Chromatin assembly factor 1 subunit A is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
that in humans is encoded by the ''CHAF1A''
gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protei ...
.
Function
Chromatin assembly factor I (
CAF-1) is a nuclear complex consisting of p50, p60 (
CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone tetramers onto replicating DNA in vitro (Kaufman et al., 1995).
upplied by OMIMref name="entrez" />
Interactions
CHAF1A has been shown to
interact with:
*
ASF1A,
[
* ASF1B,]
References
Further reading
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External links
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