Applied Maths NV, a

bioMérieux bioMérieux SA is a French multinational biotechnology company founded and headquartered in Marcy-l'Étoile, France, close to Lyon. bioMérieux is present in 44 countries and serves more than 160 countries through a large network of distribu ...

company headquartered in

Sint-Martens-Latem Sint-Martens-Latem () is a municipality located in the Belgian province of East Flanders, in Belgium. The municipality comprises the towns of Deurle and Sint-Martens-Latem proper. In 2021, Sint-Martens-Latem had a total population of 8,285. The ...

Belgium Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to ...

, is a

bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combin ...

company developing software for the biosciences.

History

Applied Maths was founded in 1992 and gained worldwide recognition with the software GelCompar, used as a standard tool for the normalization and comparative analysis of

electrophoresis Electrophoresis, from Ancient Greek ἤλεκτρον (ḗlektron, "amber") and φόρησις (phórēsis, "the act of bearing"), is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric f ...

patterns (

PFGE Pulsed field gel electrophoresis is a technique used for the separation of large DNA molecules by applying to a gel matrix an electric field that periodically changes direction. Historical background Standard gel electrophoresis techniques for ...

, AFLP,

RAPD RAPD may refer to: * Relative afferent pupillary defect *Random amplification of polymorphic DNA Random amplification of polymorphic DNA (RAPD), pronounced "rapid", is a type of polymerase chain reaction (PCR), but the segments of DNA that are am ...

, REP-PCR and variants, etc.). GelCompar II was released in 1998 to deal with the ever growing amounts of information following the success and expansion of electrophoresis and other fingerprinting techniques in various application fields in

microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, ...

virology Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, th ...

and

mycology Mycology is the branch of biology concerned with the study of fungi, including their genetic and biochemical properties, their taxonomy and their use to humans, including as a source for tinder, traditional medicine, food, and entheogens, a ...

. Following the introduction of the concepts of polyphasic taxonomy and the growing need to combine

genotypic The genotype of an organism is its complete set of genetic material. Genotype can also be used to refer to the alleles or variants an individual carries in a particular gene or genetic location. The number of alleles an individual can have in a ...

phenotypic In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological proper ...

, electrophoresis and sequence information, Applied Maths released in 1996 the software package

BIONUMERICS BioNumerics is a bioinformatics desktop software application that manages Microbiology, microbiological data. It is developed by Applied Maths NV, a bioMérieux company. History BioNumerics was first released in 1998. Pulsenet, PulseNet, a net ...

which still today is a platform for the management, storage and (statistical) analysis of all types of biological data. BIONUMERICS and GelCompar II are used by several networks around the globe, such as PulseNet and CaliciNet, to share and identify strain information. In January 2016, Applied Maths was acquired by

Products

: BIONUMERICS is a commercial suite of 4 configurations used for the analysis of all major applications in bioinformatics: 1D electrophoresis gels,

chromatographic In chemical analysis, chromatography is a laboratory technique for the separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a ...

and

spectrometric A spectrometer () is a scientific instrument used to separate and measure spectral components of a physical phenomenon. Spectrometer is a broad term often used to describe instruments that measure a continuous variable of a phenomenon where the ...

profiles,

phenotype In genetics, the phenotype () is the set of observable characteristics or traits of an organism. The term covers the organism's morphology or physical form and structure, its developmental processes, its biochemical and physiological prop ...

characters,

microarray A microarray is a multiplex lab-on-a-chip. Its purpose is to simultaneously detect the expression of thousands of genes from a sample (e.g. from a tissue). It is a two-dimensional array on a solid substrate—usually a glass slide or silic ...

sequence In mathematics, a sequence is an enumerated collection of objects in which repetitions are allowed and order matters. Like a set, it contains members (also called ''elements'', or ''terms''). The number of elements (possibly infinite) is called ...

s, etc. GelCompar II: GelCompar II is a suite of 5 modules developed for the analysis of fingerprint patterns, covering the normalization, import into a relational database and the comparative analysis. BNServer: BNserver is the web-based platform generally installed between a centrally maintained database and distributed clients using BIONUMERICS, GelCompar II or a web browser to exchange biological information and analysis results. BNServer has been used since the nineties in Food outbreak detection.

Reception

Over 15000 peer-reviewed research articles mention the use of Applied Maths software packages BIONUMERICS or Gelcompar II.Scientific articles using Applied Maths software products
Retrieved 20 June 2014

References

External links

*{{official, http://www.applied-maths.com Biotechnology companies of Belgium Computational science Bioinformatics companies Software companies established in 1992 Biotechnology companies established in 1992 1992 establishments in Belgium Software companies of Belgium Companies based in East Flanders