Acacetin is a 4′- ''O''-methylated flavone of the parent compound

apigenin Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a flavone compound that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Apigenin is abundant in parsl ...

, found in ''

Robinia pseudoacacia ''Robinia pseudoacacia'', commonly known as black locust, is a medium-sized hardwood deciduous tree, belonging to the tribe Robinieae of the legume family Fabaceae. It is native to a few small areas of the United States, but it has been widely pl ...

'' (black locust), ''

Turnera diffusa ''Turnera diffusa'', known as damiana, is a shrub native to southern Texas in the United States, Mexico, Central America, South America, and the Caribbean. It belongs to the family Passifloraceae. Damiana is a relatively small, woody shrub th ...

'' (damiana), ''

Betula pendula ''Betula pendula'', commonly known as silver birch, warty birch, European white birch, or East Asian white birch, is a species of tree in the family (biology), family Betulaceae, native plant, native to Europe and parts of Asia, though in so ...

'' (silver birch), and in the fern '' Asplenium normale''. In plant synthesis the enzyme apigenin 4′-''O''-methyltransferase uses ''S''-adenosyl methionine and 5,7,4′-trihydroxyflavone (apigenin) to produce ''S''-adenosylhomocysteine and 4′-methoxy-5,7-dihydroxyflavone (acacetin). It shows moderate aromatase inhibition.

References

Aromatase inhibitors O-methylated flavones Diols {{aromatic-stub

See also

References