Given name
* Cosme (footballer) (1927–2011), Spanish footballer * Cosme Argerich (1758–1820), Argentinian military physician * Cosme Correa ( 1540s), Portuguese nobleman and colonizer of Bombay * Cosme Damián de Churruca y Elorza (1761–1805), Spanish nobleman and soldier * Cosme Damião (1885–1947), Portuguese football player and coach * Cosme de Torres (1510–1570), Spanish Jesuit missionary * Cosme Delgado (died 1596), Portuguese Renaissance composer * Cosme García Sáez (1818–1874), Spanish inventor * Cosme Martins (born 1959), Brazilian painter * Cosmé McMoon (1901–1980), American pianist and composer * Cosme Prenafeta (born 1971), Spanish volleyball player * Cosme Saavedra (1901–1967), Argentine cyclist * Cosme San Martín (died 1906), Chilean painter * Cosme Rivera (born 1976), Mexican boxer * Cosme Torres Espinoza ( 2000s), Cuban diplomat * Cosmé Tura (1430–1495), Italian painter * Cosme de Villiers (1683–1758), French bibliographerSurname
* Eusebia Cosme (1908–1976), Afro-Cuban poetry reciter and actress * Fernando Nascimento Cosme (born 1983), Brazilian futsal player * Gilbert Cosme (born 1975), Puerto Rican wrestler better known by his ring names, El Mesías and Ricky Banderas * Laura Cosme (born 1992), Colombian footballer * Niccolo Cosme (born 1980), Filipino photographer * Pierre Cosme (born 1965), French historian * Wilberto Cosme (born 1984), Colombian professional footballer * Wilma Cosmé (born 1966), a Puerto Rican-American singer better known by her stage name Sa-Fire {{Given name, type=both