CP-154,526 is a potent and selective
antagonist
An antagonist is a character in a story who is presented as the main enemy or rival of the protagonist and is often depicted as a villain.[corticotropin releasing hormone receptor 1
Corticotropin-releasing hormone receptor 1 (CRHR1) is a protein, also known as CRF1, with the latter (CRF1) now being the IUPHAR-recommended name. In humans, CRF1 is encoded by the ''CRHR1'' gene at region 17q21.31, beside micrototubule-associate ...](_b ...<br></span></div> of the <div class=)
developed by
Pfizer
Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered at The Spiral (New York City), The Spiral in Manhattan, New York City. Founded in 184 ...
.
CP-154,526 is under investigation for the potential treatment of
alcoholism
Alcoholism is the continued drinking of alcohol despite it causing problems. Some definitions require evidence of dependence and withdrawal. Problematic use of alcohol has been mentioned in the earliest historical records. The World He ...
.
See also
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Antalarmin
Antalarmin (CP-156,181) is a drug that acts as a Corticotropin releasing hormone receptor 1, CRH1 antagonist.
Corticotropin-releasing hormone (CRH), also known as Corticotropin-releasing factor family, Corticotropin-releasing factor, is an endog ...
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Pexacerfont
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Corticotropin releasing hormone antagonist
References
Further reading
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External links
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Anxiolytics
Corticotropin-releasing hormone antagonists
Pyrrolopyrimidines
Drugs developed by Pfizer
{{Anxiolytic-stub