''Corynebacterium urealyticum'' is a bacterial species of the genus ''
Corynebacterium
''Corynebacterium'' () is a genus of Gram-positive bacteria and most are aerobe, aerobic. They are bacillus (shape), bacilli (rod-shaped), and in some phases of life they are, more specifically, club (weapon), club-shaped, which inspired the gen ...
''. It is not commonly found in healthy people. It is, however, an important isolate when found in conjunction with a
urinary tract infection. In contrast to acid-producing bacteria like ''
Escherichia coli'', ''C. urealyticum'', as the name implies, secretes the enzyme
urease which can be strong enough to make urine alkaline. This can lead to the formation of struvite calculi or
renal stone
Kidney stone disease, also known as nephrolithiasis or urolithiasis, is a crystallopathy where a solid piece of material (kidney stone) develops in the urinary tract. Kidney stones typically form in the kidney and leave the body in the urine s ...
s. Risk factors associated with this bacterium include immunosuppression, underlying genitourinary disorders, and antibiotic therapy. There are other urease-producing corynebacteria that are associated with urinary tract infections, but ''C. urealyticum'' is the most common.
References
External links
Type strain of ''Corynebacterium urealyticum'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Corynebacterium
Bacteria described in 1992
{{Actinobacteria-stub