgery: Aesthetic Goals and Principles of Management.
{{Authority control
Bones of the head and neck
Otorhinolaryngology
Rhinology
Sinus surgery