5F-ADB-PINACA is a
cannabinoid
Cannabinoids () are several structural classes of compounds found primarily in the ''Cannabis'' plant or as synthetic compounds. The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (delta-9-THC), the primary psychoact ...
designer drug that is an ingredient in some
synthetic cannabis products. It is a potent
agonist
An agonist is a chemical that activates a Receptor (biochemistry), receptor to produce a biological response. Receptors are Cell (biology), cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an R ...
of the
CB1 receptor and
CB2 receptor with
EC50 values of 0.24 nM and 2.1 nM respectively.
Metabolism
Twelve 5F-ADB-PINACA major metabolites were identified in several incubations with cryopreserved human hepatocytes. Major metabolic reactions included oxidative defluorination followed by carboxylation.
Legality
5F-ADB-PINACA is listed in the Fifth Schedule of the Misuse of Drugs Act (MDA) and therefore illegal in Singapore as of May 2015.
See also
*
5F-AB-PINACA
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5F-ADB
*
5F-AMB
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5F-APINACA
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AB-FUBINACA
*
AB-CHFUPYCA
*
AB-CHMINACA
*
AB-PINACA
*
ADB-CHMINACA
*
ADB-FUBINACA
*
ADB-PINACA
*
ADBICA
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APICA
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APINACA
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APP-FUBINACA
*
MDMB-CHMICA
*
MDMB-CHMINACA
*
MDMB-FUBINACA
*
PX-1
*
PX-2
*
PX-3
References
{{Cannabinoids
Cannabinoids
Designer drugs
Indazolecarboxamides
Organofluorides