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Charles Ernest Overton (1865–1933) was a British physiologist and biologist, now regarded as a pioneer of the theory of the
cell membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment ( ...
. In the last years of the 19th century Overton did experimental work, allowing the distinction to be drawn between the
cell wall A cell wall is a structural layer surrounding some types of cells, just outside the cell membrane. It can be tough, flexible, and sometimes rigid. It provides the cell with both structural support and protection, and also acts as a filtering mech ...
of plants and their
cytoplasmic membrane The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment ( ...
. He studied the permeability of a range of biological materials to around 500 chemical compounds. In 1900, Overton proposed a biomembrane model "Overton Biomembrane Model" which stated that biomembranes are made up of lipids. He gave this statement on the basis of observation of transport of lipid soluble substances across the biomembranes. He came to
Lund University , motto = Ad utrumque , mottoeng = Prepared for both , established = , type = Public research university , budget = SEK 9 billion Louise Petrén-Overton Hedvig Louise Beata Petrén-Overton (August 12, 1880 – January 14, 1977) was a Swedish mathematician, the first woman in Sweden with a doctorate in mathematics. Early life and education Louise Petrén was one of twelve children of the vicar of ...
, the first woman in Sweden with a doctorate in mathematics; they had four children.


See also

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Meyer-Overton hypothesis Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) sti ...


Notes

{{DEFAULTSORT:Overton, Ernest 1865 births 1933 deaths 19th-century British biologists 20th-century British biologists British physiologists Lund University faculty