Brunó Ferenc Straub (5 January 1914 in
Nagyvárad
Oradea (, , ; ; ) is a city in Romania, located in the Crișana region. It serves as the administrative county seat, seat of Bihor County and an economic, social, and cultural hub in northwestern Romania. The city lies between rolling hills on ...
, Austria-Hungary (now
Oradea
Oradea (, , ; ; ) is a city in Romania, located in the Crișana region. It serves as the administrative county seat, seat of Bihor County and an economic, social, and cultural hub in northwestern Romania. The city lies between rolling hills on ...
,
Romania
Romania is a country located at the crossroads of Central Europe, Central, Eastern Europe, Eastern and Southeast Europe. It borders Ukraine to the north and east, Hungary to the west, Serbia to the southwest, Bulgaria to the south, Moldova to ...
) – 15 February 1996) was a
biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
. As a young scholar he was a research assistant of
Albert Szent-Györgyi
Albert Imre Szent-Györgyi de Rapoltu Mare, Nagyrápolt (; September 16, 1893 – October 22, 1986) was a Hungarian biochemist who won the Nobel Prize in Physiology or Medicine in 1937. He is credited with first isolating vitamin C and disc ...
at the
University of Szeged
The University of Szeged () is a Public university, public research university in Szeged, Hungary. Established as the Jesuit Academy of Kolozsvár in present-day Cluj-Napoca in 1581, the institution was re-established as a university in 1872 by ...
, and subsequently worked at the
Molteno Institute,
Cambridge
Cambridge ( ) is a List of cities in the United Kingdom, city and non-metropolitan district in the county of Cambridgeshire, England. It is the county town of Cambridgeshire and is located on the River Cam, north of London. As of the 2021 Unit ...
, UK. He was the first to obtain
actin
Actin is a family of globular multi-functional proteins that form microfilaments in the cytoskeleton, and the thin filaments in muscle fibrils. It is found in essentially all eukaryotic cells, where it may be present at a concentration of ...
in a relatively pure state. He founded the
Biological Research Centre in
Szeged
Szeged ( , ; see also #Etymology, other alternative names) is List of cities and towns of Hungary#Largest cities in Hungary, the third largest city of Hungary, the largest city and regional centre of the Southern Great Plain and the county seat ...
. He was the
chairman of the Hungarian Presidential Council from 29 June 1988 to 23 October 1989. He proposed the theory of
conformational selection in 1964, the same year the
Monod–Wyman–Changeux model was proposed.
References
{{DEFAULTSORT:Straub, Bruno Ferenc
1914 births
1996 deaths
People from Oradea
Members of the National Assembly of Hungary (1985–1990)
Members of the German Academy of Sciences at Berlin
Hungarian biochemists
Members of the Royal Swedish Academy of Sciences