is a drug manufacturer operating in Japan. It is a subsidiary controlled by
Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche (), is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on ...
, which owns 62% of the company as of 30 June 2014. The company is headquartered in Tokyo.
Osamu Nagayama
is a Japanese businessman. He was the chairman and chief executive officer of Chugai Pharmaceutical Co., one of Japan's largest drug companies.
He served as chairman of the board of directors of Sony Corporation from 2013 to 2019.
In July 2020 ...
is the current representative director and chairman. Tatsuro Kosaka is the current representative director, president and
CEO
A chief executive officer (CEO), also known as a chief executive or managing director, is the top-ranking corporate officer charged with the management of an organization, usually a company or a nonprofit organization.
CEOs find roles in variou ...
.
History
Timeline
This is a timeline of important events of Chugai Pharmaceutical.
[ ]
* 1925: Juzo Ueno founded Chugai Shinyaku Co. Ltd. and started importing and selling medicines
* 1927: Start of the first own production
* 1930: Salobrocanon, an analgesic (pain reliever ) and antipyretic, is launched
* 1937: Calcium bromide production begins
* 1943: Name changed to Chugai Pharmaceutical Co., Ltd. based in Tokyo
* 1944: Acquisition of Matsunaga Pharmaceutical Ltd. and construction of a plant in Matsunaga
* 1945: The headquarters, the factories in Ikebukuro, Sakai and Takada were destroyed in World War II, the headquarters were relocated to Takada, the factory in Takada was rebuilt
* 1946: Construction of the plant in Kamagiishi
* 1951: Guronsan, a drug to detoxify and restore liver function, is launched
* 1952: Varsan, a perspiration insecticide, is launched
* 1955: Chugai became a public company.
* 1956: The stock is listed on the Tokyo Stock Exchange
* 1957: Construction of the Ukima plant
* 1960: Establishment of a research center (Takada Research Laboratory, Tokyo)
* 1967: Foundation of Fukushima Kasai Co Ltd.
* 1961 – Developed patents for synthesis of
vitamin A
Vitamin A is a fat-soluble vitamin that is an essential nutrient. The term "vitamin A" encompasses a group of chemically related organic compounds that includes retinol, retinyl esters, and several provitamin (precursor) carotenoids, most not ...
* 1969: The name of Fukushima Kasai Co Ltd. is changed to Eiko Kasei Co Ltd., after the merger of Fukushima Kasai Co Ltd. and Fukuma Kasau Co. Ltd.
* 1971: Construction of the factory in Fujieda
* 1975: Picibanil, a cancer drug, is launched
* 1982: Opening of a branch in New York
* 1986: Opening of a branch in London
* 1989: Acquisition of Gen-Probe Incorporated (USA)
* 1990: Epogin launched
* 1995 – Released acute promyelocytic sphere of
leukemia
Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' ...
drug treatment
Vesanoid
* 1996 – Released anti-viral chemotherapeutic agent
Hivid (
HIV
The human immunodeficiency viruses (HIV) are two species of '' Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the im ...
reverse transcriptase inhibitor)
* 1997 – Released HIV protease inhibitor
Invirase
* 1999 – Released
immunosuppressive agent
Cellcept
* 2000 – Released
antiemetic
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may ...
drug
Kytril, developed to combat the side effects of
chemotherapy
Chemotherapy (often abbreviated chemo, sometimes CTX and CTx) is the type of cancer treatment that uses one or more anti-cancer drugs (list of chemotherapeutic agents, chemotherapeutic agents or alkylating agents) in a standard chemotherapy re ...
* 2001 – Produced anti-
influenza virus
''Orthomyxoviridae'' () is a family of negative-sense RNA viruses. It includes nine genera: '' Alphainfluenzavirus'', '' Betainfluenzavirus'', '' Gammainfluenzavirus'', '' Deltainfluenzavirus'', '' Isavirus'', '' Mykissvirus'', '' Quaranjavir ...
Tamiflu
Oseltamivir, sold under the brand name Tamiflu among others, is an antiviral medication used to treat and prevent influenza A and influenza B, viruses that cause the flu. Many medical organizations recommend it in people who have complicati ...
(Roche)
* 2002: Start of the alliance with Roche
* 2003: Xeloda, a cancer drug, is launched
* 2005: Actemra launched
* 2007: Copegus, an antiviral, Avastin, a cancer drug, and Tarceva, a cancer drug launched
* 2011 – Produced
Actemra, a human IL-6 receptor monoclonal antibody for rheumatoid arthritis
* 2014: Launch of Kadcyla, a cancer drug, Chugai Pharma China Co Ltd. founded
* 2015 – In March the company announced it would co-commercialise
Athersys's
stem cell therapy for
ischemic stroke
Stroke is a medical condition in which poor blood flow to a part of the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop ...
s in Japan. The deal could yield upwards of US$205 million.
* 2016: Cooperation between Osaka University and Chugai
* 2018: Tecentriq, a cancer drug, is launched
* 2020 – FDA approved
satralizumab (Enspryng) for treatment of the
orphan disease neuromyelitis optica
Neuromyelitis optica spectrum disorders (NMOSD) are a spectrum of autoimmune diseases characterized by acute inflammation of the optic nerve (optic neuritis, ON) and the spinal cord ( myelitis).Banerjee S, Butcher R. Rituximab for the Treatment o ...
See also
*
References
External links
Chugai Pharmaceutical Co., Ltd. English version of company homepage
Roche
Pharmaceutical companies based in Tokyo
Companies listed on the Tokyo Stock Exchange
Companies in the Nikkei 225
Japanese companies established in 1943
1943 establishments in Japan
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