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Phthisiatrist
The history of tuberculosis encompasses the origins, evolution, and spread of tuberculosis (TB) throughout human history, as well as the development of medical understanding, treatments, and control methods for this ancient disease. Tuberculosis is an infectious disease caused by bacteria of the ''Mycobacterium tuberculosis'' complex (MTBC). Throughout history, tuberculosis has been known by differing names, including consumption, phthisis, and the White Plague. Paleopathological evidence finds tuberculosis in humans since at least the Neolithic (approximately 10,000-11,000 years ago), with molecular studies suggesting a much earlier emergence and co-evolution with humans. Phylogenetic analyses indicate that the TB originated in Africa and evolved alongside human populations for tens of thousands of years. The disease spread globally through human migrations, adapting to different human populations and eventually developing into several distinct lineages with varying geograph ...
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Atlit Yam
Atlit Yam (Hebrew language, Hebrew: עתלית ים) is a submerged Pre-Pottery Neolithic, Pre Pottery Neolithic C (PPNC) archaeological site located 300–400 meters off the coast of Atlit (modern town), Atlit, Israel. Dating from the late 7th to the early 6th millennia BCE, Atlit Yam provides the earliest known evidence for a community relying on pastoralism, agriculture, and fishing as Subsistence agriculture, subsistence systems on the Levantine coast. As of 2004, it is the only marine archaeological site in the Mediterranean to contain ''in situ'' human burials. Location Atlit Yam once sat on a coastal peninsula in close vicinity to the Oren River as well as several fresh water springs. The beginning of the Holocene saw a Sea level rise, rise in sea levels which left the site completely submerged by approximately 7000 BP. The contemporary coastline is assumed to have been about 1km west of the present coast. It is currently 8–12 m (25–40ft) beneath sea level in the Medite ...
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Psoas Major Muscle
The psoas major ( or ; from ) is a long fusiform muscle located in the lateral lumbar region between the vertebral column and the brim of the lesser pelvis. It joins the iliacus muscle to form the iliopsoas. In other animals, this muscle is equivalent to the tenderloin. Structure The psoas major is divided into a superficial and a deep part. The deep part originates from the transverse processes of lumbar vertebrae L1–L5. The superficial part originates from the lateral surfaces of the last thoracic vertebra, lumbar vertebrae L1–L4, and the neighboring intervertebral discs. The lumbar plexus lies between the two layers. Together, the iliacus muscle and the psoas major form the iliopsoas, which is surrounded by the iliac fascia. The iliopsoas runs across the iliopubic eminence through the muscular lacuna to its insertion on the lesser trochanter of the femur. The iliopectineal bursa separates the tendon of the iliopsoas muscle from the external surface of the hip-joi ...
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University Of California, Irvine
The University of California, Irvine (UCI or UC Irvine) is a Public university, public Land-grant university, land-grant research university in Irvine, California, United States. One of the ten campuses of the University of California system, UCI offers 87 undergraduate degrees and 129 graduate and professional degrees, and roughly 30,000 undergraduates and 7,000 graduate students were enrolled at UCI as of Fall 2024. The university is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity" and had $609.6 million in research and development expenditures in 2023, ranking it 56th nationally. UCI became a member of the Association of American Universities in 1996. The university administers the UC Irvine Medical Center, a large teaching hospital in Orange, California, Orange, and UC Irvine Health Sciences, its affiliated health sciences system; the University of California, Irvine, Arboretum; and a po ...
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Nofretete Neues Museum
Nefertiti () () was a queen of the Eighteenth Dynasty of Egypt, 18th Dynasty of Ancient Egypt, the Great Royal Wife, great royal wife of Pharaoh Akhenaten. Nefertiti and her husband were known for their radical overhaul of state religious policy, in which they promoted the earliest known form of monotheism, Atenism, centered on Aten, the sun disc and its direct connection to the royal household. With her husband, she reigned at what was arguably the wealthiest period of ancient Egyptian history. After her husband's death, some scholars believe that Nefertiti ruled briefly as the female pharaoh known by the throne name, Neferneferuaten and before the ascension of Tutankhamun, although this identification is Neferneferuaten#Nefertiti, a matter of ongoing debate. If Nefertiti did rule as pharaoh, her reign was marked by the fall of Amarna and relocation of the capital back to the traditional city of Thebes, Egypt, Thebes. In the 20th century, Nefertiti was made famous by the disco ...
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Romanticism
Romanticism (also known as the Romantic movement or Romantic era) was an artistic and intellectual movement that originated in Europe towards the end of the 18th century. The purpose of the movement was to advocate for the importance of subjectivity and objectivity (philosophy), subjectivity, imagination, and appreciation of nature in society and culture in response to the Age of Enlightenment and the Industrial Revolution. Romanticists rejected the social conventions of the time in favour of a moral outlook known as individualism. They argued that passion (emotion), passion and intuition were crucial to understanding the world, and that beauty is more than merely an classicism, affair of form, but rather something that evokes a strong emotional response. With this philosophical foundation, the Romanticists elevated several key themes to which they were deeply committed: a Reverence (emotion), reverence for nature and the supernatural, nostalgia, an idealization of the past as ...
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Cachexia
Cachexia () is a syndrome that happens when people have certain illnesses, causing muscle loss that cannot be fully reversed with improved nutrition. It is most common in diseases like cancer, Heart failure, congestive heart failure, chronic obstructive pulmonary disease, chronic kidney disease, and AIDS. These conditions change how the body handles inflammation, metabolism, and brain signaling, leading to muscle loss and other harmful changes to body composition over time. Unlike weight loss from not eating enough, cachexia mainly affects muscle and can happen with or without fat loss. Diagnosis of cachexia is difficult because there are no clear guidelines, and its occurrence varies from one affected person to the next. Like malnutrition, cachexia can lead to worse health outcomes and lower quality of life. Definition Cachexia is hard to define because it often happens alongside malnutrition and sarcopenia. Since there are no clear rules separating these conditions, experts ...
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Coevolution
In biology, coevolution occurs when two or more species reciprocally affect each other's evolution through the process of natural selection. The term sometimes is used for two traits in the same species affecting each other's evolution, as well as gene-culture coevolution. Charles Darwin mentioned evolutionary interactions between flowering plants and insects in ''On the Origin of Species'' (1859). Although he did not use the word coevolution, he suggested how plants and insects could evolve through reciprocal evolutionary changes. Naturalists in the late 1800s studied other examples of how interactions among species could result in reciprocal evolutionary change. Beginning in the 1940s, plant pathologists developed breeding programs that were examples of human-induced coevolution. Development of new crop plant varieties that were resistant to some diseases favored rapid evolution in pathogen populations to overcome those plant defenses. That, in turn, required the development of ...
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Neolithic Demographic Transition
The Neolithic demographic transition was a period of rapid population growth following the adoption of agriculture by prehistoric societies (the Neolithic Revolution). It was a demographic transition caused by an abrupt increase in birth rates due to the increased food supply and decreased mobility of farmers compared to foragers. Eventually the mortality rate in farming societies also increased to the point where the population stabilised again, possibly because settling down in one place, in close proximity to animals, encouraged the spread of zoonotic and waterborne diseases. The transition is estimated to have taken about a thousand years on average, although the onset and duration of the transition varied widely in the different parts of the world. Evidence for the Neolithic demographic transition include an increase in juvenile skeletons in prehistoric cemeteries and a general increase in the density of archaeological remains following the start of the Neolithic. It is known ...
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Domestication Of Vertebrates
The domestication of vertebrates is the mutual relationship between vertebrate animals, including birds and mammals, and the humans who influence their care and reproduction. Charles Darwin recognized a small number of traits that made domesticated species different from their wild ancestors. He was also the first to recognize the difference between conscious selective breeding (i.e. artificial selection) in which humans directly select for desirable traits, and unconscious selection where traits evolve as a by-product of natural selection or from selection of other traits. There is a genetic difference between domestic and wild populations. There is also a genetic difference between the domestication traits that researchers believe to have been essential at the early stages of domestication, and the improvement traits that have appeared since the split between wild and domestic populations. Domestication traits are generally fixed within all domesticates, and were selected during ...
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Hunter-gatherer
A hunter-gatherer or forager is a human living in a community, or according to an ancestrally derived Lifestyle, lifestyle, in which most or all food is obtained by foraging, that is, by gathering food from local naturally occurring sources, especially wild edible plants but also insects, Fungus, fungi, Honey hunting, honey, Eggs as food, bird eggs, or anything safe to eat, or by hunting game (pursuing or trapping and killing Wildlife, wild animals, including Fishing, catching fish). This is a common practice among most vertebrates that are omnivores. Hunter-gatherer Society, societies stand in contrast to the more Sedentism, sedentary Agrarian society, agricultural societies, which rely mainly on cultivating crops and raising domesticated animals for food production, although the boundaries between the two ways of living are not completely distinct. Hunting and gathering was humanity's original and most enduring successful Competition (biology), competitive adaptation in the nat ...
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Upper Paleolithic
The Upper Paleolithic (or Upper Palaeolithic) is the third and last subdivision of the Paleolithic or Old Stone Age. Very broadly, it dates to between 50,000 and 12,000 years ago (the beginning of the Holocene), according to some theories coinciding with the appearance of behavioral modernity in early modern humans. It is followed by the Mesolithic. Anatomically modern humans (i.e. ''Homo sapiens'') are believed to have emerged in Africa around 300,000 years ago. It has been argued by some that their ways of life changed relatively little from that of archaic humans of the Middle Paleolithic, until about 50,000 years ago, when there was a marked increase in the diversity of Artefact (archaeology), artefacts found associated with modern human remains. This period coincides with the most common date assigned to early human migrations, expansion of modern humans from Africa throughout Asia and Eurasia, which may have contributed to the Neanderthal extinction, extinction of th ...
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