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Hemostatic Agent
An antihemorrhagic () agent is a substance that promotes hemostasis (a process which stops bleeding). It may also be known as a hemostatic (also spelled haemostatic) agent. Antihemorrhagic agents used in medicine have various mechanisms of action: * Systemic drugs work by inhibiting fibrinolysis or promoting coagulation. * Locally acting hemostatic agents work by causing vasoconstriction or promoting platelet aggregation. Medical uses Hemostatic agents are used during surgical procedures to achieve hemostasis and are categorized as hemostats, sealants and adhesives. They vary based on their mechanism of action, composition, ease of application, adherence to tissue, immunogenicity and cost. These agents permit rapid hemostasis, better visualization of the surgical area, shorter operative times, decreased requirement for transfusions, decreased wound healing time and overall improvement in patient recovery time. Types Systemic There are several classes of antihemorrhagic drug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemostasis
In biology, hemostasis or haemostasis is a process to prevent and stop bleeding, meaning to keep blood within a damaged blood vessel (the opposite of hemostasis is hemorrhage). It is the first stage of wound healing. Hemostasis involves three major steps: * vasoconstriction * temporary blockage of a hole in a damaged blood vessel by a platelet plug * blood coagulation (formation of fibrin clots) Coagulation, the changing of blood from a liquid to a gel which forms the fibrin clots, is essential to hemostasis. Intact blood vessels moderate blood's tendency to form clots. The endothelial cells of intact vessels prevent blood clotting with a heparin-like molecule and thrombomodulin, and prevent platelet aggregation with nitric oxide and prostacyclin. When endothelium of a blood vessel is damaged, the endothelial cells stop secretion of coagulation and aggregation inhibitors and instead secrete von Willebrand factor, which initiates the maintenance of hemostasis after in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypothermia
Hypothermia is defined as a body core temperature below in humans. Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion. In moderate hypothermia, shivering stops and confusion increases. In severe hypothermia, there may be hallucinations and paradoxical undressing, in which a person removes their clothing, as well as an increased risk of the heart stopping. Hypothermia has two main types of causes. It classically occurs from exposure to cold weather and cold water immersion. It may also occur from any condition that decreases heat production or increases heat loss. Commonly, this includes alcohol intoxication but may also include low blood sugar, anorexia and advanced age. Body temperature is usually maintained near a constant level of through thermoregulation. Efforts to increase body temperature involve shivering, increased voluntary activity, and putting on warmer clothing. Hypothermia may be diagnosed based on either a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aluminium Sulfate
Aluminium sulfate is a salt with the chemical formula, formula . It is soluble in water and is mainly used as a Coagulation (water treatment), coagulating agent (promoting particle collision by neutralizing charge) in the purification of drinking water and wastewater treatment plants, and also in paper manufacturing. The anhydrous form occurs naturally as a rare mineral millosevichite, found for example in volcanic environments and on burning coal-mining waste dumps. Aluminium sulfate is rarely, if ever, encountered as the anhydrous salt. It forms a number of different hydrates, of which the hexadecahydrate and octadecahydrate are the most common. The heptadecahydrate, whose formula can be written as , occurs naturally as the mineral alunogen. Aluminium sulfate is sometimes called alum or papermaker's alum in certain industries. However, the name "alum" is more commonly and properly used for any double sulfate salt with the generic formula , where ''X'' is a valence (chemistry) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anhydrous
A substance is anhydrous if it contains no water. Many processes in chemistry can be impeded by the presence of water; therefore, it is important that water-free reagents and techniques are used. In practice, however, it is very difficult to achieve perfect dryness; anhydrous compounds gradually absorb water from the atmosphere so they must be stored carefully. Solids Many salts and solids can be dried using heat, or under vacuum. Desiccators can also be used to store reagents in dry conditions. Common desiccants include phosphorus pentoxide and silica gel. Chemists may also require dry glassware for sensitive reactions. This can be achieved by drying glassware in an oven, by flame, or under vacuum. Dry solids can be produced by freeze-drying, which is also known as lyophilization. Liquids or solvents In many cases, the presence of water can prevent a reaction from happening, or cause undesirable products to form. To prevent this, anhydrous solvents must be used when perform ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medication
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmacotherapy) is an important part of the medicine, medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are Drug class, classified in many ways. One of the key divisions is by level of controlled substance, control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the medical prescription) from over-the-counter drugs (those that consumers can order for themselves). Medicines may be classified by mode of action, route of administration, biological system affected, or therapeutic effects. The World Health Organization keeps a list of essential medicines. Drug discovery and drug development are complex and expensive endeavors undertake ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caustic Pencil
A caustic pencil (or silver nitrate stick) is a device for applying topical medication containing silver nitrate and potassium nitrate, used to chemically cauterize skin, providing hemostasis or permanently destroying unwanted tissue such as a wart, skin tag, aphthous ulcers, or over-production of granulation tissue. They are not used as a treatment for minor skin cuts, and are not to be confused with a styptic pencil. The silver and potassium nitrates in caustic pencils is in a dried, solid form at the tip of a wooden or plastic stick. When the material is applied to a wound or lesion, the tissue moisture or blood dissolves the dried nitrate salts, which then chemically burn the tissue. It requires moisture for activation. Silver nitrate sticks are often used for minor hemostasis where patients are not under general anesthesia, and where electrocautery would be painful and inconvenient. One common use of silver nitrate sticks is in emergency medicine, to control epistaxis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Astringent
An astringent (sometimes called adstringent) is a chemical that shrinks or constricts body tissues. The word derives from the Latin '' adstringere'', which means "to bind fast". Astringency, the dry, puckering or numbing mouthfeel caused by the tannins in unripe fruits, lets the fruit mature by deterring eating. Tannins, being a kind of polyphenol, bind salivary proteins and make them precipitate and aggregate, producing a rough, "sandpapery", or dry sensation in the mouth. Smoking tobacco is also reported to have an astringent effect. In a scientific study, astringency was still detectable by subjects who had local anesthesia applied to their taste nerves, but not when both these and the trigeminal nerves were disabled. Uses In medicine, astringents cause constriction or contraction of mucous membranes and exposed tissues and are often used internally to reduce discharge of blood serum and mucous secretions. This can happen with a sore throat, hemorrhages, diarrhe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Vessel
Blood vessels are the tubular structures of a circulatory system that transport blood throughout many Animal, animals’ bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the Tissue (biology), tissues of a Body (biology), body. They also take waste and carbon dioxide away from the tissues. Some tissues such as cartilage, epithelium, and the lens (anatomy), lens and cornea of the eye are not supplied with blood vessels and are termed ''avascular''. There are five types of blood vessels: the arteries, which carry the blood away from the heart; the arterioles; the capillaries, where the exchange of water and chemicals between the blood and the tissues occurs; the venules; and the veins, which carry blood from the capillaries back towards the heart. The word ''vascular'', is derived from the Latin ''vas'', meaning ''vessel'', and is mostly used in relation to blood vessels. Etymology * artery – late Middle English; from Latin ''arteria'', from Gree ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tissue (biology)
In biology, tissue is an assembly of similar cells and their extracellular matrix from the same embryonic origin that together carry out a specific function. Tissues occupy a biological organizational level between cells and a complete organ. Accordingly, organs are formed by the functional grouping together of multiple tissues. The English word "tissue" derives from the French word "", the past participle of the verb tisser, "to weave". The study of tissues is known as histology or, in connection with disease, as histopathology. Xavier Bichat is considered as the "Father of Histology". Plant histology is studied in both plant anatomy and physiology. The classical tools for studying tissues are the paraffin block in which tissue is embedded and then sectioned, the histological stain, and the optical microscope. Developments in electron microscopy, immunofluorescence, and the use of frozen tissue-sections have enhanced the detail that can be observed in tissues. With t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
QuikClot
QuikClot is a brand of wound dressings that contain kaolinite, kaolin, a antihemorrhagic, hemostatic agent. The brand is owned by Teleflex. It is primarily used by Tactical emergency medical services, militaries, surgeon, surgeons, Emergency Medical Services, EMS, and first responding civilians to stop Bleeding, traumatic hemorrhage. History The use of a sterilized molecular sieve material, such as zeolite, in a binding material to treat wounds was patented by Frank Hursey in 1989. Following the September 11 attacks, the US armed forces conducted a study comparing different antihemorrhagic technologies, in which QuikClot received the best score. Another study found that when used to treat lethal groin injuries in swine, the treated animals had a 100% survival rate. Following these tests, the US armed forces approved its use in Afghanistan and Iraq. Zeolite The original formulation of the product contained the active ingredient zeolite, which promoted blood clotting. The zeolit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
