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Brodmann area 44, or BA44, is part of the
frontal Front may refer to: Arts, entertainment, and media Films * ''The Front'' (1943 film), a 1943 Soviet drama film * ''The Front'', 1976 film Music * The Front (band), an American rock band signed to Columbia Records and active in the 1980s and e ...
cortex Cortex or cortical may refer to: Biology * Cortex (anatomy), the outermost layer of an organ ** Cerebral cortex, the outer layer of the vertebrate cerebrum, part of which is the ''forebrain'' *** Motor cortex, the regions of the cerebral cortex i ...
in the
human brain The human brain is the central organ of the human nervous system, and with the spinal cord makes up the central nervous system. The brain consists of the cerebrum, the brainstem and the cerebellum. It controls most of the activities of the ...
. Situated just anterior to
premotor cortex The premotor cortex is an area of the motor cortex lying within the frontal lobe of the brain just anterior to the primary motor cortex. It occupies part of Brodmann's area 6. It has been studied mainly in primates, including monkeys and humans. ...
( BA6) and on the lateral surface, inferior to BA9. This area is also known as pars opercularis (of the inferior frontal gyrus), and it refers to a subdivision of the cytoarchitecturally defined frontal region of cerebral cortex. In the human it corresponds approximately to the opercular part of the inferior frontal gyrus. Thus, it is bounded caudally by the inferior precentral sulcus (H) and rostrally by the anterior ascending limb of
lateral sulcus In neuroanatomy, the lateral sulcus (also called Sylvian fissure, after Franciscus Sylvius, or lateral fissure) is one of the most prominent features of the human brain. The lateral sulcus is a deep fissure in each hemisphere that separates the ...
(H). It surrounds the diagonal sulcus (H). In the depth of the lateral sulcus it borders on the insula. Cytoarchitectonically it is bounded caudally and dorsally by the agranular frontal area 6, dorsally by the granular frontal area 9 and rostrally by the triangular part of inferior frontal gyrus (
Brodmann area 45 Brodmann area 45 (BA45), is part of the Frontal lobe, frontal Cerebral cortex, cortex in the human brain. It is situated on the lateral surface, inferior to Brodmann area 9, BA9 and adjacent to Brodmann area 46, BA46. This area in humans occupies ...
BA 45).


Functions

Together with left-hemisphere BA45, the left hemisphere BA44 comprises
Broca's area Broca's area, or the Broca area (, also , ), is a region in the frontal lobe of the dominant Cerebral hemisphere, hemisphere, usually the left, of the Human brain, brain with functions linked to speech production. Language processing in the brai ...
, a region involved in semantic tasks. Some data suggest that BA44 is more involved in the motor aspect of speech. Some recent findings also suggest the implication of this region in
music perception ''Music Perception: An Interdisciplinary Journal'' is a peer-reviewed academic journal published by University of California Press five times a year. It was founded by Diana Deutsch. According to the ''Journal Citation Reports'', the journal has ...
. Recent neuroimaging studies show BA44 involvement in selective response suppression in go/no- go tasks and is therefore believed to play an important role in the suppression of response tendencies., this may apply mainly to the right BA44. Neuroimaging studies also demonstrate that area 44 is related to hand movements. The presence of mirror neurons in Broca's area suggests language evolved from a gesture imitating system. Broca's area is also involved with
theory of mind In psychology, theory of mind refers to the capacity to understand other people by ascribing mental states to them (that is, surmising what is happening in their mind). This includes the knowledge that others' mental states may be different fro ...
(ToM), which is the ability to understand the mental state of others through observation, inferring, and projecting.


Trivia

Scott Flansburg of San Diego, California is a "human calculator" who can perform complex arithmetic in his head. Profiled on the TV show
Stan Lee's Superhumans ''Stan Lee's Superhumans'' is a documentary television series that debuted from August 5, 2010 to September 17, 2014 on History. It is hosted by Marvel comic book superhero creator Stan Lee and follows contortionist Daniel Browning Smith, "th ...
, his brain was scanned using
fMRI Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...
while doing complex calculations, which showed brain activity in this region was absent. Instead there was activity somewhat higher than that of area 44 and closer to the
motor cortex The motor cortex is the region of the cerebral cortex believed to be involved in the planning, control, and execution of voluntary movements. The motor cortex is an area of the frontal lobe located in the posterior precentral gyrus immediately a ...
."Electro Man: Episode 101". Stan Lee's Superhumans. August 5, 2011.


Image

File:Brodmann area 44 animation small.gif, Animation. File:Brodmann area 44 frontal.jpg, Frontal view. File:Brodmann area 44 lateral.jpg, Lateral view.


See also

*
Brodmann area A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. History Brodmann areas were originally defined and numbered by th ...
*
List of regions in the human brain The human brain anatomical regions are ordered following standard neuroanatomy hierarchies. Functional, connective, and developmental regions are listed in parentheses where appropriate. Hindbrain (rhombencephalon) Myelencephalon * Med ...


Notes and references


External links

* For Neuroanatomy of this area visi
BrainInfo
{{DEFAULTSORT:Brodmann Area 44 44 Frontal lobe