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Unit Step Function
The Heaviside step function, or the unit step function, usually denoted by or (but sometimes , or ), is a step function named after Oliver Heaviside, the value of which is zero for negative arguments and one for positive arguments. Different conventions concerning the value are in use. It is an example of the general class of step functions, all of which can be represented as linear combinations of translations of this one. The function was originally developed in operational calculus for the solution of differential equations, where it represents a signal that switches on at a specified time and stays switched on indefinitely. Heaviside developed the operational calculus as a tool in the analysis of telegraphic communications and represented the function as . Formulation Taking the convention that , the Heaviside function may be defined as: * a piecewise function: H(x) := \begin 1, & x \geq 0 \\ 0, & x * an indicator function: H(x) := \mathbf_=\mathbf 1_(x) For the alt ...
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Step Function
In mathematics, a function on the real numbers is called a step function if it can be written as a finite linear combination of indicator functions of intervals. Informally speaking, a step function is a piecewise constant function having only finitely many pieces. Definition and first consequences A function f\colon \mathbb \rightarrow \mathbb is called a step function if it can be written as :f(x) = \sum\limits_^n \alpha_i \chi_(x), for all real numbers x where n\ge 0, \alpha_i are real numbers, A_i are intervals, and \chi_A is the indicator function of A: :\chi_A(x) = \begin 1 & \text x \in A \\ 0 & \text x \notin A \\ \end In this definition, the intervals A_i can be assumed to have the following two properties: # The intervals are pairwise disjoint: A_i \cap A_j = \emptyset for i \neq j # The union of the intervals is the entire real line: \bigcup_^n A_i = \mathbb R. Indeed, if that is not the case to start with, a different set of intervals can be picked for ...
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Ramp Function
The ramp function is a unary real function, whose graph is shaped like a ramp. It can be expressed by numerous definitions, for example "0 for negative inputs, output equals input for non-negative inputs". The term "ramp" can also be used for other functions obtained by scaling and shifting, and the function in this article is the ''unit'' ramp function (slope 1, starting at 0). In mathematics, the ramp function is also known as the positive part. In machine learning, it is commonly known as a ReLU activation function or a rectifier in analogy to half-wave rectification in electrical engineering. In statistics (when used as a likelihood function) it is known as a tobit model. This function has numerous applications in mathematics and engineering, and goes by various names, depending on the context. There are differentiable variants of the ramp function. Definitions The ramp function () may be defined analytically in several ways. Possible definitions are: * A ...
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Michaelis–Menten Kinetics
In biochemistry, Michaelis–Menten kinetics, named after Leonor Michaelis and Maud Menten, is the simplest case of enzyme kinetics, applied to enzyme-catalysed reactions involving the transformation of one substrate into one product. It takes the form of a differential equation describing the reaction rate v (rate of formation of product (biology), product P, with concentration p) as a function of a, the concentration of the Enzyme substrate (biology), substrate  A (using the symbols recommended by the IUBMB). Its formula is given by the Michaelis–Menten equation: : v = \frac = \frac V, which is often written as V_\max, represents the limiting rate approached by the system at saturating substrate concentration for a given enzyme concentration. The Michaelis constant K_\mathrm has units of concentration, and for a given reaction is equal to the concentration of substrate at which the reaction rate is half of V. Biochemical reactions involving a single substrate are often ...
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Hill Equation (biochemistry)
In biochemistry and pharmacology, the Hill equation refers to two closely related equations that reflect the binding of Ligand (biochemistry), ligands to macromolecules, as a function of the ligand concentration. A Ligand (biochemistry), ligand is "a substance that forms a complex with a biomolecule to serve a biological purpose", and a macromolecule is a very large molecule, such as a protein, with a complex structure of components. Protein-ligand binding typically changes the structure of the target protein, thereby changing its function in a cell. The distinction between the two Hill equations is whether they measure ''occupancy'' or ''response''. The Hill equation reflects the occupancy of macromolecules: the fraction that is saturated or bound by the Ligand (biochemistry), ligand.For clarity, this article will use the International Union of Basic and Clinical Pharmacology convention of distinguishing between the Hill-Langmuir equation (for receptor saturation) and Hill equat ...
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Logistic Function
A logistic function or logistic curve is a common S-shaped curve ( sigmoid curve) with the equation f(x) = \frac where The logistic function has domain the real numbers, the limit as x \to -\infty is 0, and the limit as x \to +\infty is L. The exponential function with negated argument (e^ ) is used to define the standard logistic function, depicted at right, where L=1, k=1, x_0=0, which has the equation f(x) = \frac and is sometimes simply called the sigmoid. It is also sometimes called the expit, being the inverse function of the logit. The logistic function finds applications in a range of fields, including biology (especially ecology), biomathematics, chemistry, demography, economics, geoscience, mathematical psychology, probability, sociology, political science, linguistics, statistics, and artificial neural networks. There are various generalizations, depending on the field. History The logistic function was introduced in a series of three papers by Pier ...
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Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. Hist ...
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Biochemistry
Biochemistry, or biological chemistry, is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology, and metabolism. Over the last decades of the 20th century, biochemistry has become successful at explaining living processes through these three disciplines. Almost all List of life sciences, areas of the life sciences are being uncovered and developed through biochemical methodology and research.#Voet, Voet (2005), p. 3. Biochemistry focuses on understanding the chemical basis that allows biomolecule, biological molecules to give rise to the processes that occur within living Cell (biology), cells and between cells,#Karp, Karp (2009), p. 2. in turn relating greatly to the understanding of tissue (biology), tissues and organ (anatomy), organs as well as organism structure and function.#Miller, Miller (2012). p. 62. Biochemistry is closely ...
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Constant Random Variable
In probability theory, a degenerate distribution on a measure space (E, \mathcal, \mu) is a probability distribution whose support is a null set with respect to \mu. For instance, in the -dimensional space endowed with the Lebesgue measure, any distribution concentrated on a -dimensional subspace with is a degenerate distribution on . This is essentially the same notion as a singular probability measure, but the term ''degenerate'' is typically used when the distribution arises as a limit of (non-degenerate) distributions. When the support of a degenerate distribution consists of a single point , this distribution is a Dirac measure in : it is the distribution of a deterministic random variable equal to with probability 1. This is a special case of a discrete distribution; its probability mass function equals 1 in and 0 everywhere else. In the case of a real-valued random variable, the cumulative distribution function of the degenerate distribution localized in is ...
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Almost Surely
In probability theory, an event is said to happen almost surely (sometimes abbreviated as a.s.) if it happens with probability 1 (with respect to the probability measure). In other words, the set of outcomes on which the event does not occur has probability 0, even though the set might not be empty. The concept is analogous to the concept of "almost everywhere" in measure theory. In probability experiments on a finite sample space with a non-zero probability for each outcome, there is no difference between ''almost surely'' and ''surely'' (since having a probability of 1 entails including all the sample points); however, this distinction becomes important when the sample space is an infinite set, because an infinite set can have non-empty subsets of probability 0. Some examples of the use of this concept include the strong and uniform versions of the law of large numbers, the continuity of the paths of Brownian motion, and the infinite monkey theorem. The terms almost certai ...
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Random Variable
A random variable (also called random quantity, aleatory variable, or stochastic variable) is a Mathematics, mathematical formalization of a quantity or object which depends on randomness, random events. The term 'random variable' in its mathematical definition refers to neither randomness nor variability but instead is a mathematical function (mathematics), function in which * the Domain of a function, domain is the set of possible Outcome (probability), outcomes in a sample space (e.g. the set \ which are the possible upper sides of a flipped coin heads H or tails T as the result from tossing a coin); and * the Range of a function, range is a measurable space (e.g. corresponding to the domain above, the range might be the set \ if say heads H mapped to -1 and T mapped to 1). Typically, the range of a random variable is a subset of the Real number, real numbers. Informally, randomness typically represents some fundamental element of chance, such as in the roll of a dice, d ...
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Cumulative Distribution Function
In probability theory and statistics, the cumulative distribution function (CDF) of a real-valued random variable X, or just distribution function of X, evaluated at x, is the probability that X will take a value less than or equal to x. Every probability distribution Support (measure theory), supported on the real numbers, discrete or "mixed" as well as Continuous variable, continuous, is uniquely identified by a right-continuous Monotonic function, monotone increasing function (a càdlàg function) F \colon \mathbb R \rightarrow [0,1] satisfying \lim_F(x)=0 and \lim_F(x)=1. In the case of a scalar continuous distribution, it gives the area under the probability density function from negative infinity to x. Cumulative distribution functions are also used to specify the distribution of multivariate random variables. Definition The cumulative distribution function of a real-valued random variable X is the function given by where the right-hand side represents the probability ...
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Integral
In mathematics, an integral is the continuous analog of a Summation, sum, which is used to calculate area, areas, volume, volumes, and their generalizations. Integration, the process of computing an integral, is one of the two fundamental operations of calculus,Integral calculus is a very well established mathematical discipline for which there are many sources. See and , for example. the other being Derivative, differentiation. Integration was initially used to solve problems in mathematics and physics, such as finding the area under a curve, or determining displacement from velocity. Usage of integration expanded to a wide variety of scientific fields thereafter. A definite integral computes the signed area of the region in the plane that is bounded by the Graph of a function, graph of a given Function (mathematics), function between two points in the real line. Conventionally, areas above the horizontal Coordinate axis, axis of the plane are positive while areas below are n ...
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