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The human earlobe (''lobulus auriculae''), the lower portion of the outer ear, is composed of tough areolar and
adipose Adipose tissue (also known as body fat or simply fat) is a loose connective tissue composed mostly of adipocytes. It also contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, Blood vessel, vascular endothel ...
connective tissue Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesod ...
s, lacking the firmness and elasticity of the rest of the auricle (the external structure of the ear). In some cases the lower lobe is connected to the side of the face. Since the earlobe does not contain
cartilage Cartilage is a resilient and smooth type of connective tissue. Semi-transparent and non-porous, it is usually covered by a tough and fibrous membrane called perichondrium. In tetrapods, it covers and protects the ends of long bones at the joints ...
it has a large
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
supply and may help to warm the ears. However, earlobes are not generally considered to have any major biological function. The earlobe contains many nerve endings, and for some people is an
erogenous zone An erogenous zone (from Greek , ''érōs'' "love"; and English ''-genous'' "producing", from Greek , ''-genḗs'' "born") is an area of the human body that has heightened Sensory processing, sensitivity, the sexual stimulation, stimulation of wh ...
. The zoologist
Desmond Morris Desmond John Morris FLS ''hon. caus.'' (born 24 January 1928) is an English zoologist, ethologist and surrealist painter, as well as a popular author in human sociobiology. He is known for his 1967 book ''The Naked Ape'', and for his televis ...
in his book ''
The Naked Ape ''The Naked Ape: A Zoologist's Study of the Human Animal'' is a 1967 book by English Zoology, zoologist and ethology, ethologist Desmond Morris that looks at humans as a species and compares them to other animals. ''The Human Zoo (book), The Hum ...
'' (1967) conjectured that the lobes developed as an additional erogenous zone to facilitate the extended sexuality necessary in the evolution of human monogamous pair bonding.


Organogenesis

The earlobe, as a body part built of
epithelium Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of man ...
and
connective tissue Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesod ...
, might appear to be derived from
dermatome Dermatome may refer to: * Dermatome (anatomy), an area of skin that is supplied by a single pair of dorsal roots * Dermatome (embryology), the portion of the embryonic paraxial mesoderm, the somite, which gives rise to dermis * Dermatome (instrument ...
. But this is not the case, as in the surrounding tissue there are no
somite The somites (outdated term: primitive segments) are a set of bilaterally paired blocks of paraxial mesoderm that form in the embryogenesis, embryonic stage of somitogenesis, along the head-to-tail axis in segmentation (biology), segmented animals. ...
s and thus no dermatome. In this area, the
dermis The dermis or corium is a layer of skin between the epidermis (skin), epidermis (with which it makes up the cutis (anatomy), cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from s ...
is derived from cells of mesenchymal cells: the mesenchyme is derived from the
sclerotome The somites (outdated term: primitive segments) are a set of bilaterally paired blocks of paraxial mesoderm that form in the embryogenesis, embryonic stage of somitogenesis, along the head-to-tail axis in segmentation (biology), segmented animals. ...
and splanchnopleura located in the nearby regions of the
torso The torso or trunk is an anatomical terminology, anatomical term for the central part, or the core (anatomy), core, of the body (biology), body of many animals (including human beings), from which the head, neck, limb (anatomy), limbs, tail an ...
. The earlobe as a body part arises and develops in the vicinity of auricular follicle, as a result of cascade induction: # The first-level inductor is the central segment of Archenteron's roof, which induces the production of the
Medulla oblongata The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involun ...
(part of the
Hindbrain The hindbrain, rhombencephalon (shaped like a rhombus) is a developmental categorization of portions of the central nervous system in vertebrates. It includes the medulla, pons, and cerebellum. Together they support vital bodily processes. Met ...
). # The second-level inductor is the
Medulla oblongata The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involun ...
, which induces the production of a pair of auricular follicles derived from the
mesoderm The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical ...
. # The third-level inductor is the auricular follicle, which induces the production of the
auditory bulla The tympanic part of the temporal bone is a curved plate of bone lying below the squamous part of the temporal bone, in front of the mastoid process, and surrounding the external part of the ear canal. It originates as a separate bone (tympanic b ...
.


Genetics

Earlobes average about 2 centimeters long, and elongate slightly with age. Although the "free" vs. "attached" appearance of earlobes is often presented as an example of a simple "one gene – two alleles" Mendelian trait in humans, earlobes do not all fall neatly into either category; there is a continuous range from one extreme to the other, suggesting the influence of several genes.Mader S. S. (2000): Human Biology. McGraw–Hill, New York, .


Clinical issues

Earlobes are normally smooth, but occasionally exhibit creases. Creased earlobes are sometimes associated with genetic disorders in children, including Beckwith-Wiedemann syndrome. In some early studies, earlobe creases were thought to be associated with an increased risk of
heart attack A myocardial infarction (MI), commonly known as a heart attack, occurs when Ischemia, blood flow decreases or stops in one of the coronary arteries of the heart, causing infarction (tissue death) to the heart muscle. The most common symptom ...
and
coronary heart disease Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), is a type of cardiovascular disease, heart disease involving Ischemia, the reduction of blood flow to the cardiac muscle due to a build-up ...
. But more recent studies have concluded that, since earlobes become more creased with age, and older people are more likely to have heart disease than younger people, age rather than intrinsic factors may account for the findings linking heart attack to earlobe creases. The earlobe crease is also called Frank's Sign.


Society and culture


Earlobe piercing and stretching

Piercing the earlobes is a commonplace activity in many cultures in many historical eras; no other location on the body is as commonly pierced. Consequently, injury to the earlobe due to the weight of heavy earrings is also common. Some cultures practice earlobe stretching for decorative effects, using piercing ornaments to stretch and enlarge the earlobes to accommodate plugs.


Negative effects of wearing earrings

Some research has found that the most frequent complications connected with wearing earrings are: *
inflammation Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', '' ...
, *
keloid Keloid, also known as keloid disorder and keloidal scar, is the formation of a type of scar which, depending on its maturity, is composed mainly of either type III (early) or type I (late) collagen. It is a result of an overgrowth of granulation t ...
s, * loss of tissue by tearing, and * mechanical division of earlobes. A noticeable relationship has been found by Polish scientists between the piercing of young girls' earlobes and their subsequently developing allergic skin reactions.Harmful earrings (pl. Szkodliwe kolczyki)
Fizjointormator. Retrieved 2015-04-01

Tvn24. Retrieved 2015-04-01
In the view of Professor Ewa Czarnobilska, the manager of the research team, the primary reason for the allergies connected to earrings is the presence of
nickel Nickel is a chemical element; it has symbol Ni and atomic number 28. It is a silvery-white lustrous metal with a slight golden tinge. Nickel is a hard and ductile transition metal. Pure nickel is chemically reactive, but large pieces are slo ...
, which is a common component of the alloys used in jewelry production and leaches from the earrings. The symptom seen is generally
eczema Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened ...
, and is often misdiagnosed as a
food allergy A food allergy is an abnormal immune system, immune response to food. The symptoms of the allergic reaction may range from mild to severe. They may include pruritus, itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathi ...
, for instance to milk. The specific mechanism in allergies caused by earrings is the contact of nickel ions with the
lymphatic system The lymphatic system, or lymphoid system, is an organ system in vertebrates that is part of the immune system and complementary to the circulatory system. It consists of a large network of lymphatic vessels, lymph nodes, lymphoid organs, lympha ...
. The study noted that children who stopped wearing earrings did not see the disappearance of the allergic symptoms. The
immune system The immune system is a network of biological systems that protects an organism from diseases. It detects and responds to a wide variety of pathogens, from viruses to bacteria, as well as Tumor immunology, cancer cells, Parasitic worm, parasitic ...
remembers the presence of the nickel ions in the person's
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood is com ...
and
lymph Lymph () is the fluid that flows through the lymphatic system, a system composed of lymph vessels (channels) and intervening lymph nodes whose function, like the venous system, is to return fluid from the tissues to be recirculated. At the ori ...
, so the child can still react to: * metal parts of wardrobe, * dental braces, * dental prosthesis, *
orthotics Orthotics () is a medical specialty that focuses on the design and application of orthoses, sometimes known as braces, calipers, or splints. An is "an externally applied device used to influence the structural and functional characteristics of ...
, * meals cooked in pots with addition of nickel, * margarine (nickel is a catalyst in hydrogenation of unsaturated fats), * coins, * chocolate, * nuts, * leguminous vegetables, * wine, and * beer. Research by allergists has found that in a sample of 428 pupils of ages 7–8 and 16–17 years old: * 30% of the research population showed an allergy to nickel, and * the allergy occurred in girls who had started wearing earrings in early childhood.


References


Further reading

* {{Authority control Ear de:Ohrmuschel#Ohrläppchen