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Adolphe Guillaume Vorderman (12 December 1844 – 15 July 1902) was a Dutch
physician A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Med ...
and
scientist A scientist is a person who Scientific method, researches to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engag ...
whose study of the link between polished rice and
beriberi Thiamine deficiency is a medical condition of low levels of thiamine (vitamin B1). A severe and chronic form is known as beriberi. The name beriberi was possibly borrowed in the 18th century from the Sinhalese phrase (bæri bæri, “I canno ...
in the
Dutch East Indies The Dutch East Indies, also known as the Netherlands East Indies (; ), was a Dutch Empire, Dutch colony with territory mostly comprising the modern state of Indonesia, which Proclamation of Indonesian Independence, declared independence on 17 Au ...
in 1897 helped lead to the discovery of
vitamin Vitamins are Organic compound, organic molecules (or a set of closely related molecules called vitamer, vitamers) that are essential to an organism in small quantities for proper metabolism, metabolic function. Nutrient#Essential nutrients, ...
s. In addition, he was an
ornithologist Ornithology, from Ancient Greek ὄρνις (''órnis''), meaning "bird", and -logy from λόγος (''lógos''), meaning "study", is a branch of zoology dedicated to the study of birds. Several aspects of ornithology differ from related discip ...
and
botanist Botany, also called plant science, is the branch of natural science and biology studying plants, especially Plant anatomy, their anatomy, Plant taxonomy, taxonomy, and Plant ecology, ecology. A botanist or plant scientist is a scientist who s ...
.


Biography

Vorderman, who was born in
The Hague The Hague ( ) is the capital city of the South Holland province of the Netherlands. With a population of over half a million, it is the third-largest city in the Netherlands. Situated on the west coast facing the North Sea, The Hague is the c ...
, first travelled to the Dutch East Indies in 1866 as a Naval Medical Officer. In 1871 he joined the Civil Health Department, and was stationed at
Sumenep Sumenep is a regency of the East Java province, Indonesia. It has an area of 2,093.47 square kilometres (808.29 sq mi) and an population of 1,143,002 (comprising 552,127 males and 590,875 females) as at mid 2024.Badan Pusat Statistik, Jakarta, 28 ...
on the island of
Madura is an list of islands of Indonesia, Indonesian island off the northeastern coast of Java. The island comprises an area of approximately (administratively including various smaller islands to the east, southeast and north that are administratively ...
until 1881 when he was transferred to Batavia (now
Jakarta Jakarta (; , Betawi language, Betawi: ''Jakartè''), officially the Special Capital Region of Jakarta (; ''DKI Jakarta'') and formerly known as Batavia, Dutch East Indies, Batavia until 1949, is the capital and largest city of Indonesia and ...
). From 1890 until his death in Batavia, he served as Chief Inspector of the department.


Beriberi study

In 1883, the Dutch government sent
Christiaan Eijkman Christiaan Eijkman ( , , ; 11 August 1858 – 5 November 1930) was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of antineuritic vitamins (thiamine). Together with S ...
to the
Dutch East Indies The Dutch East Indies, also known as the Netherlands East Indies (; ), was a Dutch Empire, Dutch colony with territory mostly comprising the modern state of Indonesia, which Proclamation of Indonesian Independence, declared independence on 17 Au ...
(now
Indonesia Indonesia, officially the Republic of Indonesia, is a country in Southeast Asia and Oceania, between the Indian Ocean, Indian and Pacific Ocean, Pacific oceans. Comprising over List of islands of Indonesia, 17,000 islands, including Sumatra, ...
) to try to determine the cause of and find a cure for beriberi. He noticed that chickens fed polished rice – which is rice which has had its bran removed – developed a similar paralysis in their legs. Before he could follow up on this line of enquiry, ill health forced him to return home to the
Netherlands , Terminology of the Low Countries, informally Holland, is a country in Northwestern Europe, with Caribbean Netherlands, overseas territories in the Caribbean. It is the largest of the four constituent countries of the Kingdom of the Nether ...
. Before leaving he asked his friend Adolphe Vorderman, who was Chief Medical Officer, to continue the research on the link between rice and the disease. Vorderman, who had already noted that beriberi occurred a lot in some prisons, but very little in others, decided to conduct a preliminary survey of the type of rice served in a sample of prisons. When that initial study seemed to confirm a link, he decided to conduct a complete study of all prisons. In 1897, Vorderman visited all of the around 100 prisons on the island of Java. He took samples of the prison rice and examined the prison records to determine the number of beriberi cases. He kept the real purpose of his visits secret so that word did not get around the Chinese rice suppliers and lead them to change the type of rice they provided. Later he conducted blind testing with rice experts to discover the make-up and origin of the rice varieties he found in the prison samples. Vorderman found that, in the prisons using mostly brown rice, the incidence of beriberi was less than 1 in 10,000. In the prisons serving mainly polished white rice, the proportion was 1 in 39. In his published report, he concluded that this marked difference could not be explained by any other nutritional or sanitary factor. Later, others, including Gerrit Grijns, took over the research which ultimately led to the discovery of
vitamins Vitamins are organic molecules (or a set of closely related molecules called vitamers) that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in suff ...
. In the case of beriberi, the vitamin that was lost when the
bran Bran, also known as miller's bran, is the component of a Cereal, cereal grain consisting of the hard layersthe combined aleurone and Fruit anatomy#Pericarp layers, pericarpsurrounding the endosperm. Maize, Corn (maize) bran also includes the p ...
was removed was
thiamin Thiamine, also known as thiamin and vitamin B1, is a vitamin – an essential micronutrient for humans and animals. It is found in food and commercially synthesized to be a dietary supplement or medication. Phosphorylated forms of thiam ...
 – vitamin B1. In a 2007 episode of the
BBC The British Broadcasting Corporation (BBC) is a British public service broadcaster headquartered at Broadcasting House in London, England. Originally established in 1922 as the British Broadcasting Company, it evolved into its current sta ...
genealogical Genealogy () is the study of families, family history, and the tracing of their lineages. Genealogists use oral interviews, historical records, genetic analysis, and other records to obtain information about a family and to demonstrate kin ...
documentary series '' Who Do You Think You Are?'', Carol Vorderman researched her great-grandfather Adolphe. In the episode, the Director of the Eijkman Institute stated his opinion that, had he still been alive at the time, Adolphe Vorderman should have shared the
Nobel Prize in Medicine The Nobel Prize in Physiology or Medicine () is awarded yearly by the Nobel Assembly at the Karolinska Institute, Nobel Assembly at the Karolinska Institute for outstanding discoveries in physiology or medicine. The Nobel Prize is not a single ...
with Eijkman and Sir Frederick Hopkins, who were awarded the prize in 1929 for their vitamin-related work.


Other work

Apart from his nutritional study, Vorderman published papers on local poisons, drugs, foods and birds, and was a collector of botanical specimens. For his work, he was made an honorary
Doctor of Science A Doctor of Science (; most commonly abbreviated DSc or ScD) is a science doctorate awarded in a number of countries throughout the world. Africa Algeria and Morocco In Algeria, Morocco, Libya and Tunisia, all universities accredited by the s ...
by
Utrecht University Utrecht University (UU; , formerly ''Rijksuniversiteit Utrecht'') is a public university, public research university in Utrecht, Netherlands. Established , it is one of the oldest universities in the Netherlands. In 2023, it had an enrollment of ...
. The tree species '' Myristica vordermanni'' was named in his honour by Otto Warburg. Vorderman became a corresponding member of the
Royal Netherlands Academy of Arts and Sciences The Royal Netherlands Academy of Arts and Sciences (, KNAW) is an organization dedicated to the advancement of science and literature in the Netherlands. The academy is housed in the Trippenhuis in Amsterdam. In addition to various advisory a ...
in 1889.


Selected publications

* 1884 'List of the birds from Java'. In: ''Natuurkundig Tijdschrift voor Nederlandsch Indie'' (1884) * 1885 ''Catalogus van eenige chineesche en inlandsche voedingsmiddelen van Batavia'' * 1886 ''Kritische beschouwingen over Dr. C.L. van der Burg's "Materia medica", tevens eene bijdrage tot de kennis van eenige inlandsche geneesmiddelen'' * 1886 ''Malaria te Tandjong-Priok'' * 1888 ''Het journaal van Albert Colfs : eene bijdrage tot de kennis der kleine Soenda-eilanden'' (samen met Albert Colfs) * 1889 ''Les oiseaux de Sumatra et leur présence dans les îles Avoisinantes'') * 1890 ''Eurycoma longifolia Jack de moederplant van "kajoe bidara laut"'' * 1890 ''De vogels van Billiton'' * 1891 'Bijdrage tot de kennis van het Billiton-Maleisch'. In: ''Tijdschrift voor Indische taal-, land- en volkenkunde'' (1891) * 1891 ''Naar de Lampongs: verslag van een togt naar dat gewest in September 1883'' * 1891 ''Over eene vogelcollectie afkomstig van Borneo'' * 1897 ''Onderzoek naar het verband tusschen den aard der rijstvoeding in de gevangenissen op Java en Madoera en het voorkomen van beri-beri onder de geïnterneerden'' * 1898 ''Molukken-vogels'' * 1899 ''Inlandsche namen van eenige madoereesche planten en simplicia''


References


External links

* *
Adolphe Vorderman's 1897 study of beriberi among prison inmates in the Dutch East Indies
{{DEFAULTSORT:Vorderman, Adolphe 1844 births 1902 deaths 19th-century Dutch physicians Physicians from The Hague Members of the Royal Netherlands Academy of Arts and Sciences Dutch public health doctors 19th-century Dutch botanists Dutch ornithologists