BeeBase is an online bioinformatics database that displays data related to ''
Apis mellifera
The western honey bee or European honey bee (''Apis mellifera'') is the most common of the 7–12 species of honey bees worldwide. The genus name ''Apis'' is Latin for "bee", and ''mellifera'' is the Latin for "honey-bearing" or "honey carrying", ...
'', the European honey bee along with some pathogens and other species. It was developed in collaboration with the
Honey Bee Genome Sequencing Consortium.
[BeeBase website - http://hymenopteragenome.org/beebase/] In 2020 it was archived and replaced by the
Hymenoptera Genome Database The Hymenoptera Genome Database (HGD) is a comprehensive resource supporting genomics of Hymenoptera
Hymenoptera is a large order (biology), order of insects, comprising the sawfly, sawflies, wasps, bees, and ants. Over 150,000 living species of ...
.
Data
The site hosts the genome sequence for ''apis mellifera'' along with those of the following pathogens:
* ''
Bombus terrestris
''Bombus terrestris'', the buff-tailed bumblebee or large earth bumblebee, is one of the most numerous bumblebee species in Europe. It is one of the main species used in greenhouse pollination, and so can be found in many countries and areas wh ...
''
* ''
Bombus impatiens
''Bombus impatiens'', the common eastern bumble bee, is the most commonly encountered bumblebee across much of eastern North America. They can be found in the Eastern temperate forest region of the eastern United States, southern Canada, and t ...
''
Two additional species are under analysis:
* ''
Apis dorsata
''Apis dorsata'', the giant honey bee, सिङ्गुस in Nepali, is a honey bee of South and Southeast Asia, found mainly in forested areas such as the Terai of Nepal. They are typically around long. Nests are mainly built in exposed pla ...
''
* ''
Apis florea
The dwarf honey bee (or red dwarf honey bee), ''Apis florea'', is one of two species of small, wild honey bees of southern and southeastern Asia. It has a much wider distribution than its sister species, '' Apis andreniformis''. First identified ...
''
In Feb 2007, ''BeeBase'' consisted of a
GBrowser-based genome viewer and a
CMap-based] comparative map viewer, both modules of the
Generic Model Organism Database
The Generic Model Organism Database (GMOD) project provides biological research communities with a toolkit of open-source software components for visualizing, annotating, managing, and storing biological data. The GMOD project is funded by the Unit ...
(GMOD) project. The genome viewer included tracks for known honey bee genes, predicted gene sets (Ensembl, NCBI, EMBL-Heidelberg), STS markers (Solignac and Hunt linkage maps), honey bee expressed sequence tags (ESTs), homologs in
fruit fly
Fruit fly may refer to:
Organisms
* Drosophilidae, a family of small flies, including:
** ''Drosophila'', the genus of small fruit flies and vinegar flies
** ''Drosophila melanogaster'' or common fruit fly
** '' Drosophila suzukii'' or Asian fruit ...
,
mosquito
Mosquitoes (or mosquitos) are members of a group of almost 3,600 species of small flies within the family Culicidae (from the Latin ''culex'' meaning "gnat"). The word "mosquito" (formed by ''mosca'' and diminutive ''-ito'') is Spanish for "lit ...
and other insects and
transposable element
A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Trans ...
s. The honey bee comparative map viewer displayed linkage maps and the physical map (genome assembly), highlighting markers that are common among maps.
Future enhancements planned for ''BeeBase'' are a
QTL viewer and a
gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. ...
database. The
genome sequence
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding ge ...
will serve as a reference to link these diverse data types.
Biological data and services available on ''BeeBase'' include:
*
DNA and
protein sequence
Protein primary structure is the linear sequence of amino acids in a peptide or protein. By convention, the primary structure of a protein is reported starting from the amino-terminal (N) end to the carboxyl-terminal (C) end. Protein biosynthesi ...
data
* official bee
gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a b ...
set (developed by and hosted at Beebase)
*
genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding ...
browser
* linkage maps
* server to search the honey bee genome using
BLAST
Blast or The Blast may refer to:
*Explosion, a rapid increase in volume and release of energy in an extreme manner
*Detonation, an exothermic front accelerating through a medium that eventually drives a shock front
Film
* ''Blast'' (1997 film), ...
Beebase organized the community annotation of the bee genome in collaboration with
Baylor College
Baylor University is a private Baptist Christian research university in Waco, Texas. Baylor was chartered in 1845 by the last Congress of the Republic of Texas. Baylor is the oldest continuously operating university in Texas and one of the fir ...
of Medicine
Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the ...
Sequencing Center.
References
External links
BeeBase
See also
*
Wormbase
*
Flybase
FlyBase is an online bioinformatics database and the primary repository of genetic and molecular data for the insect family Drosophilidae. For the most extensively studied species and model organism, ''Drosophila melanogaster'', a wide range of d ...
*
Xenbase
Xenbase is a Model Organism Database (MOD), providing informatics resources, as well as genomic and biological data on Xenopus frogs.K. Karimi et al. (2017Xenbase: a genomic, epigenomic and transcriptomic model organism database Nucleic Acids Re ...
Model organism databases
Genome projects
Beekeeping
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