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Randomized Assignment
Random assignment or random placement is an experimental technique for assigning human subject research, human participants or animal testing, animal subjects to different groups in an experiment (e.g., treatment and control groups, a treatment group versus a control group) using wikt:randomization#Noun, randomization, such as by a chance procedure (e.g., coin flipping, flipping a coin) or a random number generation, random number generator. This ensures that each participant or subject has an equal chance of being placed in any group. Random assignment of participants helps to ensure that any differences between and within the groups are not systematic error, systematic at the outset of the experiment. Thus, any differences between groups recorded at the end of the experiment can be more confidently attributed to the experimental procedures or treatment. Random assignment, blind experiment, blinding, and scientific control, controlling are key aspects of the design of experiments ...
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Experiment
An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into cause-and-effect by demonstrating what outcome occurs when a particular factor is manipulated. Experiments vary greatly in goal and scale but always rely on repeatable procedure and logical analysis of the results. There also exist natural experimental studies. A child may carry out basic experiments to understand how things fall to the ground, while teams of scientists may take years of systematic investigation to advance their understanding of a phenomenon. Experiments and other types of hands-on activities are very important to student learning in the science classroom. Experiments can raise test scores and help a student become more engaged and interested in the material they are learning, especially when used over time. Experiments can vary from personal and informal natural comparisons ...
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Low-discrepancy Sequence
In mathematics, a low-discrepancy sequence is a sequence with the property that for all values of N, its subsequence x_1, \ldots, x_N has a low discrepancy of a sequence, discrepancy. Roughly speaking, the discrepancy of a sequence is low if the proportion of points in the sequence falling into an arbitrary set ''B'' is close to proportional to the Measure (mathematics), measure of ''B'', as would happen on average (but not for particular samples) in the case of an equidistributed sequence. Specific definitions of discrepancy differ regarding the choice of ''B'' (hyperspheres, Hypercube, hypercubes, etc.) and how the discrepancy for every B is computed (usually normalized) and combined (usually by taking the worst value). Low-discrepancy sequences are also called quasirandom sequences, due to their common use as a replacement of uniformly distributed random sequence, random numbers. The "quasi" modifier is used to denote more clearly that the values of a low-discrepancy sequence ar ...
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Randomized Experiment
In scientific method, science, randomized experiments are the experiments that allow the greatest reliability and validity of statistical estimates of treatment effects. Randomization-based inference is especially important in experimental design and in survey sampling. Overview In the statistical theory of design of experiments, randomization involves randomly allocating the experimental units across the treatment groups. For example, if an experiment compares a new drug against a standard drug, then the patients should be allocated to either the new drug or to the standard drug control using randomization. Randomized experimentation is ''not'' haphazard. Randomization reduces bias by equalising other factors that have not been explicitly accounted for in the experimental design (according to the law of large numbers). Randomization also produces ignorability, ignorable designs, which are valuable in statistical model, model-based statistical inference, especially Bayesian infe ...
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Isis (journal)
''Isis'' is a quarterly peer-reviewed academic journal published by the University of Chicago Press for the History of Science Society. It covers the history of science, history of medicine, and the history of technology, as well as their cultural influences. It contains original research articles and extensive book reviews and review essays. Furthermore, sections devoted to one particular topic are published in each issue in open access. These sections consist of the Focus section, the Viewpoint section and the Second Look section. History The journal was established by George Sarton and the first issue appeared in March 1913. Contributions were originally in any of four European languages (English, French, German, and Italian), but since the 1920s, only English has been used. Publication is partly supported by an endowment from the Dibner Fund. Two associated publications are ''Osiris'' (established 1936 by Sarton) and the ''Isis Current Bibliography''. The publication o ...
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Repeated Measures Design
Repeated measures design is a research design that involves multiple measures of the same variable taken on the same or matched subjects either under different conditions or over two or more time periods. For instance, repeated measurements are collected in a longitudinal study in which change over time is assessed. Crossover studies A popular repeated-measures design is the crossover study. A crossover study is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies, many important crossover studies are controlled experiments. Crossover designs are common for experiments in many scientific disciplines, for example psychology, education, pharmaceutical science, and health care, especially medicine. Randomized, controlled, crossover experiments are especially important in health care. In a randomized clinical trial, the subjects are randomly assigned treatments. When such a trial ...
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Joseph Jastrow
Joseph Jastrow (January 30, 1863 – January 8, 1944) was a Polish-born American psychologist renowned for his contributions to experimental psychology, design of experiments, and psychophysics. He also worked on the phenomena of optical illusions, and a number of well-known optical illusions (notably the Jastrow illusion) that were either first reported in or popularized by his work. Jastrow believed that everyone had their own, often incorrect, preconceptions about psychology. One of his ultimate goals was to use the scientific method to identify truth from error, and educate the general public, which Jastrow accomplished through speaking tours, popular print media, and the radio. Biography Jastrow was born in Warsaw, Congress Poland, Poland. A son of Talmud scholar Marcus Jastrow, Joseph Jastrow was the younger brother of the Oriental studies, orientalist, Morris Jastrow, Jr. Joseph Jastrow came to Philadelphia, Pennsylvania, Philadelphia in 1866 and received his bachelor ...
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Charles Sanders Peirce Bibliography
This Charles Sanders Peirce bibliography consolidates numerous references to the writings of Charles Sanders Peirce, including letters, manuscripts, publications, and . For an extensive chronological list of Peirce's works (titled in English), see the (Chronological Overview) on the (Writings) page for Charles Sanders Peirce. Abbreviations Click on abbreviation in order to jump down this page to the relevant edition information. Click on the abbreviation appearing with that edition information in order to return here. Main editions (posthumous) Other Primary literature Bibliographies and microfilms Other bibliographies of primary literature * Burks, Arthur W. (1958). "Bibliography of the Works of Charles Sanders Peirce." CP 8:260–321. * Cohen, Morris R. (1916). "Charles S. Peirce and a Tentative Bibliography of His Published Writings." '' The Journal of Philosophy, Psychology, and Scientific Methods'' 13(26):726–37. *Fisch, Max H. (1964). "A First Supplement ...
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Charles Sanders Peirce
Charles Sanders Peirce ( ; September 10, 1839 – April 19, 1914) was an American scientist, mathematician, logician, and philosopher who is sometimes known as "the father of pragmatism". According to philosopher Paul Weiss (philosopher), Paul Weiss, Peirce was "the most original and versatile of America's philosophers and America's greatest logician". Bertrand Russell wrote "he was one of the most original minds of the later nineteenth century and certainly the greatest American thinker ever". Educated as a chemist and employed as a scientist for thirty years, Peirce meanwhile made major contributions to logic, such as theories of Algebraic logic, relations and Quantifier (logic), quantification. Clarence Irving Lewis, C. I. Lewis wrote, "The contributions of C. S. Peirce to symbolic logic are more numerous and varied than those of any other writer—at least in the nineteenth century." For Peirce, logic also encompassed much of what is now called epistemology and the philoso ...
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Null Hypothesis
The null hypothesis (often denoted ''H''0) is the claim in scientific research that the effect being studied does not exist. The null hypothesis can also be described as the hypothesis in which no relationship exists between two sets of data or variables being analyzed. If the null hypothesis is true, any experimentally observed effect is due to chance alone, hence the term "null". In contrast with the null hypothesis, an alternative hypothesis (often denoted ''H''A or ''H''1) is developed, which claims that a relationship does exist between two variables. Basic definitions The null hypothesis and the ''alternative hypothesis'' are types of conjectures used in statistical tests to make statistical inferences, which are formal methods of reaching conclusions and separating scientific claims from statistical noise. The statement being tested in a test of statistical significance is called the null hypothesis. The test of significance is designed to assess the strength of the e ...
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Statistical Significance
In statistical hypothesis testing, a result has statistical significance when a result at least as "extreme" would be very infrequent if the null hypothesis were true. More precisely, a study's defined significance level, denoted by \alpha, is the probability of the study rejecting the null hypothesis, given that the null hypothesis is true; and the p-value, ''p''-value of a result, ''p'', is the probability of obtaining a result at least as extreme, given that the null hypothesis is true. The result is said to be ''statistically significant'', by the standards of the study, when p \le \alpha. The significance level for a study is chosen before data collection, and is typically set to 5% or much lower—depending on the field of study. In any experiment or Observational study, observation that involves drawing a Sampling (statistics), sample from a Statistical population, population, there is always the possibility that an observed effect would have occurred due to sampling error al ...
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Average
In colloquial, ordinary language, an average is a single number or value that best represents a set of data. The type of average taken as most typically representative of a list of numbers is the arithmetic mean the sum of the numbers divided by how many numbers are in the list. For example, the mean or average of the numbers 2, 3, 4, 7, and 9 (summing to 25) is 5. Depending on the context, the most representative statistics, statistic to be taken as the average might be another measure of central tendency, such as the mid-range, median, Mode (statistics), mode or geometric mean. For example, the average income, personal income is often given as the median the number below which are 50% of personal incomes and above which are 50% of personal incomes because the mean would be higher by including personal incomes from a few billionaires. General properties If all numbers in a list are the same number, then their average is also equal to this number. This property is shared by each o ...
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Levels Of Evidence
A hierarchy of evidence, comprising levels of evidence (LOEs), that is, evidence levels (ELs), is a heuristic used to rank the relative strength of results obtained from experimental research, especially medical research. There is broad agreement on the relative strength of large-scale, epidemiological studies. More than 80 different hierarchies have been proposed for assessing medical evidence. The design of the study (such as a case report In medicine, a case report is a detailed report of the symptoms, signs, diagnosis, treatment, and follow-up of an individual patient. Case reports may contain a demographic profile of the patient, but usually describe an unusual or novel occurrenc ... for an individual patient or a blinded experiment, blinded randomized controlled trial) and the endpoints measured (such as survival or quality of life) affect the strength of the evidence. In clinical research, the best evidence for treatment efficacy is mainly from meta-analysis, meta-analyse ...
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