1,3-Diaminopropane, also known as , is a simple
diamine
A diamine is an amine with two amino groups. Diamines are used as monomers to prepare polyamides, polyimides, and polyureas. The term ''diamine'' refers mostly to Primary (chemistry), primary diamines, as those are the most reactive.
In terms of ...
with the formula H
2N(CH
2)
3NH
2. A colourless liquid with a fishy odor, it is soluble in water and many polar organic solvents. It is isomeric with
1,2-diaminopropane. Both are building blocks in the synthesis of
heterocycles, such as those used in
textile finishing, and
coordination complex
A coordination complex is a chemical compound consisting of a central atom or ion, which is usually metallic and is called the ''coordination centre'', and a surrounding array of chemical bond, bound molecules or ions, that are in turn known as ' ...
es. It is prepared by the amination of
acrylonitrile followed by
hydrogenation
Hydrogenation is a chemical reaction between molecular hydrogen (H2) and another compound or element, usually in the presence of a catalyst such as nickel, palladium or platinum. The process is commonly employed to redox, reduce or Saturated ...
of the resulting
aminopropionitrile.
[Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. ]
The potassium salt was used in the
alkyne zipper reaction.
Known uses of 1,3-diaminopropane are in the synthesis of
piroxantrone and
losoxantrone.
Safety
1,3-Diaminopropane is toxic on skin exposure with an of 177 mg kg
−1 (dermal, rabbit)
References
{{DEFAULTSORT:Diaminopropane, 1,3-
Diamines
NMDA receptor antagonists
1,3-Propanediyl compounds