Baicalin-beta-D-glucuronidase (, ''baicalinase'') is an
enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different mol ...
with
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
''5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase''.
This enzyme
catalyses the following
chemical reaction
A chemical reaction is a process that leads to the chemistry, chemical transformation of one set of chemical substances to another. When chemical reactions occur, the atoms are rearranged and the reaction is accompanied by an Gibbs free energy, ...
:
baicalin
As baicalin is a flavone glycoside, it is a flavonoid. It is the glucuronide of baicalein.
Natural occurrences
Baicalin is found in several species in the genus ''Scutellaria'', including ''Scutellaria baicalensis'', and ''Scutellaria laterifl ...
+ H
2O
baicalein
Baicalein (5,6,7-trihydroxyflavone) is a flavone, a type of flavonoid, originally isolated from the roots of '' Scutellaria baicalensis'' and '' Scutellaria lateriflora''. It is also a constituent of '' Oroxylum indicum'' (Indian trumpetflower) ...
+ D-
glucuronate
Glucuronic acid (GCA, from ) is a uronic acid that was first isolated from urine (hence the name "uronic acid"). It is found in many gums such as gum arabic ( 18%), xanthan, and kombucha tea and is important for the metabolism of microorganis ...
The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency.
References
External links
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