Charles Ernest Overton (1865–1933) was a British physiologist and biologist, now regarded as a pioneer of the theory of the
cell membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment ( ...
.
In the last years of the 19th century Overton did experimental work, allowing the distinction to be drawn between the
cell wall
A cell wall is a structural layer surrounding some types of cells, just outside the cell membrane. It can be tough, flexible, and sometimes rigid. It provides the cell with both structural support and protection, and also acts as a filtering mech ...
of plants and their
cytoplasmic membrane
The cell membrane (also known as the plasma membrane (PM) or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of all cells from the outside environment ( ...
.
He studied the
permeability of a range of biological materials to around 500 chemical compounds.
In 1900, Overton proposed a biomembrane model "Overton Biomembrane Model" which stated that biomembranes are made up of lipids. He gave this statement on the basis of observation of transport of lipid soluble substances across the biomembranes.
He came to
Lund University
, motto = Ad utrumque
, mottoeng = Prepared for both
, established =
, type = Public research university
, budget = SEK 9 billion [Louise Petrén-Overton
Hedvig Louise Beata Petrén-Overton (August 12, 1880 – January 14, 1977) was a Swedish mathematician, the first woman in Sweden with a doctorate in mathematics.
Early life and education
Louise Petrén was one of twelve children of the vicar of ...]
, the first woman in Sweden with a doctorate in mathematics; they had four children.
See also
*
Meyer-Overton hypothesis Minimum alveolar concentration or MAC is the concentration, often expressed as a percentage by volume, of a vapour in the alveoli of the lungs that is needed to prevent movement (motor response) in 50% of subjects in response to surgical (pain) sti ...
Notes
{{DEFAULTSORT:Overton, Ernest
1865 births
1933 deaths
19th-century British biologists
20th-century British biologists
British physiologists
Lund University faculty