Trichloroethylene
Trichloroethylene (TCE) is an organochloride with the formula C2HCl3, commonly used as an industrial metal-degreasing solvent. It is a clear, colourless, non-flammable, volatile liquid with a chloroform-like pleasant mild smell and sweet taste.Trichloroethylene (TCE) on ATSDR Its name is trichloroethene. Trichloroethylene has been sold under a variety of trade names. Industrial abbreviations include trichlor, Trike, Tricky and tri. Under the trade names Trimar and Trilene, it was used as a [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tetrachloroethylene
Tetrachloroethylene, also known as perchloroethylene or under the systematic name tetrachloroethene, and abbreviations such as perc (or PERC), and PCE, is a chlorocarbon with the formula . It is a non-flammable, stable, colorless and heavy liquid widely used for dry cleaning of fabrics and occasionally as a highly effective automotive brake cleaner. It has a mildly sweet, sharp odor, detectable by most people at a concentration of 50 ppm. Tetrachloroethylene is regarded as a toxic substance, a human health hazard, and an environmental hazard. In 2020, the United States Environmental Protection Agency stated that "tetrachloroethylene exposure may harm the nervous system, liver, kidneys, and reproductive system, and may be harmful to unborn children", and reported that numerous toxicology agencies regard it as a carcinogen. History and production French chemist Henri Victor Regnault first synthesized tetrachloroethylene in 1839 by thermal decomposition of hexachloroethane f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1,1,1-trichloroethane
1,1,1-Trichloroethane, also known as methyl chloroform and chlorothene, is a chloroalkane with the chemical formula CH3CCl3. It is an isomer of 1,1,2-trichloroethane. A colourless and sweet-smelling liquid, it was once produced industrially in large quantities for use as a solvent. It is regulated by the Montreal Protocol as an ozone-depleting substance and as such use has declined since 1996. Trichloroethane should not be confused with the similar-sounding trichloroethene which is also commonly used as a solvent. Production 1,1,1-Trichloroethane was first reported by Henri Victor Regnault in 1840. Industrially, it is usually produced in a two-step process from vinyl chloride. In the first step, vinyl chloride reacts with hydrogen chloride at 20–50 °C to produce 1,1-dichloroethane: : + HCl → CHCHCl This reaction is catalyzed by a variety of Lewis acids, mainly aluminium chloride, iron(III) chloride, or zinc chloride. The 1,1-dichloroethane is then converted to 1 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Inhalational Anesthetic
An inhalational anesthetic is a chemical compound possessing general anesthetic properties that is delivered via inhalation. They are administered through a face mask, laryngeal mask airway or tracheal tube connected to an anesthetic vaporiser and an anesthetic delivery system. Agents of significant contemporary clinical interest include volatile anesthetic agents such as isoflurane, sevoflurane and desflurane, as well as certain anesthetic gases such as nitrous oxide and xenon. List of inhalational anaesthetic agents Currently-used agents * Desflurane * Isoflurane * Nitrous oxide * Sevoflurane * Xenon Previously-used agents Although some of these are still used in clinical practice and in research, the following anaesthetic agents are primarily of historical interest in developed countries: * Acetylene * Chloroethane (ethyl chloride) * Chloroform * Cryofluorane * Cyclopropane * Diethyl ether * Divinyl ether * Enflurane * Ethylene * Fluroxene * Halothane (still wi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1,1,2-Trichloroethane
1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula and the structural formula . It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture. It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene. Toxicity 1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness. The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health The National Institute for Occupational Safety and Health (NIOSH, ) is the List of United States federal agencies, United States federal agency responsible f ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1,1,2,2-Tetrachloroethane
1,1,2,2-tetrachloroethane (TeCA), also known by the brand names Bonoform, Cellon and Westron, is an organic compound. It is colorless liquid and has a sweet odor. It is used as an industrial solvent and as a separation agent. TeCA is toxic and it can be inhaled, consumed or absorbed through the skin. After exposure, nausea, dizziness or even liver damage may occur. History 1,1,2,2-Tetrachloroethane and 1,1,1,2-Tetrachloroethane were discovered by Auguste Laurent in 1836. 1,1,2,2-tetrachloroethane was used in large amounts to produce other chemicals like trichloroethylene, tetrachloroethylene, and 1,2-dichloroethylene. Because of its possible carcinogen effects on humans, the production of 1,1,2,2-tetrachloroethane has decreased significantly and is no longer widely used as an end-product. It is however still generated as a byproduct and as an intermediate product during manufacturing, where low levels of the chemical have been detected in the air. Uses 1,1,2,2-Tetrachloroethan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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1,1,1,2-Tetrachloroethane
1,1,1,2-Tetrachloroethane is a chlorinated hydrocarbon. It is a colorless liquid with a sweet chloroform-like odor. It is used as a solvent and in the production of wood stains and varnishes. It is an isomer of 1,1,2,2-tetrachloroethane. Production 1,1,1,2-Tetrachloroethane can be obtained by a two-step addition reaction of acetylene with chlorine (via dichloroethene), but this mainly produces 1,1,2,2-tetrachloroethane. : : It can be obtained directly by chlorination of 1,1,2-trichloroethane: : Safety IARC has classified 1,1,1,2-tetrachloroethane as a possible carcinogen for humans in 2014. See also * 1,1,2,2-Tetrachloroethane 1,1,2,2-tetrachloroethane (TeCA), also known by the brand names Bonoform, Cellon and Westron, is an organic compound. It is colorless liquid and has a sweet odor. It is used as an industrial solvent and as a separation agent. TeCA is toxic and it ca ... References {{DEFAULTSORT:Tetrachlorethane, 1, 1, 1, 2- Chloroalkanes Halogenated solvents ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Auguste Laurent
Auguste Laurent (14 November 1807 – 15 April 1853) was a French chemist who helped in the founding of organic chemistry with his discoveries of trichloroethylene, anthracene, phthalic acid, and carbolic acid. He devised a systematic nomenclature for organic chemistry based on structural grouping of atoms within molecules to determine how the molecules combine in organic reactions. He studied under Jean-Baptiste Dumas as a laboratory assistant. At that time, the weight of carbon was considered to be 6. Laurent thought that a weight of 12 was more logical, and started drawing structures on that basis. He published his work in conjunction with Charles Frédéric Gerhardt. Shunned by Dumas, he eked out a living teaching in the mineral engineering lab - where he taught a young Louis Pasteur how to crystalize tartaric acid. Laurent died in Paris from tuberculosis. Alexander Williamson in England read Laurent's writing, leading to the Williamson Ether Synthesis that confirmed t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hexachloroethane
Hexachloroethane (perchloroethane) is an organochlorine compound with the chemical formula . Its structure is . It is a white or colorless solid at room temperature with a camphor-like odor. It has been used by the military in smoke compositions, such as base-eject smoke munitions ( smoke grenades). Hexachloroethane was discovered along with carbon tetrachloride by Michael Faraday in 1820. Faraday obtained it by chlorinating ethylene. Manufacture Chlorination of tetrachloroethylene at 100–140 °C with the presence of iron(III) chloride is the most commonly used commercial production method, however several other methods exist. A high purity form can be produced in a small scale by reacting chlorine together with barium carbide. In September 1997, it was reported as no longer being produced in the United States for commercial distribution, but was produced as a by-product of industrial chlorination process. : Applications Hexachloroethane has been used in the formulation ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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List Of R-phrases
R-phrases (short for risk phrases) are defined in Annex III of European Union Directive 67/548/EEC: ''Nature of special risks attributed to dangerous substances and preparations''. The list was consolidated and republished in Directive 2001/59/EC, where translations into other EU languages may be found. These risk phrases are used internationally, not just in Europe, and there is an ongoing effort towards complete international harmonization using the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) which now generally replaces these risk phrases. Risk phrases Missing R-numbers indicate phrases that have been deleted or replaced by other phrases. Combinations R-phrases no longer in use * : Extremely flammable liquefied gas. * : May cause birth defects. See also * List of S-phrases * Material safety data sheet * Risk and Safety Statements In simple terms, risk is the possibility of something bad happening. Risk involves uncertainty about th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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N-Propyl Bromide
1-Bromopropane (also known as ''n''-propyl bromide or nPB) is a bromoalkane with the chemical formula CH3CH2CH2Br. It is a colorless, flammable liquid that is used as a solvent. It has a characteristic hydrocarbon odor. Its industrial applications increased dramatically in the 21st century due to the phasing out of chlorofluorocarbons and chloroalkanes such as 1,1,1-trichloroethane under the Montreal Protocol. It was also used as a dry cleaning solvent as a substitute for perchloroethylene for a short time in the United States. 1-Bromopropane is highly neurotoxic and possibly carcinogenic to humans. Preparation Industrial routes to 1-bromopropane involve free-radical additions to the corresponding alkenes. In this way, the anti-Markovnikov product is obtained.David Ioffe, Arieh Kampf "Bromine, Organic Compounds" in Kirk-Othmer Encyclopedia of Chemical Technology 2002 by John Wiley & Sons. . Alternatively, ''n''propanol may be substitutively brominated. The latter reaction i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Imperial Chemical Industries
Imperial Chemical Industries (ICI) was a British Chemical industry, chemical company. It was, for much of its history, the largest manufacturer in Britain. Its headquarters were at Millbank in London. ICI was listed on the London Stock Exchange and was a constituent of the FT 30 and later the FTSE 100 Index, FTSE 100 indices. ICI was formed in 1926 as a result of the merger of four of Britain's leading chemical companies. From the onset, it was involved in the production of various chemicals, explosives, fertilisers, insecticides, dyestuffs, non-ferrous metals, and paints; the firm soon become involved in plastics and a variety of speciality products, including food ingredients, polymers, electronic materials, fragrances and flavourings. During the Second World War, ICI's subsidiary Nobel Enterprises, ICI Nobel produced munitions for Britain's war effort; the wider company was also involved with Britain's nuclear weapons programme codenamed Tube Alloys. Throughout the 1940s and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |