Antonios Georgios Mikos (born 1960) is a Greek-American biomedical engineer who is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at

Rice University William Marsh Rice University, commonly referred to as Rice University, is a Private university, private research university in Houston, Houston, Texas, United States. Established in 1912, the university spans 300 acres. Rice University comp ...

. He specialises in

biomaterials A biomaterial is a substance that has been engineered to interact with biological systems for a medical purpose – either a therapeutic (treat, augment, repair, or replace a tissue function of the body) or a diagnostic one. The corresponding f ...

drug delivery Drug delivery involves various methods and technologies designed to transport pharmaceutical compounds to their target sites helping therapeutic effect. It involves principles related to drug preparation, route of administration, site-specif ...

, and

tissue engineering Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biolo ...

Education

Mikos completed undergraduate study in engineering at the

Aristotle University of Thessaloniki The Aristotle University of Thessaloniki ( AUTh; ), often called the University of Thessaloniki, is the second oldest tertiary education institution in Greece. Named after the philosopher Aristotle, who was born in Stageira, about east of Thessa ...

(Dipl. Eng., 1983), and pursued a master's and doctorate (M.S. in chemical engineering, 1985 and Ph.D. in chemical engineering, 1988) at

Purdue University Purdue University is a Public university#United States, public Land-grant university, land-grant research university in West Lafayette, Indiana, United States, and the flagship campus of the Purdue University system. The university was founded ...

in the United States. After his doctoral studies, he performed his postdoctoral work at

Massachusetts Institute of Technology The Massachusetts Institute of Technology (MIT) is a Private university, private research university in Cambridge, Massachusetts, United States. Established in 1861, MIT has played a significant role in the development of many areas of moder ...

and the

Harvard Medical School Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the Un ...

Career

Mikos is the Louis Calder Professor of Bioengineering and Chemical and Biomolecular Engineering at Rice University in

Houston, Texas Houston ( ) is the List of cities in Texas by population, most populous city in the U.S. state of Texas and in the Southern United States. Located in Southeast Texas near Galveston Bay and the Gulf of Mexico, it is the county seat, seat of ...

. He is also the Director of the National Institutes of Health Center for Engineering Complex Tissues, Director of the Center for Excellence in Tissue Engineering, and Director of the John W. Cox Laboratory of Biomedical Engineering at Rice University. Mikos’ research centers on developing biomaterial systems for tissue engineering, drug delivery,

gene delivery Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Gene delivery must reach the genome of the host cell to induce gene expression. Successful gene delivery requires the foreign gene deliver ...

, and disease modeling. His has studied cartilage, bone, muscle, and cardiovascular engineering, controlled release platforms for

growth factor A growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation. Usually it is a secreted protein or a steroid hormone. Growth factors are important for ...

s, non-viral vectors, and scaffolds for studying

tumor microenvironment The tumor microenvironment is a complex ecosystem surrounding a tumor, composed of cancer cells, stromal tissue (including blood vessels, immune cells, fibroblasts and signaling molecules) and the extracellular matrix. Mutual interaction between ...

s. In 2021, he began studying 3D printing for tissue engineering and hydrogel systems for bone and cartilage regeneration. He co-authored a textbook entitled ''Biomaterials: The Intersection of Biology and Materials Science''. Mikos founded the journals ''Tissue Engineering Part A'', ''Tissue Engineering Part B: Review'', and ''Tissue Engineering Part C: Methods'' and currently serves as their

editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The editor-in-chief heads all departments of the organization and is held accoun ...

. He also serves on the editorial boards of multiple other journals including Advanced Drug Delivery Reviews, Cell Transplantation, Journal of Biomaterials Science Polymer Edition, Journal of Biomedical Materials Research (Part A and B), and

Journal of Controlled Release The ''Journal of Controlled Release'' is a biweekly peer-reviewed medical journal and the official journal of the Controlled Release Society. The journal covers research on the controlled release and delivery of drugs and other biologically active ...

. He has an annual short course on tissue engineering at Rice University since 1993.

References

{{DEFAULTSORT:Mikos, Antonios 1960 births Living people Greek engineers Greek biochemists American bioengineers People from Thessaloniki Rice University faculty Purdue University College of Engineering alumni Aristotle University of Thessaloniki alumni Members of the United States National Academy of Engineering Corresponding Members of the Academy of Athens (modern) 20th-century American engineers 21st-century American engineers Place of birth missing (living people) Greek emigrants to the United States Presidents of Society for Biomaterials Members of the National Academy of Medicine Engineers from Thessaloniki