DOMINE is a

database In computing, a database is an organized collection of data or a type of data store based on the use of a database management system (DBMS), the software that interacts with end users, applications, and the database itself to capture and a ...

of known and predicted

protein domain In molecular biology, a protein domain is a region of a protein's Peptide, polypeptide chain that is self-stabilizing and that Protein folding, folds independently from the rest. Each domain forms a compact folded Protein tertiary structure, thre ...

interactions (or domain-domain interactions). It contains interactions observed in PDB crystal structures, and those predicted by several computational approaches. DOMINE uses Pfam HMM profiles for

definitions. The DOMINE database contains 26,219 interactions among 5,410 domains), which includes 6,634 known interactions inferred from PDB structure data.

References

See also