The enzyme 3′-nucleotidase (EC 3.1.3.6) the reaction
:a 3′-ribonucleotide + H
2O
a ribonucleoside + phosphate
This enzyme belongs to the family of
hydrolase
In biochemistry, hydrolases constitute a class of enzymes that commonly function as biochemical catalysts that use water to break a chemical bond:
:\ce \quad \xrightarrowtext\quad \ce
This typically results in dividing a larger molecule into s ...
s, specifically those acting on phosphoric
monoester
In chemistry, an ester is a compound derived from an acid (either organic or inorganic) in which the hydrogen atom (H) of at least one acidic hydroxyl group () of that acid is replaced by an organyl group (R). These compounds contain a distinct ...
bonds. The
systematic name
A systematic name is a name given in a systematic way to one unique group, organism, object or chemical substance, out of a specific population or collection. Systematic names are usually part of a nomenclature.
A semisystematic name or semitrivi ...
is 3′-ribonucleotide phosphohydrolase. Other names in common use include 3′-mononucleotidase, 3′-phosphatase, and 3′-ribonucleotidase. This enzyme participates in
purine
Purine is a heterocyclic aromatic organic compound that consists of two rings (pyrimidine and imidazole) fused together. It is water-soluble. Purine also gives its name to the wider class of molecules, purines, which include substituted puri ...
and
pyrimidine metabolism
Pyrimidine biosynthesis occurs both in the body and through organic synthesis.
''De novo'' biosynthesis of pyrimidine
''De Novo'' biosynthesis of a pyrimidine is catalyzed by three gene products CAD, DHODH and UMPS. The first three enzymes of ...
.
References
*
EC 3.1.3
Enzymes of unknown structure
{{3.1-enzyme-stub