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Contamination control is the generic term for all activities aiming to control the existence, growth and proliferation of
contamination Contamination is the presence of a constituent, impurity, or some other undesirable element that spoils, corrupts, infects, makes unfit, or makes inferior a material, physical body, natural environment, workplace, etc. Types of contamination ...
in certain areas. Contamination control may refer to the atmosphere as well as to surfaces, to particulate matter as well as to microbes and to contamination prevention as well as to
decontamination Decontamination (sometimes abbreviated as decon, dcon, or decontam) is the process of removing contaminants on an object or area, including chemicals, micro-organisms or radioactive substances. This may be achieved by chemical reaction, disinfect ...
.


Function

The aim of all contamination control activities is to permanently ensure a sufficient level of cleanliness in controlled environments. This is accomplished by maintaining, reducing, or eradicating viable and non-viable contamination for either sanitary purposes or in order to maintain an efficient rate of production.


Usage

One of the most common environments that incorporates contamination control into its standards protocol is the
cleanroom A cleanroom or clean room is an engineered space, which maintains a very low concentration of airborne particulates. It is well isolated, well-controlled from contamination, and actively cleansed. Such rooms are commonly needed for scientif ...
. There are many preventive procedures in place within a cleanroom environment. They include subjecting cleanroom staff to strict clothing regulations, and there is often a gowning room where the staff can change clothes under
sterile Sterile or sterility may refer to: *Asepsis, a state of being free from biological contaminants * Sterile (archaeology), a sediment deposit which contains no evidence of human activity *Sterilization (microbiology), any process that eliminates or ...
conditions so as to prevent any
particulate Particulates – also known as atmospheric aerosol particles, atmospheric particulate matter, particulate matter (PM) or suspended particulate matter (SPM) – are microscopic particles of solid or liquid matter suspended in the air. The t ...
s from entering from the outside environment. Certain areas in the cleanroom have more stringent measures than others: packaging areas, corridors, gowning rooms and transfer hatches incorporate strict contamination control measures in order to maintain cleanroom standards. Contamination control is also an important asset for industrial
laboratories A laboratory (; ; colloquially lab) is a facility that provides controlled conditions in which scientific or technological research, experiments, and measurement may be performed. Laboratory services are provided in a variety of settings: physici ...
in the
pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and ...
and life science sectors. Other places of use include automotive paint shops, entrances to industrial kitchens and food service providers, many manufacturing areas, and
electronic component An electronic component is any basic discrete device or physical entity in an electronic system used to affect electrons or their associated fields. Electronic components are mostly industrial products, available in a singular form and are n ...
assembly areas. More recently, effective contamination control has been a concern for laboratories and other sensitive environments as a bio-security
crisis management Crisis management is the process by which an organization deals with a disruptive and unexpected event that threatens to harm the organization or its stakeholders. The study of crisis management originated with large-scale industrial and envir ...
measure. Some
bank A bank is a financial institution that accepts deposits from the public and creates a demand deposit while simultaneously making loans. Lending activities can be directly performed by the bank or indirectly through capital markets. Becau ...
s and
insurance Insurance is a means of protection from financial loss in which, in exchange for a fee, a party agrees to compensate another party in the event of a certain loss, damage, or injury. It is a form of risk management, primarily used to hedge ...
companies use contamination control products as part of their
disaster management Emergency management or disaster management is the managerial function charged with creating the framework within which communities reduce vulnerability to hazards and cope with disasters. Emergency management, despite its name, does not actual ...
protocols. Preventive measures are devised as preparation for combating potential
pandemics A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic disease with a stable number of i ...
or the proliferation of
biohazard A biological hazard, or biohazard, is a biological substance that poses a threat to the health of living organisms, primarily humans. This could include a sample of a microorganism, virus or toxin that can adversely affect human health. A bioh ...
s in any potential terrorist attack.


Types of contamination

Beside particulate matter such as ions and molecules, the most common types of contamination are: * People – Hair, fibre particles from bodies and clothes, also poor hygiene leading to deposition of microorganisms * Environment – Dust particles, contaminated air, work surfaces, gases, movement ceilings, walls and floors * Materials – Micro organisms on packaging, packaging also creates particles, fibres, dust. * Equipment – Moving parts shavings drive belts. * Buildings – Paint flaking, rusty pipe work, poorly maintained surfaces. * Water – Micro organisms grow in water. equipment not cleaned correctly left in a damp condition, spills not mopped up properly etc. Many types organisms are potentially detrimental to processes in a critical environment. Seven of the most common contaminants are: *''
Aspergillus niger ''Aspergillus niger'' is a mold classified within the ''Nigri'' section of the ''Aspergillus'' genus. The ''Aspergillus'' genus consists of common molds found throughout the environment within soil and water, on vegetation, in fecal matter, on de ...
'' *'' Burkholderia cepacia'' *'' Clostridium difficile'' *''
Escherichia coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus '' Esc ...
'' * Methicillin resistant ''Staphylococcus aureus'' (MRSA) *''
Pseudomonas aeruginosa ''Pseudomonas aeruginosa'' is a common encapsulated, gram-negative, aerobic– facultatively anaerobic, rod-shaped bacterium that can cause disease in plants and animals, including humans. A species of considerable medical importance, ''P. aer ...
'' *''
Salmonella enteritidis ''Salmonella enterica'' subsp. ''enterica'' is a subspecies of ''Salmonella enterica'', the rod-shaped, flagellated, aerobic, Gram-negative bacterium. Many of the pathogenic serovars of the ''S. enterica'' species are in this subspecies, includi ...
'' These and many other damaging contaminants can infiltrate critical areas in a number of ways.
Particulates Particulates – also known as atmospheric aerosol particles, atmospheric particulate matter, particulate matter (PM) or suspended particulate matter (SPM) – are microscopic particles of solid or liquid matter suspended in the air. The ...
can enter by air, or on the feet of any carrier moving between the external environment and inside the critical area, for example.


The effects of contamination

Contamination poses a significant risk to technical processes, experiments or production activities, as well as to the individuals involved. Unguarded proliferation of contamination can quickly lead to product damage, yield reduction,
product recall A product recall is a request from a manufacturer to return a product after the discovery of safety issues or product defects that might endanger the consumer or put the maker/seller at risk of legal action. The recall is an effort to limit ruin ...
s and other outcomes highly detrimental to business. Products in a range of industries are recalled due to ineffective contamination control systems. Based on this evidence it could be argued that many businesses are not adequately protecting themselves from the harmful effects of contamination, and many products in many industries are being recalled due to unsafe manufacturing processes.


Types

Body movement causes contamination, and protective clothing such as hats,
cleanroom suit A cleanroom suit, clean room suit, or bunny suit, is an overall garment worn in a cleanroom, an environment with a controlled level of contamination. One common type is an all-in-one coverall worn by semiconductor and nanotechnology line product ...
s and
face mask The face is the front of an animal's head that features the eyes, nose and mouth, and through which animals express many of their emotions. The face is crucial for human identity, and damage such as scarring or developmental deformities may aff ...
s are accordingly basic items of contamination control. Apart from people, another common way for contamination to enter is on the wheels of trolleys used to transport equipment. To prevent airborne contamination, high-efficiency particulate air (
HEPA HEPA (, high-efficiency particulate air) filter, also known as high-efficiency particulate absorbing filter and high-efficiency particulate arrestance filter, is an efficiency standard of air filters. Filters meeting the HEPA standard must ...
) filters, airlocks and cleanroom suits are used. HEPA filtration systems used in the medical sector incorporate high-energy ultraviolet light units to kill the live bacteria and viruses trapped by the filter media. These measures restrict the number of particulates within the atmosphere and inhibit the growth of those that are viable.


Sticky mats

Studies by 3M show that over 80% of contamination enters the cleanroom through entrances and exits, mostly at or near floor level. To combat this problem, suitable flooring systems are used that effectively attract, retain and inhibit the growth of viable organisms. Studies show that the most effective type of flooring system is one of polymer composition. Polymer mats are particularly effective due to their suppleness as they allow for more contact with serrations on shoes and wheels and can accommodate more particles while still remaining effective. An
electrostatic potential Electrostatics is a branch of physics that studies electric charges at rest (static electricity). Since classical times, it has been known that some materials, such as amber, attract lightweight particles after rubbing. The Greek word for ambe ...
adds to the effectiveness of this type of contamination control as it enables particles to be retained until the flooring is cleaned. This method of attracting and retaining particles is more effective than mats with an active adhesive coating which needs to be peeled and is often not as supple. As long as the tack level of the mat is greater than the donor's (such as a foot or a wheel), the contamination touching the surface will be removed. Very high tack surfaces pose a contamination threat because they are prone to pulling off overshoe protection. Polymeric flooring is produced to ensure a higher level of tackiness than the surfaces it comes into contact with, without causing discomfort and potentially damaging 'stickiness'.


Copper alloy surfaces

Copper-alloy surfaces have intrinsic properties which effectively and quickly destroy microbes and they are being installed in healthcare facilities and in a subway transit system as a protective public health measure in addition to regular cleaning. The
United States Environmental Protection Agency The Environmental Protection Agency (EPA) is an independent executive agency of the United States federal government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it ...
(EPA) has approved the registration of 355 different antibacterial copper alloys that kill '' E. coli'' O157:H7, ''
methicillin Methicillin ( USAN), also known as meticillin (INN), is a narrow-spectrum β-lactam antibiotic of the penicillin class. Methicillin was discovered in 1960. Medical uses Compared to other penicillins that face antimicrobial resistance du ...
''-resistant ''
Staphylococcus aureus ''Staphylococcus aureus'' is a Gram-positive spherically shaped bacterium, a member of the Bacillota, and is a usual member of the microbiota of the body, frequently found in the upper respiratory tract and on the skin. It is often posit ...
'' (''
MRSA Methicillin-resistant ''Staphylococcus aureus'' (MRSA) is a group of Gram-positive bacteria that are genetically distinct from other strains of ''Staphylococcus aureus''. MRSA is responsible for several difficult-to-treat infections in humans. ...
''), ''