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Registered Report
Preregistration is the practice of registering the hypotheses, methods, or analyses of a scientific study before it is conducted. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration has the goal to transparently evaluate the severity of hypothesis tests,, and can have a number of secondary goals (which can also be achieved without preregistering ), including (a) facilitating and documenting research plans, (b) identifying and reducing questionable research practices and researcher biases, (c) distinguishing between confirmatory and exploratory analyses, and, in the case of Registered Reports, (d) facilitating results-blind peer review, and (e) reducing publication bias. A number of research practices such as p-hacking, publication bias, data dredging, inappropriate forms of po ...
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P-hacking
Data dredging, also known as data snooping or ''p''-hacking is the misuse of data analysis to find patterns in data that can be presented as statistically significant, thus dramatically increasing and understating the risk of false positives. This is done by performing many statistical tests on the data and only reporting those that come back with significant results. Thus data dredging is also often a misused or misapplied form of data mining. The process of data dredging involves testing multiple hypotheses using a single data set by Brute-force search, exhaustively searching—perhaps for combinations of variables that might show a correlation, and perhaps for groups of cases or observations that show differences in their mean or in their breakdown by some other variable. Conventional tests of statistical significance are based on the probability that a particular result would arise if chance alone were at work, and necessarily accept some risk of Type I error, mistaken conclu ...
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Food And Drug Administration Amendments Act Of 2007
President of the United States George W. Bush signed the Food and Drug Administration Amendments Act of 2007 (FDAAA) on September 27, 2007. This law reviewed, expanded, and reaffirmed several existing pieces of legislation regulating the FDA. These changes allow the FDA to perform more comprehensive reviews of potential new drugs and devices. It was sponsored by Reps. Joe Barton and Frank Pallone and passed unanimously by the Senate. The FDAAA extended the authority to levy fees to companies applying for approval of drugs, expanded clinical trial guidelines for pediatric drugs, and created the priority review voucher program, amongst other items. Title I: Prescription Drug User Fee Amendments of 2007 Title I amends the Federal Food, Drug, and Cosmetic Act to include post-marketing safety activities in the review of drug application. This included developing and using improved adverse event data collection systems and improved analytical tools to assess potential safety prob ...
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Clinical Trial Registration
Preregistration is the practice of registering the hypotheses, methods, or analyses of a scientific study before it is conducted. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration has the goal to transparently evaluate the severity of hypothesis tests,, and can have a number of secondary goals (which can also be achieved without preregistering ), including (a) facilitating and documenting research plans, (b) identifying and reducing questionable research practices and researcher biases, (c) distinguishing between confirmatory and exploratory analyses, and, in the case of Registered Reports, (d) facilitating results-blind peer review, and (e) reducing publication bias. A number of research practices such as p-hacking, publication bias, data dredging, inappropriate forms of ...
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AllTrials
AllTrials (sometimes called All Trials or AllTrials.net) is a project advocating that clinical research adopt the principles of open research. The project summarizes itself as "All trials registered, all results reported": that is, all clinical trials should be listed in a clinical trials registry, and their results should always be shared as open data. At the center of the organisation is a petition signed by over 85,000 individuals and 599 organisations (as of August 2015): Ben Goldacre, author of '' Bad Science'' and '' Bad Pharma'', is a founder of the campaign and its most public spokesperson. In 2016, he participated in the launch of the OpenTrials database. AllTrials is an international initiative of Bad Science, '' BMJ'', Centre for Evidence-based Medicine, Cochrane Collaboration, James Lind Initiative, '' PLOS'' and Sense about Science and is being led in the US by Sense about Science USA, Dartmouth's Geisel School of Medicine and the Dartmouth Institute for He ...
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Researcher Degrees Of Freedom
Researcher degrees of freedom is a concept referring to the inherent flexibility involved in the process of designing and conducting a scientific experiment, and in analyzing its results. The term reflects the fact that researchers can choose between multiple ways of collecting and analyzing data, and these decisions can be made either arbitrarily or because they, unlike other possible choices, produce a positive and statistically significant result. The researcher degrees of freedom has positives such as affording the ability to look at nature from different angles, allowing new discoveries and hypotheses to be generated. However, researcher degrees of freedom can lead to data dredging and other questionable research practices where the different interpretations and analyses are taken for granted Their widespread use represents an inherent methodological limitation in scientific research, and contributes to an inflated rate of false-positive findings. They can also lead to ove ...
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Microeconomics
Microeconomics is a branch of economics that studies the behavior of individuals and firms in making decisions regarding the allocation of scarce resources and the interactions among these individuals and firms. Microeconomics focuses on the study of individual markets, sectors, or industries as opposed to the economy as a whole, which is studied in macroeconomics. One goal of microeconomics is to analyze the market mechanisms that establish relative prices among goods and services and allocate limited resources among alternative uses. Microeconomics shows conditions under which free markets lead to desirable allocations. It also analyzes market failure, where markets fail to produce efficient results. While microeconomics focuses on firms and individuals, macroeconomics focuses on the total of economic activity, dealing with the issues of growth, inflation, and unemployment—and with national policies relating to these issues. Microeconomics also deals with the effects of ...
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Center For Open Science
The Center for Open Science is a non-profit technology organization based in Charlottesville, Virginia with a mission to "increase the openness, integrity, and reproducibility of scientific research." Brian Nosek and Jeffrey Spies founded the organization in January 2013, funded mainly by the Laura and John Arnold Foundation and others. The organization began with work in reproducibility of psychology research, with the large-scale initiative Reproducibility Project: Psychology. A second reproducibility project for cancer biology research has also been started through a partnership with Science Exchange. In March 2017, the Center published a detailed strategic plan. Brian Nosek posted a letter outlining the history of the Center and future directions. In 2020, the Center received a grant from Fast Grants to promote the publication of COVID-19 research on the platform. In 2021, the Center for Open Science was honored with the in the institutional category for their contrib ...
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European Journal Of Personality
The ''European Journal of Personality'' (EJP) is the official bimonthly academic journal of the European Association of Personality Psychology covering research on personality, published by SAGE Publishing. According to citation reports based on impact factor, the journal ranked seventh of all the empirical journals in the social-personality field. EJP seeks to promote the development of empirical and theoretical work in personality psychology. It publishes papers relevant to advancing the field of personality in the broadest sense, and encompasses topics such as the nature of personality, expressions of personality in a social context, personality development, and the consequences of personality. EJP also publishes work on methodological advances in research on personality. It is abstracted inservices including PsycINFO and Social Sciences Citation Index The Social Sciences Citation Index (SSCI) is a commercial citation index product of Clarivate Analytics. It was originally de ...
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Nature Human Behaviour
''Nature Human Behaviour'' is a monthly multidisciplinary online-only peer-reviewed scientific journal covering all aspects of human behaviour. It was established in January 2017 and is published by Nature Portfolio. The editor-in-chief is Stavroula Kousta. According to the ''Journal Citation Reports'', the journal has a 2022 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 29.9. Potential Harms Policy In August 2022, the journal published an editorial article called "''Science must respect the dignity and rights of all humans''", to counter structural inequalities and discrimination in society in science. It stated that editors have the right to amend, refuse, or retract content which can be "disparag ng, "exclusionary" or content that "undermines the dignit ...
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Editor-in-chief
An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The editor-in-chief heads all departments of the organization and is held accountable for delegating tasks to staff members and managing them. The term is often used at newspapers, magazines, yearbooks, and television news programs. The editor-in-chief is commonly the link between the publisher or proprietor and the editorial staff. Responsibilities Typical responsibilities of editors-in-chief include: * Ensuring that content is journalistically objective * Fact-checking, spelling, grammar, writing style, page design and photos * Rejecting writing that appears to be plagiarized, ghostwritten, published elsewhere, or of little interest to readers * Evaluating and editing content * Contributing editorial pieces * Motivating and developing editorial staff * Ensuring the final draft is complete * Handling reader compl ...
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Psychological Science (journal)
''Psychological Science'', the flagship journal of the Association for Psychological Science, is a monthly, peer-reviewed scientific journal published by SAGE Publications. The journal publishes research articles, short reports, and research reports covering all aspects of psychology. Its editor-in-chief is Simine Vazire (University of Melbourne). Past editors The following persons have been editors-in-chief: *Patricia Bauer (Emory University) (2020–2023) * Stephen Lindsay, University of Victoria (2015–2019) *Eric Eich, University of British Columbia (2012–2015) *Robert V. Kail, Purdue University (2007–2012) * James E. Cutting, Cornell University (2003–2007) * Sam Glucksberg, Princeton University (1999–2003) * John F. Kihlstrom, University of California, Berkeley * William Kaye Estes, Indiana University Indiana University (IU) is a state university system, system of Public university, public universities in the U.S. state of Indiana. The system has two core camp ...
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Animal Study Registry
Animal Study Registry is an online registry for the preregistration of research studies involving animals. Animal Study Registry was launched in January 2019 and can be used by scientists worldwide. History The reproducibility of animal test results in biomedical research has been questioned repeatedly in the past. Discussions about this replication crisis have already reached the public. In clinical research, the call for transparency led to the introduction of clinical trial registries that disclose the experimental design of clinical trials before the study is conducted. In order to increase the transparency and the quality in the field of preclinical and basic research, the establishment of so-called centralized animal study registries was suggested. The German Federal Institute for Risk Assessment (BfR), as a scientifically independent research institution, has decided to provide an international freely accessible platform for the pre-registration of studies involving anim ...
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