Conserved oligomeric Golgi complex subunit 7 is a
protein that in humans is encoded by the ''COG7''
gene.
Multiprotein complexes are key determinants of
Golgi apparatus structure and its capacity for
intracellular transport and glycoprotein modification. Several complexes have been identified, including the
Golgi transport complex The Conserved oligomeric Golgi complex (COG) is a multiprotein complex found in the Golgi apparatus structure and involved in intracellular transport and glycoprotein modification.
Earlier names for this complex were : the Golgi transport complex ( ...
(GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the
conserved oligomeric Golgi (COG) complex, which includes COG7 (Ungar et al., 2002).
upplied by OMIMref name="entrez"/>
Interactions
COG7 has been shown to
interact with
COG4
Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the ''COG4'' gene.
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modif ...
and
COG5
Conserved oligomeric Golgi complex subunit 5 is a protein that in humans is encoded by the ''COG5'' gene.
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein mod ...
.
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References
Further reading
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External links
GeneReviews/NCBI/NIH/UW entry on Congenital Disorders of Glycosylation Overview
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