Artturi Virtanen
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Artturi Ilmari Virtanen (; 15 January 1895 – 11 November 1973) was a Finnish chemist and recipient of the 1945
Nobel Prize in Chemistry The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
"for his research and inventions in agricultural and nutrition chemistry, especially for his fodder preservation method". He invented AIV silage which improved milk production and a method of preserving butter, the AIV salt, which led to increased Finnish butter exports.


Personal life

Artturi Ilmari Virtanen was born on 15 January 1895, in
Helsinki Helsinki () is the Capital city, capital and most populous List of cities and towns in Finland, city in Finland. It is on the shore of the Gulf of Finland and is the seat of southern Finland's Uusimaa region. About people live in the municipali ...
,
Finland Finland, officially the Republic of Finland, is a Nordic country in Northern Europe. It borders Sweden to the northwest, Norway to the north, and Russia to the east, with the Gulf of Bothnia to the west and the Gulf of Finland to the south, ...
. He is the son of Kaarlo Virtanen, a railway engine driver and Serafina Isotalo. He completed his school education at the Classical Lyceum in Viipuri, Finland. He married the
botanist Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who s ...
Lilja Moisio (1894-1972) in 1920 and had two sons with her. In 1933, he bought a farm near Helsinki where he tested some of his scientific results in practice. He saw in the overproduction of food only a temporary phenomenon. He lived a simple life, he never had a car of his own, never smoked and never consumed alcohol. He died of pneumonia in November 1973, following a broken femur from a fall few weeks prior. He was buried at the
Hietaniemi Cemetery The Hietaniemi cemetery (, ) is located mainly in the Lapinlahti quarter and partly in the Etu-Töölö district of Helsinki, the capital of Finland. It is the location for Finnish state funeral services and is owned by the Evangelical Luthe ...
.


Academics

Virtanen began his studies at the University of Helsinki in chemistry 1913 earning his Master and in 1918 his PhD in organic chemistry. In 1919 he started to work in the laboratories of
Valio Valio Ltd () is a Finnish manufacturer of dairy products and one of the largest companies in Finland. Valio's products include cheese, powdered ingredients, butter, yogurt and milk. It is Finland's largest milk processor, producing 85% of the c ...
, a large producer of
dairy products Dairy products or milk products are food products made from (or containing) milk. The most common dairy animals are cow, water buffalo, goat, nanny goat, and Sheep, ewe. Dairy products include common grocery store food around the world such as y ...
and became director of the laboratory in 1920. Feeling not fully qualified and following his interest in
botany Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who s ...
and
zoology Zoology ( , ) is the scientific study of animals. Its studies include the anatomy, structure, embryology, Biological classification, classification, Ethology, habits, and distribution of all animals, both living and extinction, extinct, and ...
led him to further scientific education and so he left
Valio Valio Ltd () is a Finnish manufacturer of dairy products and one of the largest companies in Finland. Valio's products include cheese, powdered ingredients, butter, yogurt and milk. It is Finland's largest milk processor, producing 85% of the c ...
and studied at the
ETH Eth ( , uppercase: ⟨Ð⟩, lowercase: ⟨ð⟩; also spelled edh or eð), known as in Old English, is a letter used in Old English, Middle English, Icelandic, Faroese (in which it is called ), and Elfdalian. It was also used in Sca ...
, the
University of Münster The University of Münster (, until 2023 , WWU) is a public research university located in the city of Münster, North Rhine-Westphalia in Germany. With more than 43,000 students and over 120 fields of study in 15 departments, it is Germany's ...
and the
Stockholm University Stockholm University (SU) () is a public university, public research university in Stockholm, Sweden, founded as a college in 1878, with university status since 1960. With over 33,000 students at four different faculties: law, humanities, social ...
he studied
physical chemistry Physical chemistry is the study of macroscopic and microscopic phenomena in chemical systems in terms of the principles, practices, and concepts of physics such as motion, energy, force, time, thermodynamics, quantum chemistry, statistical mech ...
,
soil chemistry Soil chemistry is the study of the Chemistry, chemical characteristics of soil. Soil chemistry is affected by mineral composition, organic matter and Environment (biophysical), environmental factors. In the early 1870s a consulting chemist to the R ...
and
microbiology Microbiology () is the branches of science, scientific study of microorganisms, those being of unicellular organism, unicellular (single-celled), multicellular organism, multicellular (consisting of complex cells), or non-cellular life, acellula ...
. In 1923 in Sweden he worked with Hans von Euler-Chelpin, who was awarded with the
Nobel Prize in Chemistry The Nobel Prize in Chemistry () is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outst ...
in 1929. Back in Finland he became lecturer at the University of Helsinki in 1924, known for his lectures on chemistry of life. He worked in the laboratory of the Butter Export Association, which became a laboratory of the university. In 1930 the Institute for Biochemistry was founded and Virtanen stayed there until his death in 1973. He became professor of biochemistry at the
Helsinki University of Technology Helsinki University of Technology (TKK; ; , HUT in international usage) was a technical university in Finland. It was located in Otaniemi, Espoo in the Helsinki metropolitan area, and it was one of the three universities from which the modern d ...
in 1931 and at the
University of Helsinki The University of Helsinki (, ; UH) is a public university in Helsinki, Finland. The university was founded in Turku in 1640 as the Royal Academy of Åbo under the Swedish Empire, and moved to Helsinki in 1828 under the sponsorship of Alexander ...
in 1939.


Career

His research started with work on the
phosphorylation In biochemistry, phosphorylation is described as the "transfer of a phosphate group" from a donor to an acceptor. A common phosphorylating agent (phosphate donor) is ATP and a common family of acceptor are alcohols: : This equation can be writ ...
of
hexose In chemistry, a hexose is a monosaccharide (simple sugar) with six carbon atoms. The chemical formula for all hexoses is , and their molecular weight is 180.156 g/mol. Hexoses exist in two forms, open-chain or cyclic, that easily convert into ...
s in 1924. He was able to show that phosphorylation is the first step in many fermentation reactions, which was the foundation of the Embden–Meyerhof pathway. In 1925 his interests shifted to the nitrogen-fixing bacteria in the root nodules of
leguminous Legumes are plants in the pea family Fabaceae (or Leguminosae), or the fruit or seeds of such plants. When used as a dry grain for human consumption, the seeds are also called pulses. Legumes are grown agriculturally, primarily for human consum ...
plants. The improved methods of butter preservation, by adding
disodium phosphate Disodium phosphate (DSP), or disodium hydrogen phosphate, or sodium phosphate dibasic, is an inorganic compound with the chemical formula . It is one of several sodium phosphates. The salt is known in anhydrous form as well as hydrates , where ...
to prevent acidic hydrolysis. This method was in use for several decades in Finland. His research from 1925 till 1932 included the invention of a fodder preservation method ( AIV fodder). The method, patented in 1932, was basically a kind of
silage Silage is fodder made from green foliage crops which have been preserved by fermentation (food), fermentation to the point of souring. It is fed to cattle, sheep and other ruminants. The fermentation and storage process is called ''ensilage'', ' ...
that improved the storage of green fodder, which is important during long winters. The process includes adding dilute hydrochloric or
sulfuric acid Sulfuric acid (American spelling and the preferred IUPAC name) or sulphuric acid (English in the Commonwealth of Nations, Commonwealth spelling), known in antiquity as oil of vitriol, is a mineral acid composed of the elements sulfur, oxygen, ...
to newly stored grain. Increased acidity stops harmful fermentation and has no adverse effect on the nutritive value of the fodder or the animals it is fed to. In 1945, Virtanen received the
Nobel Prize The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred N ...
in chemistry "for his research and inventions in agricultural and nutrition chemistry". His later years studies included the development of partially synthetic cattle feeds. The nitrogen for the synthesis of
amino acid Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins. Only these 22 a ...
s normally comes from
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metab ...
s in the fodder. A special bacterial environment in the
rumen The rumen, also known as a paunch, is the largest stomach compartment in ruminants. The rumen and the reticulum make up the reticulorumen in ruminant animals. The diverse microbial communities in the rumen allows it to serve as the primary si ...
of cattle allows them to use
urea Urea, also called carbamide (because it is a diamide of carbonic acid), is an organic compound with chemical formula . This amide has two Amine, amino groups (–) joined by a carbonyl functional group (–C(=O)–). It is thus the simplest am ...
and
ammonium salt Ammonium is a modified form of ammonia that has an extra hydrogen atom. It is a positively charged (cationic) molecular ion with the chemical formula or . It is formed by the addition of a proton (a hydrogen nucleus) to ammonia (). Ammonium i ...
s as source for the nitrogen instead of plant proteins like
soybean The soybean, soy bean, or soya bean (''Glycine max'') is a species of legume native to East Asia, widely grown for its edible bean. Soy is a staple crop, the world's most grown legume, and an important animal feed. Soy is a key source o ...
or
meat and bone meal Meat and bone meal (MBM) is a product of the rendering industry. It is typically about 48–52% protein, 33–35% ash, 8–12% fat, and 4–7% water. It is primarily used in the formulation of animal feed to improve the amino acid profile of t ...
. He also headed the Valio Laboratory from 1921 to 1969.


Awards and honours

The prestige conferred by the Nobel Prize brought Virtanen invitations, honorary doctorates and membership in foreign academies of science. He was a member of the Finnish, Norwegian, Swedish, Flemish, Bavarian, and Pontifical Academies of Science, and of the Swedish and Danish Academies of Engineering Sciences. He was an honorary member of learned societies in Finland, Sweden, Austria, Edinburgh, and the US, and received honorary degrees of the Universities of Lund, Paris, Giessen, and Helsinki, the Royal Technical College at Stockholm, and the Finland Institute of Technology. The
asteroid An asteroid is a minor planet—an object larger than a meteoroid that is neither a planet nor an identified comet—that orbits within the Solar System#Inner Solar System, inner Solar System or is co-orbital with Jupiter (Trojan asteroids). As ...
1449 Virtanen, discovered by the renowned Finnish astronomer and physicist
Yrjö Väisälä Yrjö Väisälä (; 6 September 1891 – 21 July 1971) was a Finnish astronomer and physicist. His main contributions were in the field of optics. He was also active in geodetics, astronomy and optical metrology. He had an affectionate ni ...
, was named after him. The lunar crater Virtanen is also named after him.


Gallery


References

* * * *


External links

* including the Nobel Lecture on 12 December 1945 ''The Biological Fixation of Nitrogen and the Preservation of Fodder in Agriculture, and Their Importance to Human Nutrition'' {{DEFAULTSORT:Virtanen, Artturi Ilmari 1895 births 1973 deaths Scientists from Helsinki People from Uusimaa Province (Grand Duchy of Finland) Finnish chemists Finnish inventors Finnish Nobel laureates Nobel laureates in Chemistry Agriculture educators Food scientists University of Helsinki alumni Academic staff of the University of Helsinki Finnish biochemists Recipients of the Pour le Mérite (civil class) Foreign associates of the National Academy of Sciences