Toxicity Class
Toxicity class refers to a classification system for pesticides that has been created by a national or international government-related or -sponsored organization. It addresses the acute toxicity of agents such as soil fumigants, fungicides, herbicides, insecticides, miticides, molluscicides, nematicides, or rodenticides. General considerations Assignment to a toxicity class is based typically on results of acute toxicity studies such as the determination of values in animal experiments, notably rodents, via oral, inhaled, or external application. The experimental design measures the acute death rate of an agent. The toxicity class generally does not address issues of other potential harm of the agent, such as bioaccumulation, issues of carcinogenicity, teratogenicity, mutagenic effects, or the impact on reproduction. Regulating agencies may require that packaging of the agent be labeled with a signal word, a specific warning label to indicate the level of toxicity. By ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Toxicity Labels
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacteria, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell (biology), cell (cytotoxicity) or an organ such as the liver (hepatotoxicity). Sometimes the word is more or less synonymous with poison#Poisoning, poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are Dose (biochemistry), dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypass animal testing, while maintaining the concept of toxicity endpoints. Etymology In Ancient G ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Reproduction
Reproduction (or procreation or breeding) is the biological process by which new individual organisms – "offspring" – are produced from their "parent" or parents. There are two forms of reproduction: Asexual reproduction, asexual and Sexual reproduction, sexual. In asexual reproduction, an organism can reproduce without the involvement of another organism. Asexual reproduction is not limited to unicellular organism, single-celled organisms. The cloning of an organism is a form of asexual reproduction. By asexual reproduction, an organism creates a genetically similar or identical copy of itself. The evolution of sexual reproduction is a major puzzle for biologists. The two-fold cost of sexual reproduction is that only 50% of organisms reproduce and organisms only pass on 50% of their genes.John Maynard Smith ''The Evolution of Sex'' 1978. Sexual reproduction typically requires the sexual interaction of two specialized reproductive cells, called gametes, which contain half t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Globally Harmonized System
The Globally Harmonized System of Classification and Labelling of Chemicals (GHS) is an internationally agreed-upon standard managed by the United Nations that was set up to replace the assortment of hazardous material classification and labelling schemes previously used around the world. Core elements of the GHS include standardized hazard testing criteria, universal warning pictograms, and safety data sheets which provide users of dangerous goods relevant information with consistent organization. The system acts as a complement to the UN numbered system of regulated hazardous material transport. Implementation is managed through the UN Secretariat. Although adoption has taken time, as of 2017, the system has been enacted to significant extents in most major countries of the world. This includes the European Union, which has implemented the United Nations' GHS into EU law as the CLP Regulation, and United States Occupational Safety and Health Administration standards. History Bef ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hazard Symbol
Hazard symbols are universally recognized Symbol, symbols designed to alert individuals to the presence of Hazard, hazardous or dangerous materials, locations, or conditions. These include risks associated with Electromagnetic field, electromagnetic fields, Electrical injury, electric currents, toxic chemicals, Explosive, explosive substances, and Radioactivity, radioactive materials. Their design and use are often governed by laws and standards organizations to ensure clarity and consistency. Hazard symbols may vary in color, background, borders, or accompanying text to indicate specific dangers and levels of risk, such as toxicity classes. These symbols provide a quick, universally understandable visual warning that transcends language barriers, making them more effective than text-based warnings in many situations. List of standardized hazard symbol systems Examples of common symbols Tape with yellow and black diagonal stripes is commonly used as a generic hazard warni ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dangerous Goods
Dangerous goods are substances that are a risk to health, safety, property or the environment during transport. Certain dangerous goods that pose risks even when not being transported are known as hazardous materials ( syllabically abbreviated as HAZMAT or hazmat). An example of dangerous goods is hazardous waste which is waste that threatens public health or the environment. Hazardous materials are often subject to chemical regulations. Hazmat teams are personnel specially trained to handle dangerous goods, which include materials that are radioactive, flammable, explosive, corrosive, oxidizing, asphyxiating, biohazardous, toxic, poisonous, pathogenic, or allergenic. Also included are physical conditions such as compressed gases and liquids or hot materials, including all goods containing such materials or chemicals, or may have other characteristics that render them hazardous in specific circumstances. Dangerous goods are often indicated by diamond-shaped signage on the it ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Restricted Use Pesticides
Restricted use pesticides (RUP) are pesticides not available to the general public in the United States. Fulfilling its pesticide regulation responsibilities, the United States Environmental Protection Agency (EPA) registers all pesticides as either "unclassified" or "restricted use". Unclassified pesticides are available over-the-counter, while the latter require a license to purchase and apply the product. Pesticides are classified as "restricted use" for a variety of reasons, such as potential for or history of groundwater contamination. The RUP classification restricts a product, or its uses, to use by a certificated pesticide applicator or under the direct supervision of a certified applicator. Certification programs are administered by the federal government, individual states, and by company policies that vary from state to state. This is managed by the EPA under the Worker Protection Standard, in cooperation with the United States Department of Agriculture. The RUP list i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Skull And Crossbones (poison)
A skull and crossbones is a symbol consisting of a human skull and two long bones crossed together under or behind the skull. The design originated in the Late Middle Ages as a symbol of death and especially as a ''memento mori'' on tombstones. Actual skulls and bones were long used to mark the entrances to Skull and crossbones (Spanish cemetery), Spanish cemeteries (campo santo). In modern contexts, it is generally used as a hazard symbol, usually in regard to poisonous substances, such as deadly chemicals. It is also associated with piracy and software piracy, due to its historical use in some Jolly Roger flags. Military use The skull and bones are often used in military insignia, such as the coats of arms of regiments. Since the mid-18th century, skull and crossbones insignia has been officially used in European armies as symbols of superiority. One of the first regiments was the Frederick the Great's Hussars in 1741, also known as the "". From this tradition, the skull ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Federal Insecticide, Fungicide, And Rodenticide Act
The Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) is a United States federal law that set up the basic U.S. system of pesticide regulation to protect applicators, consumers, and the environment. It is administered and regulated by the United States Environmental Protection Agency (EPA) and the appropriate environmental agencies of the respective states. FIFRA has undergone several important amendments since its inception. A significant revision in 1972 by the Federal Environmental Pesticide Control Act (FEPCA) and several others have expanded EPA's present authority to oversee the sales and use of pesticides with emphasis on the preservation of human health and protection of the environment by "(1) strengthening the registration process by shifting the burden of proof to the chemical manufacturer, (2) enforcing compliance against banned and unregistered products, and (3) promulgating the regulatory framework missing from the original law". History The Federal ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pesticide Regulation In The United States
Pesticide regulation in the United States is primarily a responsibility of the Environmental Protection Agency (EPA). In America, it was not till the 1950s that pesticides were regulated in terms of their safety. The Pesticides Control Amendment (PCA) of 1954 was the first time Congress passed guidance regarding the establishment of safe limits for pesticide residues on food. It authorized the Food and Drug Administration (FDA) to ban pesticides they determined to be unsafe if they were sprayed directly on food. The Food Additives Amendment, which included the Delaney Clause, prohibited the pesticide residues from any carcinogenic pesticides in processed food. In 1959, pesticides were required to be registered. In 1970, President Richard Nixon created the EPA and shifted control of pesticide regulation from the US Department of Agriculture (USDA), the US Department of the Interior (DOI), and FDA to the newly created agency. By this time, public awareness of potential human hea ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Toxicity Category Rating
In , the EPA established four Toxicity Categories for acute hazards of pesticide products, with "Category I" being the highest toxicity category (toxicity class). Most human hazard, precautionary statements, and human personal protective equipment statements are based upon the Toxicity Category of the pesticide product as sold or distributed. In addition, toxicity categories may be used for regulatory purposes other than labeling, such as classification for restricted use and requirements for child-resistant packaging. In certain cases, statements based upon the Toxicity Category of the product as :wikt:dilute, diluted for use are also permitted. A Toxicity Category is assigned for each of five types of acute exposure, as specified in the table below. Overview The four toxicity categories, from one to four are: *Toxicity category I is highly toxic and severely irritating, *Toxicity category II is moderately toxic and moderately irritating, *Toxicity category III is slightly tox ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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United States Environmental Protection Agency
The Environmental Protection Agency (EPA) is an independent agency of the United States government tasked with environmental protection matters. President Richard Nixon proposed the establishment of EPA on July 9, 1970; it began operation on December 2, 1970, after Nixon signed an executive order. The order establishing the EPA was ratified by committee hearings in the House and Senate. The agency is led by its administrator, who is appointed by the president and approved by the Senate. The current administrator is Lee Zeldin. The EPA is not a Cabinet department, but the administrator is normally given cabinet rank. The EPA has its headquarters in Washington, D.C. There are regional offices for each of the agency's ten regions, as well as 27 laboratories around the country. The agency conducts environmental assessment, research, and education. It has the responsibility of maintaining and enforcing national standards under a variety of environmental laws, in consultat ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Toxicity Label
Toxicity labels viz; red label, yellow label, blue label and green label are mandatory labels employed on pesticide containers in India identifying the level of toxicity (that is, the toxicity class) of the contained pesticide. The schemes follows from the ''Insecticides Act'' of 1968 and the ''Insecticides Rules'' of 1971. The labeling follows a general scheme as laid down in the ''Insecticides Rules, 1971'', and contains information such as brand name, name of manufacturer, name of the antidote in case of accidental consumption etc. A major aspect of the label is a color mark which represents the toxicity of the material by a color code. Thus the labelling scheme proposes four different colour labels: viz red, yellow, blue, and green. The toxicity classification applies only to pesticides which are allowed to be sold in India. Some of the classified pesticides may be banned in some states of India, by decision of the state governments. Some of the red-label and yellow-label ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |