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Adolph Strecker (October 21, 1822 – November 7, 1871) was a German
chemist A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe t ...
who is remembered primarily for his work with amino acids.


Life and work

Strecker was born in Darmstadt, the son of Friedrich Ludwig Strecker, an
archivist An archivist is an information professional who assesses, collects, organizes, preserves, maintains control over, and provides access to records and archives determined to have long-term value. The records maintained by an archivist can consis ...
working for the hessian Grand Duke, and Henriette Amalie Johannette Koch. Adolph Strecker attended school in Darmstadt until 1838 when he changed to the higher Gewerbeschule. After receiving his abitur in 1840, Strecker began studying science at the
University of Giessen University of Giessen, official name Justus Liebig University Giessen (german: Justus-Liebig-Universität Gießen), is a large public research university in Giessen, Hesse, Germany. It is named after its most famous faculty member, Justus von ...
, where
Justus Liebig Justus Freiherr von Liebig (12 May 1803 – 20 April 1873) was a German scientist who made major contributions to agricultural and biological chemistry, and is considered one of the principal founders of organic chemistry. As a professor at the ...
was a professor. In August 1842, Strecker received his PhD and began teaching at a
realschule ''Realschule'' () is a type of secondary school in Germany, Switzerland and Liechtenstein. It has also existed in Croatia (''realna gimnazija''), the Austrian Empire, the German Empire, Denmark and Norway (''realskole''), Sweden (''realskola''), ...
in Darmstadt. He refused one offer to work for Liebig, but in 1846 he accepted another and became Liebig's private assistant at the University of Giessen. Strecker finished his habilitation in 1848 and became a lecturer at the university. Strecker investigated a wide variety of problems in both organic and inorganic chemistry during his time at Giessen. Examples include the molecular masses of
silver Silver is a chemical element with the symbol Ag (from the Latin ', derived from the Proto-Indo-European ''h₂erǵ'': "shiny" or "white") and atomic number 47. A soft, white, lustrous transition metal, it exhibits the highest electrical ...
and
carbon Carbon () is a chemical element with the symbol C and atomic number 6. It is nonmetallic and tetravalent—its atom making four electrons available to form covalent chemical bonds. It belongs to group 14 of the periodic table. Carbon mak ...
, the reactions of
lactic acid Lactic acid is an organic acid. It has a molecular formula . It is white in the solid state and it is miscible with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as nat ...
, the decomposition of
hippuric acid Hippuric acid ( Gr. ''hippos'', horse, ''ouron'', urine) is a carboxylic acid and organic compound. It is found in urine and is formed from the combination of benzoic acid and glycine. Levels of hippuric acid rise with the consumption of phenol ...
by
nitric acid Nitric acid is the inorganic compound with the formula . It is a highly corrosive mineral acid. The compound is colorless, but older samples tend to be yellow cast due to decomposition into oxides of nitrogen. Most commercially available nitri ...
, and the separation of
cobalt Cobalt is a chemical element with the symbol Co and atomic number 27. As with nickel, cobalt is found in the Earth's crust only in a chemically combined form, save for small deposits found in alloys of natural meteoric iron. The free element, p ...
and
nickel Nickel is a chemical element with symbol Ni and atomic number 28. It is a silvery-white lustrous metal with a slight golden tinge. Nickel is a hard and ductile transition metal. Pure nickel is chemically reactive but large pieces are slow ...
. Strecker wanted to leave Giessen for a position at the
University of Berlin Humboldt-Universität zu Berlin (german: Humboldt-Universität zu Berlin, abbreviated HU Berlin) is a German public research university in the central borough of Mitte in Berlin. It was established by Frederick William III on the initiative ...
, but when he heard of an open position at Norway's
University of Christiania The University of Oslo ( no, Universitetet i Oslo; la, Universitas Osloensis) is a public research university located in Oslo, Norway. It is the highest ranked and oldest university in Norway. It is consistently ranked among the top universit ...
, he applied for it and in 1851 became a professor there. While in Norway, Strecker focused on organic chemistry, covering a broad range of topics from organometallic chemistry to natural products. Strecker left Norway on Christian Gottlob Gmelin's death in 1860 to accept the latter's position at the
University of Tübingen The University of Tübingen, officially the Eberhard Karl University of Tübingen (german: Eberhard Karls Universität Tübingen; la, Universitas Eberhardina Carolina), is a public research university located in the city of Tübingen, Baden-W� ...
. There he conducted research on
guanine Guanine () ( symbol G or Gua) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. The guanine nucleoside is c ...
,
xanthine Xanthine ( or ; archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms. Several stimulants are derived from xanthine, including caffeine ...
,
caffeine Caffeine is a central nervous system (CNS) stimulant of the methylxanthine class. It is mainly used recreationally as a cognitive enhancer, increasing alertness and attentional performance. Caffeine acts by blocking binding of adenosine to ...
, and
theobromine Theobromine, also known as xantheose, is the principal alkaloid of '' Theobroma cacao'' (cacao plant). Theobromine is slightly water-soluble (330 mg/L) with a bitter taste. In industry, theobromine is used as an additive and precursor to ...
, and on the very toxic
thallium Thallium is a chemical element with the symbol Tl and atomic number 81. It is a gray post-transition metal that is not found free in nature. When isolated, thallium resembles tin, but discolors when exposed to air. Chemists William Crookes an ...
oxides, which damaged his health severely. He moved to the
University of Würzburg The Julius Maximilian University of Würzburg (also referred to as the University of Würzburg, in German ''Julius-Maximilians-Universität Würzburg'') is a public research university in Würzburg, Germany. The University of Würzburg is one of ...
in 1870, but his first semester was interrupted by the Franco-Prussian War of 1870–1871. Strecker became an officer during the war and returned to the university after it, where he started his last semester. In the summer of 1871 he undertook a recreational holiday in Berchtesgaden,
Bavaria Bavaria ( ; ), officially the Free State of Bavaria (german: Freistaat Bayern, link=no ), is a state in the south-east of Germany. With an area of , Bavaria is the largest German state by land area, comprising roughly a fifth of the total lan ...
, but his health began to deteriorate. Strecker died in
Würzburg Würzburg (; Main-Franconian: ) is a city in the region of Franconia in the north of the German state of Bavaria. Würzburg is the administrative seat of the ''Regierungsbezirk'' Lower Franconia. It spans the banks of the Main River. Würzburg ...
, where he is buried in the Hauptfriedhof.


Strecker synthesis

The Strecker synthesis of amino acids involves the reaction of potassium cyanide, ammonium chloride, and an aldehyde to make an alpha amino acid. The reaction can also be run with ammonia, hydrogen cyanide, and an aldehyde. Because of the relative simplicity of the reactants, the Strecker synthesis has been invoked by those studying both the origin of life and meteoritic amino acids. Also named for Strecker are the Strecker degradation, which involves the conversion of amino acids into imines and then into ketones, and the Strecker sulfite alkylation.


Notable people who taught Strecker

* Justus von Liebig (1803–1873)


Notable students of Strecker

* Georg Zehfuss (de) (1832–1901)


Family

Strecker, while serving as a professor in Norway, returned to Germany for several holidays. During one such visit to Darmstadt, Strecker, on July 3, 1852, married Karoline Auguste Natalie Weber (1852–1853), who died months later – on October 13, 1853. She had given birth on October 2, 1853, to Friederike Caroline Sophie Christiane Natalie Strecker. Adolph Stecker married a second time on September 29, 1855.


References


External links


Adolph Strecker obituary
by Rudolf Wagner from ''Berichte der Deutschen Chemischen Gesellschaft'', 1872, part V, pp. 125–131 * Obituary in the ''Journal of the Chemical Society'', 1872, volume 25, p. 353 * Adolph Strecker by B. Lepsius (1892), ''Allgemeine Deutsche Biographie'', volume 36, Leipzig: Duncker & Humblot – entry for Strecker

– brief biography and two pictures at Tübingen University * ''Regnault-Strecker's kurzes Lehrbuch der Chemie''. Vieweg, Braunschweig 185
Digital edition
by the University and State Library Düsseldorf *
2. Organische Chemie. 1853
*
1. Anorganische Chemie. 3., verb. Aufl. 1855
*
2. Organische Chemie. 2. Aufl.1857
*
1. Anorganische Chemie. 4. Aufl.1858
*
1. Anorganische Chemie. 9., neu bearb. Aufl. / von Johannes Wislicenus. 1877
{{DEFAULTSORT:Strecker, Adolph University of Würzburg faculty University of Tübingen faculty 19th-century German chemists University of Giessen alumni University of Oslo faculty 1822 births 1871 deaths Scientists from Darmstadt