ORTHO-MDMA, also known as 2,3-methylenedioxymethamphetamine (2,3-MDMA), is a
positional isomer of the recreational drug
3,4-MDMA (commonly known as Ecstasy or Molly).
It is a
monoamine transporter
Monoamine transporters (MATs) are proteins that function as integral Cell membrane, plasma-membrane Neurotransmitter transporter, transporters to regulate concentrations of extracellular monoamine neurotransmitters. The three major classes are se ...
(MAT)
substrate
Substrate may refer to:
Physical layers
*Substrate (biology), the natural environment in which an organism lives, or the surface or medium on which an organism grows or is attached
** Substrate (aquatic environment), the earthy material that exi ...
and
inhibitor
Inhibitor or inhibition may refer to:
Biology
* Enzyme inhibitor, a substance that binds to an enzyme and decreases the enzyme's activity
* Reuptake inhibitor, a substance that increases neurotransmission by blocking the reuptake of a neurotransmi ...
similarly to 3,4-MDMA.
However, while showing similar
potency at the
norepinephrine transporter
The norepinephrine transporter (NET), also known as noradrenaline transporter (NAT), is a protein that in humans is encoded by the solute carrier family 6 member 2 (SLC6A2) gene.
NET is a monoamine transporter and is responsible for the sodium ...
(NET), 2,3-MDMA is less potent at the
serotonin transporter
The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein t ...
(SERT).
2,3-MDMA has not been encountered as a
recreational or
designer drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...
.
See also
*
2,3-Methylenedioxyamphetamine (2,3-MDA)
*
1-Naphthylmethcathinone (AMAPN)
References
External links
2,3-MDMA , explore , PiHKAL·info
Methamphetamines
Methylenedioxyphenethylamines
Monoamine releasing agents
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