David Fenyö is a Hungarian-Swedish-American computational biologist, physicist and businessman. He is currently professor in the Department of Biochemistry and Molecular Pharmacology at

NYU Langone Medical Center NYU Langone Health is an integrated Health system, academic health system located in New York City, New York, United States. The health system consists of the New York University Grossman School of Medicine, NYU Grossman School of Medicine and NY ...

. Fenyö's research focuses on the development of methods to identify, characterize and quantify proteins and in the integration of data from multiple modalities including mass spectrometry, sequencing and microscopy.

Career and research

Fenyö studied engineering physics, with a focus on mathematical and numerical methods, at

Uppsala University Uppsala University (UU) () is a public university, public research university in Uppsala, Sweden. Founded in 1477, it is the List of universities in Sweden, oldest university in Sweden and the Nordic countries still in operation. Initially fou ...

in Sweden. After receiving an M.Sc. in 1987, he joined the laboratory of Bo Sundqvist at Uppsala University, and studied the mechanisms of ion–solid interaction both experimentally, theoretically and using molecular dynamics and

Monte Carlo simulations Monte Carlo methods, or Monte Carlo experiments, are a broad class of computational algorithms that rely on repeated random sampling to obtain numerical results. The underlying concept is to use randomness to solve problems that might be det ...

. He graduated with a Ph.D. in Physics in 1991. He then went on to complete his postdoctoral work at

Rockefeller University The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and pro ...

with Brian Chait where he developed algorithms to analyze proteomics data obtained using

mass spectrometry Mass spectrometry (MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a ''mass spectrum'', a plot of intensity as a function of the mass-to-charge ratio. Mass spectrometry is used ...

, developed a statistical method for protein identification, and applied modeling and simulations to optimize proteomics experimental design and study replication in yeast In 1997, Fenyö co-founded the bioinformatics start-up ProteoMetrics, LLC, and served as the President of the company until 2002 during which he developed software systems for automated analysis of large-scale proteomics data.H.I. Field, D. Fenyö, R.C. Beavis, "RADARS, a bioinformatics solution that automates proteome mass spectral analysis, optimises protein identification, and archives data in a relational database", Proteomics. 2 (2002) 36-47. Subsequently, he served as the Director of Proteomics at Genomic Solutions, and as Staff Scientist and Product Manager at Amersham Biosciences and GE Healthcare before returning to

in 2005 and joining the faculty of

NYU New York University (NYU) is a private research university in New York City, New York, United States. Chartered in 1831 by the New York State Legislature, NYU was founded in 1832 by Albert Gallatin as a non-denominational all-male institutio ...

in 2010. Fenyö is a member of the Editorial Advisory Boards of Molecular and Cellular Proteomics and Proteome Science. He serves on the scientific advisory boards of The Global Proteome Machine, BC Proteome Network, Proteome Software, Protein Metrics and Denator AB. He is also a member of the board of directors for US Human Proteome Organization (USHUPO) and serves as the treasurer.

References

{{DEFAULTSORT:Fenyo, David New York University faculty Uppsala University alumni Rockefeller University alumni American pharmacologists Year of birth missing (living people) Living people